|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 121, Issue 11 3675-3686, Copyright © 1995 by Company of Biologists
JOURNAL ARTICLES |
HM Stern, AM Brown and SD Hauschka
University of Washington, Department of Biochemistry, Seattle, WA 98195, USA.
Previous studies have demonstrated that the neural tube/notochord complex is required for skeletal muscle development within somites. In order to explore the localization of myogenic inducing signals within the neural tube, dorsal or ventral neural tube halves were cultured in contact with single somites or pieces of segmental plate mesoderm. Somites and segmental plates cultured with the dorsal half of the neural tube exhibited 70% and 85% myogenic response rates, as determined by immunostaining for myosin heavy chain. This response was slightly lower than the 100% response to whole neural tube/notochord, but was much greater than the 30% and 10% myogenic response to ventral neural tube with and without notochord. These results demonstrate that the dorsal neural tube emits a potent myogenic inducing signal which accounts for most of the inductive activity of whole neural tube/notochord. However, a role for ventral neural tube/notochord in somite myogenic induction was clearly evident from the larger number of myogenic cells induced when both dorsal neural tube and ventral neural tube/notochord were present. To address the role of a specific dorsal neural tube factor in somite myogenic induction, we tested the ability of Wnt-1-expressing fibroblasts to promote paraxial mesoderm myogenesis in vitro. We found that cells expressing Wnt-1 induced a small number of somite and segmental plate cells to undergo myogenesis. This finding is consistent with the localized dorsal neural tube inductive activity described above, but since the ventral neural tube/notochord also possesses myogenic inductive capacity yet does not express Wnt-1, additional inductive factors are likely involved.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  R. Piran, E. Halperin, N. Guttmann-Raviv, E. Keinan, and R. Reshef Algorithm of myogenic differentiation in higher-order organisms Development, November 15, 2009; 136(22): 3831 - 3840. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. F. Tong, X. Yan, M. J. Zhu, S. P. Ford, P. W. Nathanielsz, and M. Du Maternal obesity downregulates myogenesis and {beta}-catenin signaling in fetal skeletal muscle Am J Physiol Endocrinol Metab, April 1, 2009; 296(4): E917 - E924. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Otto, C. Schmidt, G. Luke, S. Allen, P. Valasek, F. Muntoni, D. Lawrence-Watt, and K. Patel Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration J. Cell Sci., September 1, 2008; 121(17): 2939 - 2950. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Gerhart, J. Elder, C. Neely, J. Schure, T. Kvist, K. Knudsen, and M. George-Weinstein MyoD-positive epiblast cells regulate skeletal muscle differentiation in the embryo J. Cell Biol., October 23, 2006; 175(2): 283 - 292. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Tirosh-Finkel, H. Elhanany, A. Rinon, and E. Tzahor Mesoderm progenitor cells of common origin contribute to the head musculature and the cardiac outflow tract Development, May 15, 2006; 133(10): 1943 - 1953. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Linker, C. Lesbros, J. Gros, L. W. Burrus, A. Rawls, and C. Marcelle {beta}-Catenin-dependent Wnt signalling controls the epithelial organisation of somites through the activation of paraxis Development, September 1, 2005; 132(17): 3895 - 3905. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. M. Vertino, J. M. Taylor-Jones, K. A. Longo, E. D. Bearden, T. F. Lane, R. E. McGehee Jr., O. A. MacDougald, and C. A. Peterson Wnt10b Deficiency Promotes Coexpression of Myogenic and Adipogenic Programs in Myoblasts Mol. Biol. Cell, April 1, 2005; 16(4): 2039 - 2048. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Petropoulos, P. J. Gianakopoulos, A. G. Ridgeway, and I. S. Skerjanc Disruption of Meox or Gli Activity Ablates Skeletal Myogenesis in P19 Cells J. Biol. Chem., June 4, 2004; 279(23): 23874 - 23881. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. A. Hogan, C. A. Ambler, D. L. Chapman, and V. L. Bautch The neural tube patterns vessels developmentally using the VEGF signaling pathway Development, April 1, 2004; 131(7): 1503 - 1513. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Ahmed, S.-J. Du, N. O'Leary, and G. R. Vasta Biochemical and molecular characterization of galectins from zebrafish (Danio rerio): notochord-specific expression of a prototype galectin during early embryogenesis Glycobiology, March 1, 2004; 14(3): 219 - 232. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Tzahor, H. Kempf, R. C. Mootoosamy, A. C. Poon, A. Abzhanov, C. J. Tabin, S. Dietrich, and A. B. Lassar Antagonists of Wnt and BMP signaling promote the formation of vertebrate head muscle Genes & Dev., December 15, 2003; 17(24): 3087 - 3099. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Linker, C. Lesbros, M. R. Stark, and C. Marcelle Intrinsic signals regulate the initial steps of myogenesis in vertebrates Development, October 15, 2003; 130(20): 4797 - 4807. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. D. Sacks, G. M. Cann, W. Nikovits Jr, S. Conlon, N. R. Espinoza, and F. E. Stockdale Regulation of myosin expression during myotome formation Development, August 1, 2003; 130(15): 3391 - 3402. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Buchberger, N. Nomokonova, and H.-H. Arnold Myf5 expression in somites and limb buds of mouse embryos is controlled by two distinct distal enhancer activities Development, July 15, 2003; 130(14): 3297 - 3307. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Petropoulos and I. S. Skerjanc beta -Catenin Is Essential and Sufficient for Skeletal Myogenesis in P19 Cells J. Biol. Chem., May 3, 2002; 277(18): 15393 - 15399. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Borycki, A. M. Brown, and C. P. Emerson Shh and Wnt signaling pathways converge to control Gli gene activation in avian somites Development, May 15, 2000; 127(10): 2075 - 2087. [Abstract] [PDF]
|
|
|
|
|
|
M Schmidt, M Tanaka, and A Munsterberg Expression of (beta)-catenin in the developing chick myotome is regulated by myogenic signals Development, January 10, 2000; 127(19): 4105 - 4113. [Abstract] [PDF]
|
|
|
|
|
|
A Sukegawa, T Narita, T Kameda, K Saitoh, T Nohno, H Iba, S Yasugi, and K Fukuda The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium Development, January 5, 2000; 127(9): 1971 - 1980. [Abstract] [PDF]
|
|
|
|
|
|
L Mathis and J. Nicolas Different clonal dispersion in the rostral and caudal mouse central nervous system Development, January 3, 2000; 127(6): 1277 - 1290. [Abstract] [PDF]
|
|
|
|
|
|
W. Denetclaw and C. Ordahl The growth of the dermomyotome and formation of early myotome lineages in thoracolumbar somites of chicken embryos Development, January 2, 2000; 127(4): 893 - 905. [Abstract] [PDF]
|
|
|
|
|
|
L. C. Murtaugh, J. H. Chyung, and A. B. Lassar Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling Genes & Dev., January 15, 1999; 13(2): 225 - 237. [Abstract] [Full Text]
|
|
|
|
|
|
U Borello, M Coletta, S Tajbakhsh, L Leyns, E. De Robertis, M Buckingham, and G Cossu Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos Development, January 10, 1999; 126(19): 4247 - 4255. [Abstract] [PDF]
|
|
|
|
|
|
H Amthor, B Christ, and K Patel A molecular mechanism enabling continuous embryonic muscle growth - a balance between proliferation and differentiation Development, January 2, 1999; 126(5): 1041 - 1053. [Abstract] [PDF]
|
|
|
|
|
|
J.-S. Kang, P. J. Mulieri, C. Miller, D. A. Sassoon, and R. S. Krauss CDO, A Robo-related Cell Surface Protein that Mediates Myogenic Differentiation J. Cell Biol., October 19, 1998; 143(2): 403 - 413. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Kozopas, C. H. Samos, and R. Nusse DWnt-2, a Drosophila Wnt gene required for the development of the male reproductive tract, specifies a sexually dimorphic cell fate Genes & Dev., April 15, 1998; 12(8): 1155 - 1165. [Abstract] [Full Text]
|
|
|
|
|
|
R. Reshef, M. Maroto, and A. B. Lassar Regulation of dorsal somitic cell fates: BMPs and Noggin control the timing and pattern of myogenic regulator expression Genes & Dev., February 1, 1998; 12(3): 290 - 303. [Abstract] [Full Text]
|
|
|
|
|
|
S Tajbakhsh, U Borello, E Vivarelli, R Kelly, J Papkoff, D Duprez, M Buckingham, and G Cossu Differential activation of Myf5 and MyoD by different Wnts in explants of mouse paraxial mesoderm and the later activation of myogenesis in the absence of Myf5 Development, January 11, 1998; 125(21): 4155 - 4162. [Abstract] [PDF]
|
|
|
|
|
|
N Kahane, Y Cinnamon, and C Kalcheim The cellular mechanism by which the dermomyotome contributes to the second wave of myotome development Development, January 11, 1998; 125(21): 4259 - 4271. [Abstract] [PDF]
|
|
|
|
|
|
M Teillet, Y Watanabe, P Jeffs, D Duprez, F Lapointe, and N. Le Douarin Sonic hedgehog is required for survival of both myogenic and chondrogenic somitic lineages Development, January 6, 1998; 125(11): 2019 - 2030. [Abstract] [PDF]
|
|
|
|
|
|
C. S. Blagden, P. D. Currie, P. W. Ingham, and S. M. Hughes Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog Genes & Dev., September 1, 1997; 11(17): 2163 - 2175. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Williams and C. Ordahl Emergence of determined myotome precursor cells in the somite Development, January 12, 1997; 124(24): 4983 - 4997. [Abstract] [PDF]
|
|
|
|
|
|
E Hirsinger, D Duprez, C Jouve, P Malapert, J Cooke, and O Pourquie Noggin acts downstream of Wnt and Sonic Hedgehog to antagonize BMP4 in avian somite patterning Development, January 11, 1997; 124(22): 4605 - 4614. [Abstract] [PDF]
|
|
|
|
|
|
S Dietrich, F. Schubert, and A Lumsden Control of dorsoventral pattern in the chick paraxial mesoderm Development, January 10, 1997; 124(19): 3895 - 3908. [Abstract] [PDF]
|
|
|
|
|
|
C Marcelle, M. Stark, and M Bronner-Fraser Coordinate actions of BMPs, Wnts, Shh and noggin mediate patterning of the dorsal somite Development, January 10, 1997; 124(20): 3955 - 3963. [Abstract] [PDF]
|
|
|
|
|
|
H. Stern, J Lin-Jones, and S. Hauschka Synergistic interactions between bFGF and a TGF-beta family member may mediate myogenic signals from the neural tube Development, January 9, 1997; 124(18): 3511 - 3523. [Abstract] [PDF]
|
|
|
|
|
|
J Fontaine-Perus, P Halgand, Y Cheraud, T Rouaud, M. Velasco, C Cifuentes Diaz, and F Rieger Mouse-chick chimera: a developmental model of murine neurogenic cells Development, January 8, 1997; 124(16): 3025 - 3036. [Abstract] [PDF]
|
|
|
|
|
|
S Hoppler, J D Brown, and R T Moon Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos. Genes & Dev., November 1, 1996; 10(21): 2805 - 2817. [Abstract] [PDF]
|
|
|
|
|
|
A E Munsterberg, J Kitajewski, D A Bumcrot, A P McMahon, and A B Lassar Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes & Dev., December 1, 1995; 9(23): 2911 - 2922. [Abstract] [PDF]
|
|
|
|
|
|
A. G. Ridgeway, H. Petropoulos, S. Wilton, and I. S. Skerjanc Wnt Signaling Regulates the Function of MyoD and Myogenin J. Biol. Chem., October 13, 2000; 275(42): 32398 - 32405. [Abstract] [Full Text] [PDF]
|
|
