spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zhang, H.
Right arrow Articles by Bradley, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhang, H.
Right arrow Articles by Bradley, A.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Development, Vol 122, Issue 10 2977-2986, Copyright © 1996 by Company of Biologists


JOURNAL ARTICLES

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

H Zhang and A Bradley
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.

To address the function of bone morphogenetic protein-2 (BMP2) in mammalian development, mice with a targeted deletion of the Bmp2 mature region were generated using embryonic stem cell technology. This mutation caused embryonic lethality when homozygous. Mutant embryos failed to close the proamniotic canal, which caused the malformation of the amnion/chorion. BMP2-deficient embryos also exhibited a defect in cardiac development, manifested by the abnormal development of the heart in the exocoelomic cavity. These defects are consistent with the expression of Bmp2 in the extraembryonic mesoderm cells and promyocardium. Thus BMP2 is a critical factor for both extraembryonic and embryonic development.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
A. Nomura-Kitabayashi, C. K. L. Phoon, S. Kishigami, J. Rosenthal, Y. Yamauchi, K. Abe, K.-i. Yamamura, R. Samtani, C. W. Lo, and Y. Mishina
Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest
Am J Physiol Heart Circ Physiol, November 1, 2009; 297(5): H1617 - H1628.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
M. A. Edson, A. K. Nagaraja, and M. M. Matzuk
The Mammalian Ovary from Genesis to Revelation
Endocr. Rev., October 1, 2009; 30(6): 624 - 712.
[Abstract] [Full Text] [PDF]


Home page
Hum Mol GenetHome page
R. Dobrowolski, G. Hertig, H. Lechner, P. Worsdorfer, V. Wulf, N. Dicke, D. Eckert, R. Bauer, H. Schorle, and K. Willecke
Loss of connexin43-mediated gap junctional coupling in the mesenchyme of limb buds leads to altered expression of morphogens in mice
Hum. Mol. Genet., August 1, 2009; 18(15): 2899 - 2911.
[Abstract] [Full Text] [PDF]


Home page
Nephrol Dial TransplantHome page
J. Nystrom, K. Hultenby, S. Ek, J. Sjolund, H. Axelson, K. Jirstrom, M. A. Saleem, K. Nilsson, and M. E. Johansson
CRIM1 is localized to the podocyte filtration slit diaphragm of the adult human kidney
Nephrol. Dial. Transplant., July 1, 2009; 24(7): 2038 - 2044.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
X. Sui, D. Li, H. Qiu, V. Gaussin, and C. Depre
Activation of the Bone Morphogenetic Protein Receptor by H11Kinase/Hsp22 Promotes Cardiac Cell Growth and Survival
Circ. Res., April 10, 2009; 104(7): 887 - 895.
[Abstract] [Full Text] [PDF]


Home page
Hum Mol GenetHome page
M. Asai-Coakwell, C. R. French, M. Ye, K. Garcha, K. Bigot, A. G. Perera, K. Staehling-Hampton, S. C. Mema, B. Chanda, A. Mushegian, et al.
Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes
Hum. Mol. Genet., March 15, 2009; 18(6): 1110 - 1121.
[Abstract] [Full Text] [PDF]


Home page
J. Med. Genet.Home page
S R Lalani, J V Thakuria, G F Cox, X Wang, W Bi, M S Bray, C Shaw, S W Cheung, A C Chinault, B A Boggs, et al.
20p12.3 microdeletion predisposes to Wolff-Parkinson-White syndrome with variable neurocognitive deficits
J. Med. Genet., March 1, 2009; 46(3): 168 - 175.
[Abstract] [Full Text] [PDF]


Home page
JBJSHome page
P. A. Cole, T. Miclau III, T. V. Ly, J. A. Switzer, M. Li, R. A. Morgan, and M. Bhandari
What's New in Orthopaedic Trauma
J. Bone Joint Surg. Am., December 1, 2008; 90(12): 2804 - 2822.
[Full Text] [PDF]


Home page
DevelopmentHome page
N. Kamiya, L. Ye, T. Kobayashi, Y. Mochida, M. Yamauchi, H. M. Kronenberg, J. Q. Feng, and Y. Mishina
BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
Development, November 15, 2008; 135(22): 3801 - 3811.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. Liu, D. T. Fritz, M. B. Rogers, and A. J. Shatkin
Species-specific cis-Regulatory Elements in the 3'-Untranslated Region Direct Alternative Polyadenylation of Bone Morphogenetic Protein 2 mRNA
J. Biol. Chem., October 17, 2008; 283(42): 28010 - 28019.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. Harada, A. Ogai, T. Takahashi, M. Kitakaze, H. Matsubara, and H. Oh
Crossveinless-2 Controls Bone Morphogenetic Protein Signaling during Early Cardiomyocyte Differentiation in P19 Cells
J. Biol. Chem., September 26, 2008; 283(39): 26705 - 26713.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
T. Sumi, N. Tsuneyoshi, N. Nakatsuji, and H. Suemori
Defining early lineage specification of human embryonic stem cells by the orchestrated balance of canonical Wnt/{beta}-catenin, Activin/Nodal and BMP signaling
Development, September 1, 2008; 135(17): 2969 - 2979.
[Abstract] [Full Text] [PDF]


Home page
Vasc MedHome page
M. Zhang, S.-h. Zhou, S.-P. Zhao, Q.-m. Liu, X.-p. Li, and X.-Q. Shen
Irbesartan attenuates Ang II-induced BMP-2 expression in human umbilical vein endothelial cells
Vascular Medicine, August 1, 2008; 13(3): 239 - 245.
[Abstract] [PDF]


Home page
JCBHome page
K. Niessen, Y. Fu, L. Chang, P. A. Hoodless, D. McFadden, and A. Karsan
Slug is a direct Notch target required for initiation of cardiac cushion cellularization
J. Cell Biol., July 28, 2008; 182(2): 315 - 325.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
K. Niessen and A. Karsan
Notch Signaling in Cardiac Development
Circ. Res., May 23, 2008; 102(10): 1169 - 1181.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Crit. Care Med.Home page
H. H. Kariyawasam, G. Xanthou, J. Barkans, M. Aizen, A. B. Kay, and D. S. Robinson
Basal Expression of Bone Morphogenetic Protein Receptor Is Reduced in Mild Asthma
Am. J. Respir. Crit. Care Med., May 15, 2008; 177(10): 1074 - 1081.
[Abstract] [Full Text] [PDF]


Home page
J Am Coll CardiolHome page
J.-Y. Hahn, H.-J. Cho, H.-J. Kang, T.-S. Kim, M.-H. Kim, J.-H. Chung, J.-W. Bae, B.-H. Oh, Y.-B. Park, and H.-S. Kim
Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction.
J. Am. Coll. Cardiol., March 4, 2008; 51(9): 933 - 943.
[Abstract] [Full Text] [PDF]


Home page
JBJSHome page
K. Tsuji, K. Cox, A. Bandyopadhyay, B. D. Harfe, C. J. Tabin, and V. Rosen
BMP4 Is Dispensable for Skeletogenesis and Fracture-Healing in the Limb
J. Bone Joint Surg. Am., February 1, 2008; 90(Supplement_1): 14 - 18.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
X. Pi, R. Ren, R. Kelley, C. Zhang, M. Moser, A. B. Bohil, M. DiVito, R. E. Cheney, and C. Patterson
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptors
J. Cell Biol., December 31, 2007; 179(7): 1569 - 1582.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
S. Ohta, K. Suzuki, K. Tachibana, H. Tanaka, and G. Yamada
Cessation of gastrulation is mediated by suppression of epithelial-mesenchymal transition at the ventral ectodermal ridge
Development, December 15, 2007; 134(24): 4315 - 4324.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
A. Di-Gregorio, M. Sancho, D. W. Stuckey, L. A. Crompton, J. Godwin, Y. Mishina, and T. A. Rodriguez
BMP signalling inhibits premature neural differentiation in the mouse embryo
Development, September 15, 2007; 134(18): 3359 - 3369.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
Z. I. Ungvari
Endothelium-Derived Bone Morphogenic Protein Antagonists May Counteract the Proatherogenic Vascular Effects of Bone Morphogenic Protein 4
Circulation, September 11, 2007; 116(11): 1221 - 1223.
[Full Text] [PDF]


Home page
DevelopmentHome page
P. Ybot-Gonzalez, C. Gaston-Massuet, G. Girdler, J. Klingensmith, R. Arkell, N. D. E. Greene, and A. J. Copp
Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling
Development, September 1, 2007; 134(17): 3203 - 3211.
[Abstract] [Full Text] [PDF]


Home page
Sci SignalHome page
K. Kitisin, T. Saha, T. Blake, N. Golestaneh, M. Deng, C. Kim, Y. Tang, K. Shetty, B. Mishra, and L. Mishra
TGF-beta Signaling in Development
Sci. Signal., August 14, 2007; 2007(399): cm1 - cm1.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
K. Y. Lee, J.-W. Jeong, J. Wang, L. Ma, J. F. Martin, S. Y. Tsai, J. P. Lydon, and F. J. DeMayo
Bmp2 Is Critical for the Murine Uterine Decidual Response
Mol. Cell. Biol., August 1, 2007; 27(15): 5468 - 5478.
[Abstract] [Full Text] [PDF]


Home page
GutHome page
K. Kinoshita, Y. Iimuro, K. Otogawa, S. Saika, Y. Inagaki, Y. Nakajima, N. Kawada, J. Fujimoto, S. L Friedman, and K. Ikeda
Adenovirus-mediated expression of BMP-7 suppresses the development of liver fibrosis in rats
Gut, May 1, 2007; 56(5): 706 - 714.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
B. van Wijk, A. F.M. Moorman, and M. J.B. van den Hoff
Role of bone morphogenetic proteins in cardiac differentiation
Cardiovasc Res, May 1, 2007; 74(2): 244 - 255.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
Y.-X. Wang, L.-X. Qian, D. Liu, L.-L. Yao, Q. Jiang, Z. Yu, Y.-H. Gui, T. P. Zhong, and H.-Y. Song
Bone morphogenetic protein-2 acts upstream of myocyte-specific enhancer factor 2a to control embryonic cardiac contractility
Cardiovasc Res, May 1, 2007; 74(2): 290 - 303.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
R. L. Chandler, K. J. Chandler, K. A. McFarland, and D. P. Mortlock
Bmp2 Transcription in Osteoblast Progenitors Is Regulated by a Distant 3' Enhancer Located 156.3 Kilobases from the Promoter
Mol. Cell. Biol., April 15, 2007; 27(8): 2934 - 2951.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
A. Csiszar, N. Labinskyy, K. E. Smith, A. Rivera, E. N.T.P. Bakker, H. Jo, J. Gardner, Z. Orosz, and Z. Ungvari
Downregulation of Bone Morphogenetic Protein 4 Expression in Coronary Arterial Endothelial Cells: Role of Shear Stress and the cAMP/Protein Kinase A Pathway
Arterioscler Thromb Vasc Biol, April 1, 2007; 27(4): 776 - 782.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
H. Kokubo, S. Tomita-Miyagawa, Y. Hamada, and Y. Saga
Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2
Development, February 15, 2007; 134(4): 747 - 755.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
A. T. Naito, I. Shiojima, H. Akazawa, K. Hidaka, T. Morisaki, A. Kikuchi, and I. Komuro
Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis
PNAS, December 26, 2006; 103(52): 19812 - 19817.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
S. Singbrant, J. L. Moody, U. Blank, G. Karlsson, L. Umans, A. Zwijsen, and S. Karlsson
Smad5 is dispensable for adult murine hematopoiesis
Blood, December 1, 2006; 108(12): 3707 - 3712.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
N. Fukui, Y. Ikeda, T. Ohnuki, A. Hikita, S. Tanaka, S. Yamane, R. Suzuki, L. J. Sandell, and T. Ochi
Pro-inflammatory Cytokine Tumor Necrosis Factor-{alpha} Induces Bone Morphogenetic Protein-2 in Chondrocytes via mRNA Stabilization and Transcriptional Up-regulation
J. Biol. Chem., September 15, 2006; 281(37): 27229 - 27241.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
E. A. Bosman, K. A. Lawson, J. Debruyn, L. Beek, A. Francis, L. Schoonjans, D. Huylebroeck, and A. Zwijsen
Smad5 determines murine amnion fate through the control of bone morphogenetic protein expression and signalling levels
Development, September 1, 2006; 133(17): 3399 - 3409.
[Abstract] [Full Text] [PDF]


Home page
ReproductionHome page
R. L Jones, C. Stoikos, J. K Findlay, and L. A Salamonsen
TGF-{beta} superfamily expression and actions in the endometrium and placenta.
Reproduction, August 1, 2006; 132(2): 217 - 232.
[Abstract] [Full Text] [PDF]


Home page
Mol. Endocrinol.Home page
D. T. Fritz, S. Jiang, J. Xu, and M. B. Rogers
A Polymorphism in a Conserved Posttranscriptional Regulatory Motif Alters Bone Morphogenetic Protein 2 (BMP2) RNA:Protein Interactions
Mol. Endocrinol., July 1, 2006; 20(7): 1574 - 1586.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
K. Fukuda and S. Yuasa
Stem Cells as a Source of Regenerative Cardiomyocytes
Circ. Res., April 28, 2006; 98(8): 1002 - 1013.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Pathol.Home page
A. Csiszar, M. Ahmad, K. E. Smith, N. Labinskyy, Q. Gao, G. Kaley, J. G. Edwards, M. S. Wolin, and Z. Ungvari
Bone Morphogenetic Protein-2 Induces Proinflammatory Endothelial Phenotype
Am. J. Pathol., February 1, 2006; 168(2): 629 - 638.
[Abstract] [Full Text] [PDF]


Home page
Cancer Res.Home page
E. Ryschich, P. Lizdenis, C. Ittrich, A. Benner, S. Stahl, A. Hamann, J. Schmidt, P. Knolle, B. Arnold, G. J. Hammerling, et al.
Molecular Fingerprinting and Autocrine Growth Regulation of Endothelial Cells in a Murine Model of Hepatocellular Carcinoma
Cancer Res., January 1, 2006; 66(1): 198 - 211.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
L. Ma, M.-F. Lu, R. J. Schwartz, and J. F. Martin
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
Development, December 15, 2005; 132(24): 5601 - 5611.
[Abstract] [Full Text] [PDF]


Home page
Arterioscler. Thromb. Vasc. Bio.Home page
J.E. Ferguson III, R. W. Kelley, and C. Patterson
Mechanisms of Endothelial Differentiation in Embryonic Vasculogenesis
Arterioscler Thromb Vasc Biol, November 1, 2005; 25(11): 2246 - 2254.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
F. Kugimiya, H. Kawaguchi, S. Kamekura, H. Chikuda, S. Ohba, F. Yano, N. Ogata, T. Katagiri, Y. Harada, Y. Azuma, et al.
Involvement of Endogenous Bone Morphogenetic Protein (BMP) 2 and BMP6 in Bone Formation
J. Biol. Chem., October 21, 2005; 280(42): 35704 - 35712.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
C. C. Bleul and T. Boehm
BMP Signaling Is Required for Normal Thymus Development
J. Immunol., October 15, 2005; 175(8): 5213 - 5221.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
J. Wang, N. Xu, X. Feng, N. Hou, J. Zhang, X. Cheng, Y. Chen, Y. Zhang, and X. Yang
Targeted Disruption of Smad4 in Cardiomyocytes Results in Cardiac Hypertrophy and Heart Failure
Circ. Res., October 14, 2005; 97(8): 821 - 828.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
X. Chi, P. K. Chatterjee, W. Wilson III, S.-X. Zhang, F. J. DeMayo, and R. J. Schwartz
Complex cardiac Nkx2-5 gene expression activated by noggin-sensitive enhancers followed by chamber-specific modules
PNAS, September 20, 2005; 102(38): 13490 - 13495.
[Abstract] [Full Text] [PDF]


Home page
Circ. Res.Home page
K. A. Hruska, S. Mathew, and G. Saab
Bone Morphogenetic Proteins in Vascular Calcification
Circ. Res., July 22, 2005; 97(2): 105 - 114.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C.-L. Cai, W. Zhou, L. Yang, L. Bu, Y. Qyang, X. Zhang, X. Li, M. G. Rosenfeld, J. Chen, and S. Evans
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis
Development, May 15, 2005; 132(10): 2475 - 2487.
[Abstract] [Full Text] [PDF]


Home page
CirculationHome page
A. Csiszar, K. E. Smith, A. Koller, G. Kaley, J. G. Edwards, and Z. Ungvari
Regulation of Bone Morphogenetic Protein-2 Expression in Endothelial Cells: Role of Nuclear Factor-{kappa}B Activation by Tumor Necrosis Factor-{alpha}, H2O2, and High Intravascular Pressure
Circulation, May 10, 2005; 111(18): 2364 - 2372.
[Abstract] [Full Text] [PDF]


Home page
Physiol. GenomicsHome page
T. K. Zagranichnaya, X. Wu, A. M. Danos, and M. L. Villereal
Gene expression profiles in HEK-293 cells with low or high store-operated calcium entry: can regulatory as well as regulated genes be identified?
Physiol Genomics, March 21, 2005; 21(1): 14 - 33.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
R. Fiore, B. Rahim, V. M. Christoffels, A. F. M. Moorman, and A. W. Puschel
Inactivation of the Sema5a Gene Results in Embryonic Lethality and Defective Remodeling of the Cranial Vascular System
Mol. Cell. Biol., March 15, 2005; 25(6): 2310 - 2319.
[Abstract] [Full Text] [PDF]


Home page
ReproductionHome page
K. Y Lee and F. J DeMayo
Animal models of implantation
Reproduction, December 1, 2004; 128(6): 679 - 695.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. T. Fritz, D. Liu, J. Xu, S. Jiang, and M. B. Rogers
Conservation of Bmp2 Post-transcriptional Regulatory Mechanisms
J. Biol. Chem., November 19, 2004; 279(47): 48950 - 48958.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
W. M. Knosp, V. Scott, H. P. Bachinger, and H. S. Stadler
HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis
Development, September 15, 2004; 131(18): 4581 - 4592.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
R. M. Monteiro, S. M. C. de Sousa Lopes, O. Korchynskyi, P. t. Dijke, and C. L. Mummery
Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins
J. Cell Sci., September 15, 2004; 117(20): 4653 - 4663.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
V. Parekh, A. McEwen, V. Barbour, Y. Takahashi, J. E. Rehg, S. M. Jane, and J. M. Cunningham
Defective Extraembryonic Angiogenesis in Mice Lacking LBP-1a, a Member of the grainyhead Family of Transcription Factors
Mol. Cell. Biol., August 15, 2004; 24(16): 7113 - 7129.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
L. Mejia-Luna and G. Avila
Ca2+ channel regulation by transforming growth factor-{beta}1 and bone morphogenetic protein-2 in developing mice myotubes
J. Physiol., August 15, 2004; 559(1): 41 - 54.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
Y. Mishina, M. W. Starbuck, M. A. Gentile, T. Fukuda, V. Kasparcova, J. G. Seedor, M. C. Hanks, M. Amling, G. J. Pinero, S.-i. Harada, et al.
Bone Morphogenetic Protein Type IA Receptor Signaling Regulates Postnatal Osteoblast Function and Bone Remodeling
J. Biol. Chem., June 25, 2004; 279(26): 27560 - 27566.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Sudo, O. Avsian-Kretchmer, L. S. Wang, and A. J. W. Hsueh
Protein Related to DAN and Cerberus Is a Bone Morphogenetic Protein Antagonist That Participates in Ovarian Paracrine Regulation
J. Biol. Chem., May 28, 2004; 279(22): 23134 - 23141.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
R. W. Stottmann, M. Choi, Y. Mishina, E. N. Meyers, and J. Klingensmith
BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium
Development, May 1, 2004; 131(9): 2205 - 2218.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. L. Abrams, J. Xu, C. Nativelle-Serpentini, S. Dabirshahsahebi, and M. B. Rogers
An Evolutionary and Molecular Analysis of Bmp2 Expression
J. Biol. Chem., April 16, 2004; 279(16): 15916 - 15928.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
M. M. Shah, R. V. Sampogna, H. Sakurai, K. T. Bush, and S. K. Nigam
Branching morphogenesis and kidney disease
Development, April 1, 2004; 131(7): 1449 - 1462.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
A.-P. G. Haramis, H. Begthel, M. van den Born, J. van Es, S. Jonkheer, G. J. A. Offerhaus, and H. Clevers
De Novo Crypt Formation and Juvenile Polyposis on BMP Inhibition in Mouse Intestine
Science, March 12, 2004; 303(5664): 1684 - 1686.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
C. O. Brown III, X. Chi, E. Garcia-Gras, M. Shirai, X.-H. Feng, and R. J. Schwartz
The Cardiac Determination Factor, Nkx2-5, Is Activated by Mutual Cofactors GATA-4 and Smad1/4 via a Novel Upstream Enhancer
J. Biol. Chem., March 12, 2004; 279(11): 10659 - 10669.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
M. F. Pera, J. Andrade, S. Houssami, B. Reubinoff, A. Trounson, E. G. Stanley, D. W.-v. Oostwaard, and C. Mummery
Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin
J. Cell Sci., March 1, 2004; 117(7): 1269 - 1280.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
U. Guha, W. A. Gomes, J. Samanta, M. Gupta, F. L. Rice, and J. A. Kessler
Target-derived BMP signaling limits sensory neuron number and the extent of peripheral innervation in vivo
Development, March 1, 2004; 131(5): 1175 - 1186.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Pathol.Home page
M. Plikus, W. P. Wang, J. Liu, X. Wang, T.-X. Jiang, and C.-M. Chuong
Morpho-Regulation of Ectodermal Organs: Integument Pathology and Phenotypic Variations in K14-Noggin Engineered Mice through Modulation of Bone Morphogenic Protein Pathway
Am. J. Pathol., March 1, 2004; 164(3): 1099 - 1114.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
S. Shimasaki, R. K. Moore, F. Otsuka, and G. F. Erickson
The Bone Morphogenetic Protein System In Mammalian Reproduction
Endocr. Rev., February 1, 2004; 25(1): 72 - 101.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
T. Ueyama, H. Kasahara, T. Ishiwata, Q. Nie, and S. Izumo
Myocardin Expression Is Regulated by Nkx2.5, and Its Function Is Required for Cardiomyogenesis
Mol. Cell. Biol., December 15, 2003; 23(24): 9222 - 9232.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
B. C. J. van der Eerden, M. Karperien, and J. M. Wit
Systemic and Local Regulation of the Growth Plate
Endocr. Rev., December 1, 2003; 24(6): 782 - 801.
[Abstract] [Full Text] [PDF]


Home page
Physiol. Rev.Home page
A. F. M. MOORMAN and V. M. CHRISTOFFELS
Cardiac Chamber Formation: Development, Genes, and Evolution
Physiol Rev, October 1, 2003; 83(4): 1223 - 1267.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
M. Moser, O. Binder, Y. Wu, J. Aitsebaomo, R. Ren, C. Bode, V. L. Bautch, F. L. Conlon, and C. Patterson
BMPER, a Novel Endothelial Cell Precursor-Derived Protein, Antagonizes Bone Morphogenetic Protein Signaling and Endothelial Cell Differentiation
Mol. Cell. Biol., August 15, 2003; 23(16): 5664 - 5679.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
D. Bachiller, J. Klingensmith, N. Shneyder, U. Tran, R. Anderson, J. Rossant, and E. M. De Robertis
The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome
Development, August 1, 2003; 130(15): 3567 - 3578.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
M. C. Hu, T. D. Piscione, and N. D. Rosenblum
Elevated SMAD1/{beta}-catenin molecular complexes and renal medullary cystic dysplasia in ALK3 transgenic mice
Development, June 15, 2003; 130(12): 2753 - 2766.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
N. Ghosh-Choudhury, S. L. Abboud, L. Mahimainathan, B. Chandrasekar, and G. G. Choudhury
Phosphatidylinositol 3-Kinase Regulates Bone Morphogenetic Protein-2 (BMP-2)-induced Myocyte Enhancer Factor 2A-dependent Transcription of BMP-2 Gene in Cardiomyocyte Precursor Cells
J. Biol. Chem., June 6, 2003; 278(24): 21998 - 22005.
[Abstract] [Full Text] [PDF]


Home page
Cardiovasc ResHome page
M. J. Solloway and R. P. Harvey
Molecular pathways in myocardial development: a stem cell perspective
Cardiovasc Res, May 1, 2003; 58(2): 264 - 277.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
E. Canalis, A. N. Economides, and E. Gazzerro
Bone Morphogenetic Proteins, Their Antagonists, and the Skeleton
Endocr. Rev., April 1, 2003; 24(2): 218 - 235.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
A. Vogel-Hopker and H. Rohrer
The specification of noradrenergic locus coeruleus (LC) neurones depends on bone morphogenetic proteins (BMPs)
Development, March 4, 2003; 129(4): 983 - 991.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
C. A. Adelman, S. Chattopadhyay, and J. J. Bieker
The BMP/BMPR/Smad pathway directs expression of the erythroid-specific EKLF and GATA1 transcription factors during embryoid body differentiation in serum-free media
Development, March 3, 2003; 129(2): 539 - 549.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
E. C. Delot, M. E. Bahamonde, M. Zhao, and K. M. Lyons
BMP signaling is required for septation of the outflow tract of the mammalian heart
Development, January 1, 2003; 130(1): 209 - 220.
[Abstract] [Full Text] [PDF]


Home page
Endocr. Rev.Home page
H. Chang, C. W. Brown, and M. M. Matzuk
Genetic Analysis of the Mammalian Transforming Growth Factor-{beta} Superfamily
Endocr. Rev., December 1, 2002; 23(6): 787 - 823.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
A. L. Hager-Theodorides, S. V. Outram, D. K. Shah, R. Sacedon, R. E. Shrimpton, A. Vicente, A. Varas, and T. Crompton
Bone Morphogenetic Protein 2/4 Signaling Regulates Early Thymocyte Differentiation
J. Immunol., November 15, 2002; 169(10): 5496 - 5504.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
Z. Zhang, Y. Song, X. Zhao, X. Zhang, C. Fermin, and Y. Chen
Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a network of BMP and Shh signaling in the regulation of mammalian palatogenesis
Development, September 1, 2002; 129(17): 4135 - 4146.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Respir. Cell Mol. Bio.Home page
A. Rosendahl, E. Pardali, M. Speletas, P. ten Dijke, C.-H. Heldin, and P. Sideras
Activation of Bone Morphogenetic Protein/Smad Signaling in Bronchial Epithelial Cells during Airway Inflammation
Am. J. Respir. Cell Mol. Biol., August 1, 2002; 27(2): 160 - 169.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
P. S. Amieux, D. G. Howe, H. Knickerbocker, D. C. Lee, T. Su, G. S. Laszlo, R. L. Idzerda, and G. S. McKnight
Increased Basal cAMP-dependent Protein Kinase Activity Inhibits the Formation of Mesoderm-derived Structures in the Developing Mouse Embryo
J. Biol. Chem., July 19, 2002; 277(30): 27294 - 27304.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
M. Zhao, S. E. Harris, D. Horn, Z. Geng, R. Nishimura, G. R. Mundy, and Di Chen
Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation
J. Cell Biol., June 10, 2002; 157(6): 1049 - 1060.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
V. Gaussin, T. Van de Putte, Y. Mishina, M. C. Hanks, A. Zwijsen, D. Huylebroeck, R. R. Behringer, and M. D. Schneider
Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3
PNAS, February 14, 2002; (2002) 42390499.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
C. Thisse and L. I. Zon
Organogenesis--Heart and Blood Formation from the Zebrafish Point of View
Science, January 18, 2002; 295(5554): 457 - 462.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
R. M. Anderson, A. R. Lawrence, R. W. Stottmann, D. Bachiller, and J. Klingensmith
Chordin and noggin promote organizing centers of forebrain development in the mouse
Development, January 11, 2002; 129(21): 4975 - 4987.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
E. Minina, H. M. Wenzel, C. Kreschel, S. Karp, W. Gaffield, A. P. McMahon, and A. Vortkamp
BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation
Development, November 15, 2001; 128(22): 4523 - 4534.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
K. D. Tremblay, N. R. Dunn, and E. J. Robertson
Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation
Development, September 15, 2001; 128(18): 3609 - 3621.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
J. M. Rossi, N. R. Dunn, B. L.M. Hogan, and K. S. Zaret
Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm
Genes & Dev., August 1, 2001; 15(15): 1998 - 2009.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
K. Monzen, Y. Hiroi, S. Kudoh, H. Akazawa, T. Oka, E. Takimoto, D. Hayashi, T. Hosoda, M. Kawabata, K. Miyazono, et al.
Smads, Tak1, and Their Common Target Atf-2 Play a Critical Role in Cardiomyocyte Differentiation
J. Cell Biol., May 14, 2001; 153(4): 687 - 698.
[Abstract] [Full Text] [PDF]


Home page
JBJSHome page
A. H. Reddi
Bone Morphogenetic Proteins: From Basic Science to Clinical Applications
J. Bone Joint Surg. Am., April 1, 2001; 83(90010): S1 - 6.
[Full Text] [PDF]


Home page
JBJSHome page
A. H. Reddi
Bone Morphogenetic Proteins: From Basic Science to Clinical Applications
J. Bone Joint Surg. Am., March 1, 2001; 83(1_suppl_1): S1 - S6.
[Full Text] [PDF]


Home page
DevelopmentHome page
K. Mintzer, M. Lee, G Runke, J Trout, M Whitman, and M. Mullins
Lost-a-fin encodes a type I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation
Development, January 3, 2001; 128(6): 859 - 869.
[Abstract] [PDF]


Home page
EndocrinologyHome page
F. De Luca, K. M. Barnes, J. A. Uyeda, S. De-Levi, V. Abad, T. Palese, V. Mericq, and J. Baron
Regulation of Growth Plate Chondrogenesis by Bone Morphogenetic Protein-2
Endocrinology, January 1, 2001; 142(1): 430 - 436.
[Abstract] [Full Text] [PDF]


Home page
Biol. Reprod.Home page
Y. Ying and G.-Q. Zhao
Detection of Multiple Bone Morphogenetic Protein Messenger Ribonucleic Acids and Their Signal Transducer, Smad1, During Mouse Decidualization
Biol Reprod, December 1, 2000; 63(6): 1781 - 1786.
[Abstract] [Full Text]




© The Company of Biologists Ltd 1996