|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 120, Issue 9 2637-2649, Copyright © 1994 by Company of Biologists
JOURNAL ARTICLES |
A Kurtz, A Zimmer, F Schnutgen, G Bruning, F Spener and T Muller
Unit on Developmental Biology, National Institute of Mental Health, Bethesda, MD 20892.
Fatty acid binding proteins (FABPs) are a multigene family of small intracellular proteins that bind hydrophobic ligands. In this report we describe the cloning and expression pattern of a novel member of this gene family that is specifically expressed in the developing and adult nervous system and thus was designated brain (B)-FABP. B-FABP is closely related to heart (H)-FABP with 67% amino acid identity. B-FABP expression was first detected at mouse embryonic day 10 in neuroepithelial cells and its pattern correlates with early neuronal differentiation. Upon further development, B-FABP was confined to radial glial cells and immature astrocytes. B-FABP mRNA and protein were found in glial cells of the peripheral nervous system such as satellite cells of spinal and cranial ganglia and ensheathing cells of the olfactory nerve layer from as early as embryonic day 11 until adulthood. In the adult mouse brain, B-FABP was found in the glia limitans, in radial glial cells of the hippocampal dentate gyrus and Bergman glial cells. These findings suggest a function of B-FABP during neurogenesis or neuronal migration in the developing nervous system. The partially overlapping expression pattern with that of cellular retinoid binding proteins suggests that B-FABP is involved in the metabolism of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  M. A. Breau, A. Dahmani, F. Broders-Bondon, J.-P. Thiery, and S. Dufour {beta}1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells Development, August 15, 2009; 136(16): 2791 - 2801. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-T. Liu, Y.-H. Kuan, J. Wang, R. Hen, and M. D. Gershon 5-HT4 Receptor-Mediated Neuroprotection and Neurogenesis in the Enteric Nervous System of Adult Mice J. Neurosci., August 5, 2009; 29(31): 9683 - 9699. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Kaczocha, S. T. Glaser, and D. G. Deutsch Identification of intracellular carriers for the endocannabinoid anandamide PNAS, April 14, 2009; 106(15): 6375 - 6380. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Causeret, M. Terao, T. Jacobs, Y. V. Nishimura, Y. Yanagawa, K. Obata, M. Hoshino, and M. Nikolic The p21-Activated Kinase Is Required for Neuronal Migration in the Cerebral Cortex Cereb Cortex, April 1, 2009; 19(4): 861 - 875. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. K. Singh, S. Gupta, Y. Jiang, M. Younus, and M. Ramzan In vitro Neurogenesis from Neural Progenitor Cells Isolated from the Hippocampus Region of the Brain of Adult Rats Exposed to Ethanol during Early Development through Their Alcohol-Drinking Mothers Alcohol Alcohol., March 1, 2009; 44(2): 185 - 198. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Guan, J. F. Williams, and R. P. Ricciardi Induction of Neuronal and Tumor-Related Genes by Adenovirus Type 12 E1A J. Virol., January 15, 2009; 83(2): 651 - 661. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Bogni, P. Trainor, D. Natarajan, R. Krumlauf, and V. Pachnis Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis Development, September 15, 2008; 135(18): 3007 - 3011. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Bondurand, D. Natarajan, A. Barlow, N. Thapar, and V. Pachnis Maintenance of mammalian enteric nervous system progenitors by SOX10 and endothelin 3 signalling Development, May 15, 2006; 133(10): 2075 - 2086. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Goto, Y. Matsuzaki, S. Kurihara, A. Shimizu, T. Okada, K. Yamamoto, H. Murata, M. Takata, H. Aburatani, D. S.B. Hoon, et al. A new melanoma antigen Fatty Acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res., April 15, 2006; 66(8): 4443 - 4449. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Luzzati, S. De Marchis, A. Fasolo, and P. Peretto Neurogenesis in the Caudate Nucleus of the Adult Rabbit J. Neurosci., January 11, 2006; 26(2): 609 - 621. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Zhu, T. Harada, L. Liu, M. E. Lush, F. Guignard, C. Harada, D. K. Burns, M. L. Bajenaru, D. H. Gutmann, and L. F. Parada Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation Development, December 15, 2005; 132(24): 5577 - 5588. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Arai, N. Funatsu, K. Numayama-Tsuruta, T. Nomura, S. Nakamura, and N. Osumi Role of Fabp7, a Downstream Gene of Pax6, in the Maintenance of Neuroepithelial Cells during Early Embryonic Development of the Rat Cortex J. Neurosci., October 19, 2005; 25(42): 9752 - 9761. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. E. Anthony, H. A. Mason, T. Gridley, G. Fishell, and N. Heintz Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells Genes & Dev., May 1, 2005; 19(9): 1028 - 1033. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. M.A.L. Pelsers, T. Hanhoff, D. Van der Voort, B. Arts, M. Peters, R. Ponds, A. Honig, W. Rudzinski, F. Spener, J. R. de Kruijk, et al. Brain- and Heart-Type Fatty Acid-Binding Proteins in the Brain: Tissue Distribution and Clinical Utility Clin. Chem., September 1, 2004; 50(9): 1568 - 1575. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U. Gurok, C. Steinhoff, B. Lipkowitz, H.-H. Ropers, C. Scharff, and U. A. Nuber Gene Expression Changes in the Course of Neural Progenitor Cell Differentiation J. Neurosci., June 30, 2004; 24(26): 5982 - 6002. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. G. Zimmermann-Ivol, P. R. Burkhard, J. Le Floch-Rohr, L. Allard, D. F. Hochstrasser, and J.-C. Sanchez Fatty Acid Binding Protein as a Serum Marker for the Early Diagnosis of Stroke: A Pilot Study Mol. Cell. Proteomics, January 1, 2004; 3(1): 66 - 72. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. B. Genter, P. P. Van Veldhoven, A. G. Jegga, B. Sakthivel, S. Kong, K. Stanley, D. P. Witte, C. L. Ebert, and B. J. Aronow Microarray-based discovery of highly expressed olfactory mucosal genes: potential roles in the various functions of the olfactory system Physiol Genomics, December 16, 2003; 16(1): 67 - 81. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Hartfuss, E. Forster, H. H. Bock, M. A. Hack, P. Leprince, J. M. Luque, J. Herz, M. Frotscher, and M. Gotz Reelin signaling directly affects radial glia morphology and biochemical maturation Development, October 1, 2003; 130(19): 4597 - 4609. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Shu, Y. Li, A. Keller, and L. J. Richards The glial sling is a migratory population of developing neurons Development, July 1, 2003; 130(13): 2929 - 2937. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. F. Sanchez-Font, A. Bosch-Comas, R. Gonzalez-Duarte, and G. Marfany Overexpression of FABP7 in Down syndrome fetal brains is associated with PKNOX1 gene-dosage imbalance Nucleic Acids Res., June 1, 2003; 31(11): 2769 - 2777. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. J. Miller, H. Li, T. A. Rizvi, Y. Huang, G. Johansson, J. Bowersock, A. Sidani, J. Vitullo, K. Vogel, L. M. Parysek, et al. Brain Lipid Binding Protein in Axon-Schwann Cell Interactions and Peripheral Nerve Tumorigenesis Mol. Cell. Biol., March 15, 2003; 23(6): 2213 - 2224. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Shu, K. G. Butz, C. Plachez, R. M. Gronostajski, and L. J. Richards Abnormal Development of Forebrain Midline Glia and Commissural Projections in Nfia Knock-Out Mice J. Neurosci., January 1, 2003; 23(1): 203 - 212. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Sugitani, S. Nakai, O. Minowa, M. Nishi, K.-i. Jishage, H. Kawano, K. Mori, M. Ogawa, and T. Noda Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons Genes & Dev., July 15, 2002; 16(14): 1760 - 1765. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Lonigro, D. Donnini, E. Zappia, G. Damante, M. E. Bianchi, and S. Guazzi Nestin Is a Neuroepithelial Target Gene of Thyroid Transcription Factor-1, a Homeoprotein Required for Forebrain Organogenesis J. Biol. Chem., December 14, 2001; 276(51): 47807 - 47813. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Sharon, M. S. Goldberg, I. Bar-Josef, R. A. Betensky, J. Shen, and D. J. Selkoe alpha -Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins PNAS, July 31, 2001; 98(16): 9110 - 9115. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Britsch, D. E. Goerich, D. Riethmacher, R. I. Peirano, M. Rossner, K.-A. Nave, C. Birchmeier, and M. Wegner The transcription factor Sox10 is a key regulator of peripheral glial development Genes & Dev., January 1, 2001; 15(1): 66 - 78. [Abstract] [Full Text]
|
|
|
|
|
|
P. Sundaresan, W. D. Hunter, R. L. Martuza, and S. D. Rabkin Attenuated, Replication-Competent Herpes Simplex Virus Type 1 Mutant G207: Safety Evaluation in Mice J. Virol., April 15, 2000; 74(8): 3832 - 3841. [Abstract] [Full Text]
|
|
|
|
|
|
P Malatesta, E Hartfuss, and M Gotz Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage Development, January 12, 2000; 127(24): 5253 - 5263. [Abstract] [PDF]
|
|
|
|
|
|
K. J. Chandross, R. I. Cohen, P. Paras Jr, M. Gravel, P. E. Braun, and L. D. Hudson Identification and Characterization of Early Glial Progenitors Using a Transgenic Selection Strategy J. Neurosci., January 15, 1999; 19(2): 759 - 774. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Britsch, L. Li, S. Kirchhoff, F. Theuring, V. Brinkmann, C. Birchmeier, and D. Riethmacher The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system Genes & Dev., June 15, 1998; 12(12): 1825 - 1836. [Abstract] [Full Text]
|
|
|
|
|
|
R Josephson, T Muller, J Pickel, S Okabe, K Reynolds, P. Turner, A Zimmer, and R. McKay POU transcription factors control expression of CNS stem cell-specific genes Development, January 8, 1998; 125(16): 3087 - 3100. [Abstract] [PDF]
|
|
|
|
|
|
O. Brustle, A. C. Spiro, K. Karram, K. Choudhary, S. Okabe, and R. D. G. McKay In vitro-generated neural precursors participate in mammalian brain development PNAS, December 23, 1997; 94(26): 14809 - 14814. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. MacNeill, B. Ayres, A. C. Laverriere, and J. B.E. Burch Transcripts for Functionally Distinct Isoforms of Chicken GATA-5 Are Differentially Expressed from Alternative First Exons J. Biol. Chem., March 28, 1997; 272(13): 8396 - 8401. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Anton, M. Marchionni, K. Lee, and P Rakic Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex Development, January 9, 1997; 124(18): 3501 - 3510. [Abstract] [PDF]
|
|
|
|
|
|
L. Z. Xu, R. Sanchez, A. Sali, and N. Heintz Ligand Specificity of Brain Lipid-binding Protein J. Biol. Chem., October 4, 1996; 271(40): 24711 - 24719. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Specht, N. Bartetzko, C. Hohoff, H. Kuhl, R. Franke, T. Borchers, and F. Spener Mammary Derived Growth Inhibitor Is Not a Distinct Protein but a Mix of Heart-type and Adipocyte-type Fatty Acid-binding Protein J. Biol. Chem., August 16, 1996; 271(33): 19943 - 19949. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. S. Mosallam Connection and Reinforcement Design Details for Pultruded Fiber Reinforced Plastic (PFRP) Composite Structures Journal of Reinforced Plastics and Composites, July 1, 1995; 14(7): 752 - 784. [Abstract]
|
|
|
|
|
|
L Feng and N Heintz Differentiating neurons activate transcription of the brain lipid-binding protein gene in radial glia through a novel regulatory element Development, January 6, 1995; 121(6): 1719 - 1730. [Abstract] [PDF]
|
|
|
|
|
|
G. K. Balendiran, F. Schnutgen, G. Scapin, T. Borchers, N. Xhong, K. Lim, R. Godbout, F. Spener, and J. C. Sacchettini Crystal Structure and Thermodynamic Analysis of Human Brain Fatty Acid-binding Protein J. Biol. Chem., August 25, 2000; 275(35): 27045 - 27054. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Bisgrove, E. A. Monckton, M. Packer, and R. Godbout Regulation of Brain Fatty Acid-binding Protein Expression by Differential Phosphorylation of Nuclear Factor I in Malignant Glioma Cell Lines J. Biol. Chem., September 22, 2000; 275(39): 30668 - 30676. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Montell, C. Lerin, C. B. Newgard, and A. M. Gomez-Foix Effects of Modulation of Glycerol Kinase Expression on Lipid and Carbohydrate Metabolism in Human Muscle Cells J. Biol. Chem., January 18, 2002; 277(4): 2682 - 2686. [Abstract] [Full Text] [PDF]
|
|
