|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 120, Issue 8 2317-2328, Copyright © 1994 by Company of Biologists
JOURNAL ARTICLES |
JA Waddle, JA Cooper and RH Waterston
Department of Genetics, Washington University School of Medicine, St Louis, MO 63110.
During Caenorhabditis elegans embryogenesis, specific cells in the P1 lineage rotate their duplicated centrosome pair onto the anterior-posterior axis; this rotation is correlated with and necessary for a differential inheritance of cytoplasmic determinants in the daughter cells. Centrosome pair rotation is sensitive to inhibitors of actin and microtubule polymerization and may require microtubule attachment to a specific cortical site. We show that actin and the barbed-end binding protein, capping protein, transiently accumulate at this cortical site, possibly by assembly onto persistent remnants of previous cell divisions. Based on these observations, we propose a model for the molecular basis of centrosome rotation that is consistent with the dependence of rotation on actin filaments and microtubules.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  S. Crittenden and J. Kimble Preparation and Immunolabeling of Caenorhabditis elegans CSH Protocols, May 1, 2009; 2009(5): pdb.prot5216 - pdb.prot5216. [Abstract] [Full Text]
|
|
|
|
 |
|
 H. Zhang, A. R. Skop, and J. G. White Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos J. Cell Sci., January 15, 2008; 121(2): 155 - 161. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Leslie Centrosome choreography J. Cell Biol., January 30, 2006; 172(3): 328 - 328. [Full Text] [PDF]
|
|
|
|
 |
|
 D. R. Kovar, J.-Q. Wu, and T. D. Pollard Profilin-mediated Competition between Capping Protein and Formin Cdc12p during Cytokinesis in Fission Yeast Mol. Biol. Cell, May 1, 2005; 16(5): 2313 - 2324. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Cassata, G. Shemer, P. Morandi, R. Donhauser, B. Podbilewicz, and R. Baumeister ceh-16/engrailed patterns the embryonic epidermis of Caenorhabditis elegans Development, February 15, 2005; 132(4): 739 - 749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Ono, M. Parast, C. Alberico, G. M. Benian, and S. Ono Specific requirement for two ADF/cofilin isoforms in distinct actin-dependent processes in Caenorhabditis elegans J. Cell Sci., May 15, 2003; 116(10): 2073 - 2085. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-F. B. Tsou, W. Ku, A. Hayashi, and L. S. Rose PAR-dependent and geometry-dependent mechanisms of spindle positioning J. Cell Biol., March 17, 2003; 160(6): 845 - 855. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.-Y. Ji, M. Haghnia, C. Trusty, L. S. B. Goldstein, and G. Schubiger A Genetic Screen for Suppressors and Enhancers of the Drosophila Cdk1-Cyclin B Identifies Maternal Factors That Regulate Microtubule and Microfilament Stability Genetics, November 1, 2002; 162(3): 1179 - 1195. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Nagasato and T. Motomura Influence of the centrosome in cytokinesis of brown algae: polyspermic zygotes of Scytosiphon lomentaria (Scytosiphonales, Phaeophyceae) J. Cell Sci., June 15, 2002; 115(12): 2541 - 2548. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-F. B. Tsou, A. Hayashi, L. R. DeBella, G. McGrath, and L. S. Rose LET-99 determines spindle position and is asymmetrically enriched in response to PAR polarity cues in C. elegans embryos Development, January 10, 2002; 129(19): 4469 - 4481. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Kaltschmidt and A. H. Brand Asymmetric cell division: microtubule dynamics and spindle asymmetry J. Cell Sci., January 6, 2002; 115(11): 2257 - 2264. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Piekny and P. E. Mains Rho-binding kinase (LET-502) and myosin phosphatase (MEL-11) regulate cytokinesis in the early Caenorhabditis elegans embryo J. Cell Sci., January 6, 2002; 115(11): 2271 - 2282. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-E. Gomes, S. E. Encalada, K. A. Swan, C. A. Shelton, J. C. Carter, and B. Bowerman The maternal gene spn-4 encodes a predicted RRM protein required for mitotic spindle orientation and cell fate patterning in early C. elegans embryos Development, November 1, 2001; 128(21): 4301 - 4314. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Jantsch-Plunger, P. Gonczy, A. Romano, H. Schnabel, D. Hamill, R. Schnabel, A. A. Hyman, and M. Glotzer Cyk-4: A Rho Family Gtpase Activating Protein (Gap) Required for Central Spindle Formation and Cytokinesis J. Cell Biol., June 26, 2000; 149(7): 1391 - 1404. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Pichler, P. Gonczy, H. Schnabel, A. Pozniakowski, A. Ashford, R. Schnabel, and A. A. Hyman OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos Development, May 15, 2000; 127(10): 2063 - 2073. [Abstract] [PDF]
|
|
|
|
|
|
R. A. Heil-Chapdelaine, N. K. Tran, and J. A. Cooper Dynein-dependent Movements of the Mitotic Spindle in Saccharomyces cerevisiae Do Not Require Filamentous Actin Mol. Biol. Cell, March 1, 2000; 11(3): 863 - 872. [Abstract] [Full Text]
|
|
|
|
|
|
T. Nguyen, H Sawa, H Okano, and J. White The C. elegans septin genes, unc-59 and unc-61, are required for normal postembryonic cytokineses and morphogenesis but have no essential function in embryogenesis J. Cell Sci., January 11, 2000; 113(21): 3825 - 3837. [Abstract] [PDF]
|
|
|
|
|
|
P. Gonczy, S. Pichler, M. Kirkham, and A. A. Hyman Cytoplasmic Dynein Is Required for Distinct Aspects of Mtoc Positioning, Including Centrosome Separation, in the One Cell Stage Caenorhabditis elegans Embryo J. Cell Biol., October 4, 1999; 147(1): 135 - 150. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. McCartney, H. A. Dierick, C. Kirkpatrick, M. M. Moline, A. Baas, M. Peifer, and A. Bejsovec Drosophila Apc2 Is a Cytoskeletally-Associated Protein That Regulates Wingless Signaling in the Embryonic Epidermis J. Cell Biol., September 20, 1999; 146(6): 1303 - 1318. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Schlesinger, C. A. Shelton, J. N. Maloof, M. Meneghini, and B. Bowerman Wnt pathway components orient a mitotic spindle in the early Caenorhabditis elegans embryo without requiring gene transcription in the responding cell Genes & Dev., August 1, 1999; 13(15): 2028 - 2038. [Abstract] [Full Text]
|
|
|
|
|
|
R. A. Heil-Chapdelaine, N. R. Adames, and J. A. Cooper Formin' the Connection between Microtubules and the Cell Cortex J. Cell Biol., March 8, 1999; 144(5): 809 - 811. [Full Text] [PDF]
|
|
|
|
 |
|
 J. , B. E. , R. , B. , and A. The cytoplast concept in dividing plant cells: cytoplasmic domains and the evolution of spatially organized cell Am. J. Botany, February 1, 1999; 86(2): 153 - 172. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K Gallagher and L. Smith discordia mutations specifically misorient asymmetric cell divisions during development of the maize leaf epidermis Development, January 10, 1999; 126(20): 4623 - 4633. [Abstract] [PDF]
|
|
|
|
|
|
S. Miller and D. Kirk glsA, a Volvox gene required for asymmetric division and germ cell specification, encodes a chaperone-like protein Development, January 2, 1999; 126(4): 649 - 658. [Abstract] [PDF]
|
|
|
|
|
|
K. F. O'Connell, C. M. Leys, and J. G. White A Genetic Screen for Temperature-Sensitive Cell-Division Mutants of Caenorhabditis elegans Genetics, July 1, 1998; 149(3): 1303 - 1321. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Lowin-Kropf, V. S. Shapiro, and A. Weiss Cytoskeletal Polarization of T Cells Is Regulated by an Immunoreceptor Tyrosine-based Activation Motif-dependent Mechanism J. Cell Biol., February 23, 1998; 140(4): 861 - 871. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. G. Giansanti, S. Bonaccorsi, B. Williams, E. V. Williams, C. Santolamazza, M. L. Goldberg, and M. Gatti Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis Genes & Dev., February 1, 1998; 12(3): 396 - 410. [Abstract] [Full Text]
|
|
|
|
|
|
H. Keating and J. White Centrosome dynamics in early embryos of Caenorhabditis elegans J. Cell Sci., January 10, 1998; 111(20): 3027 - 3033. [Abstract] [PDF]
|
|
|
|
|
|
S Reinsch and P Gonczy Mechanisms of nuclear positioning J. Cell Sci., January 8, 1998; 111(16): 2283 - 2295. [Abstract] [PDF]
|
|
|
|
|
|
L. Rose and K Kemphues The let-99 gene is required for proper spindle orientation during cleavage of the C. elegans embryo Development, January 4, 1998; 125(7): 1337 - 1346. [Abstract] [PDF]
|
|
|
|
|
|
T. Stearns Motoring to the Finish: Kinesin and Dynein Work Together to Orient the Yeast Mitotic Spindle J. Cell Biol., September 8, 1997; 138(5): 957 - 960. [Full Text] [PDF]
|
|
|
|
|
|
F. R. Cottingham and M. A. Hoyt Mitotic Spindle Positioning in Saccharomyces cerevisiae Is Accomplished by Antagonistically Acting Microtubule Motor Proteins J. Cell Biol., September 8, 1997; 138(5): 1041 - 1053. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Carminati and T. Stearns Microtubules Orient the Mitotic Spindle in Yeast through Dynein-dependent Interactions with the Cell Cortex J. Cell Biol., August 11, 1997; 138(3): 629 - 641. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. J. Adams Metaphase Spindles Rotate in the Neuroepithelium of Rat Cerebral Cortex J. Neurosci., December 1, 1996; 16(23): 7610 - 7618. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. F. Dillman III, L. P. Dabney, S. Karki, B. M. Paschal, E. L. F. Holzbaur, and K. K. Pfister Functional Analysis of Dynactin and Cytoplasmic Dynein in Slow Axonal Transport J. Neurosci., November 1, 1996; 16(21): 6742 - 6752. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L Boyd, S Guo, D Levitan, D. Stinchcomb, and K. Kemphues PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos Development, January 10, 1996; 122(10): 3075 - 3084. [Abstract] [PDF]
|
|
|
|
|
|
J. Watts, B Etemad-Moghadam, S Guo, L Boyd, B. Draper, C. Mello, J. Priess, and K. Kemphues par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3 Development, January 10, 1996; 122(10): 3133 - 3140. [Abstract] [PDF]
|
|
|
|
|
|
S. Hird, J. Paulsen, and S Strome Segregation of germ granules in living Caenorhabditis elegans embryos: cell-type-specific mechanisms for cytoplasmic localisation Development, January 4, 1996; 122(4): 1303 - 1312. [Abstract] [PDF]
|
|
|
|
|
|
J. P. Aumais, J. R. Tunstead, R. S. McNeil, B. T. Schaar, S. K. McConnell, S.-H. Lin, G. D. Clark, and L.-y. Yu-Lee NudC Associates with Lis1 and the Dynein Motor at the Leading Pole of Neurons J. Neurosci., December 15, 2001; 21(24): RC187 - RC187. [Abstract] [Full Text] [PDF]
|
|
