spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zacharias, D.
Right arrow Articles by Reichert, H.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Zacharias, D.
Right arrow Articles by Reichert, H.

Development, Vol 118, Issue 3 941-955, Copyright © 1993 by Company of Biologists

JOURNAL ARTICLES

Neurogenesis in the insect brain: cellular identification and molecular characterization of brain neuroblasts in the grasshopper embryo

D. Zacharias, J. Leslie, D. Williams, T. Meier and H. Reichert

Brain neuroblasts in the embryonic grasshopper were studied by toluidine blue staining, BrdU incorporation, and immunocytochemistry in whole-mounts as well as by reconstruction of stained serial sections. Large dividing neuroblasts are observed by the 25% stage. During early neurogenesis these neuroblasts generate their progeny through mechanisms similar to those that occur in the segmental ganglia; each neuroblast divides asymmetrically to produce a chain of ganglion mother cells, and each ganglion mother cell divides symmetrically to produce a pair of neurons. Approximately 130 mitotically active, large neuroblasts are found in each brain hemisphere at the 30- 45% stages. Through morphogenetic movements that occur between the 30-35% stages these neuroblasts become located in positions which are predictive of the major brain regions that they give rise to. Many of the brain neuroblasts can be identified as individuals based on their stereotyped position in the neurogenic array. Immunocytochemical experiments with antibodies against, engrailed, fasciclin I and TERM-1 show that brain neuroblasts can also be characterized by their expression of cell-specific molecular labels. These studies indicate that many features of the complex mature insect brain derive from a surprisingly simple and stereotyped set of neuronal precursor cells. Thus, many of the concepts and methods that have been used to study neurogenesis in the simpler segmental ganglia may also be applicable to the insect brai


This article has been cited by other articles:


Home page
 Chem SensesHome page
M. Schmidt
The Olfactory Pathway of Decapod Crustaceans--An Invertebrate Model for Life-Long Neurogenesis
Chem Senses, May 1, 2007; 32(4): 365 - 384.
[Abstract] [Full Text] [PDF]

Home page
 Learn. Mem.Home page
D. Malun
Early Development of Mushroom Bodies in the Brain of the Honeybee Apis mellifera as Revealed by BrdU Incorporation and Ablation Experiments
Learn. Mem., May 1, 1998; 5(1): 90 - 101.
[Abstract] [Full Text]

Home page
 DevelopmentHome page
S Therianos, S Leuzinger, F Hirth, C. Goodman, and H Reichert
Embryonic development of the Drosophila brain: formation of commissural and descending pathways
Development, January 11, 1995; 121(11): 3849 - 3860.
[Abstract] [PDF]

Home page
 DevelopmentHome page
G Boyan, S Therianos, J. Williams, and H Reichert
Axogenesis in the embryonic brain of the grasshopper Schistocerca gregaria: an identified cell analysis of early brain development
Development, January 1, 1995; 121(1): 75 - 86.
[Abstract] [PDF]


© The Company of Biologists Ltd 1993