|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 122, Issue 11 3537-3547, Copyright © 1996 by Company of Biologists
JOURNAL ARTICLES |
JA Kreidberg, MJ Donovan, SL Goldstein, H Rennke, K Shepherd, RC Jones and R Jaenisch
Division of Nephrology, Children's Hospital, Boston, MA 02115, USA. Kreidberg@a1.tch.harvard.edu
A mutation was targeted to the murine alpha3 integrin gene. Homozygous mutant mice survived to birth, but died during the neonatal period. The mutation caused abnormal kidney and lung development. Mutant kidneys displayed decreased branching of the medullary collecting ducts, although the number of nephrons was not altered. Proximal tubules exhibited two distinct subsets of abnormalities, with the epithelial cells either containing excess lysosomes or becoming microcystic. In addition, glomerular development was markedly affected. In mutant kidneys, the extent of branching of glomerular capillary loops was decreased, with capillary lumina being wider than normal. The glomerular basement membrane was disorganized and glomerular podocytes were unable to form mature foot processes. Branching of the bronchi in lungs of mutant mice was also decreased and the large bronchi extended to the periphery. These results indicate a role for integrin receptors in basement membrane organization and branching morphogenesis.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  S. Trivedi, M. Zeier, and J. Reiser Role of podocytes in lupus nephritis Nephrol. Dial. Transplant., December 1, 2009; 24(12): 3607 - 3612. [Full Text] [PDF]
|
|
|
|
 |
|
 K. J. Reidy, G. Villegas, J. Teichman, D. Veron, W. Shen, J. Jimenez, D. Thomas, and A. Tufro Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development Development, December 1, 2009; 136(23): 3979 - 3989. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Zhang, G. Mernaugh, D.-H. Yang, L. Gewin, M. B. Srichai, R. C. Harris, J. M. Iturregui, R. D. Nelson, D. E. Kohan, D. Abrahamson, et al. {beta}1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity Development, October 1, 2009; 136(19): 3357 - 3366. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Dessapt, M. O. Baradez, A. Hayward, A. Dei Cas, S. M. Thomas, G. Viberti, and L. Gnudi Mechanical forces and TGF{beta}1 reduce podocyte adhesion through {alpha}3{beta}1 integrin downregulation Nephrol. Dial. Transplant., September 1, 2009; 24(9): 2645 - 2655. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Takabatake, T. Sugiyama, H. Kohara, T. Matsusaka, H. Kurihara, P. A. Koni, Y. Nagasawa, T. Hamano, I. Matsui, N. Kawada, et al. The CXCL12 (SDF-1)/CXCR4 Axis Is Essential for the Development of Renal Vasculature J. Am. Soc. Nephrol., August 1, 2009; 20(8): 1714 - 1723. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. V. Volpe, E. Chung, J. P. Ulm, B. F. Gilchrist, S. Ralston, K. T. Wang, and H. C. Nielsen Aberrant cell adhesion molecule expression in human bronchopulmonary sequestration and congenital cystic adenomatoid malformation Am J Physiol Lung Cell Mol Physiol, July 1, 2009; 297(1): L143 - L152. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Fukasawa, S. Bornheimer, K. Kudlicka, and M. G. Farquhar Slit Diaphragms Contain Tight Junction Proteins J. Am. Soc. Nephrol., July 1, 2009; 20(7): 1491 - 1503. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Wu, S. Kitamura, D. M. Truong, T. Rieg, V. Vallon, H. Sakurai, K. T. Bush, D. R. Vera, R. S. Ross, and S. K. Nigam {beta}1-Integrin is required for kidney collecting duct morphogenesis and maintenance of renal function Am J Physiol Renal Physiol, July 1, 2009; 297(1): F210 - F217. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Mitchell, C. Szekeres, V. Milano, K. B. Svenson, M. Nilsen-Hamilton, J. A. Kreidberg, and C. M. DiPersio {alpha}3{beta}1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3 J. Cell Sci., June 1, 2009; 122(11): 1778 - 1787. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Liu, N. Chattopadhyay, S. Qin, C. Szekeres, T. Vasylyeva, Z. X. Mahoney, M. Taglienti, C. M. Bates, H. A. Chapman, J. H. Miner, et al. Coordinate integrin and c-Met signaling regulate Wnt gene expression during epithelial morphogenesis Development, March 1, 2009; 136(5): 843 - 853. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Kim, M. C. Kugler, Y. Wei, K. K. Kim, X. Li, A. N. Brumwell, and H. A. Chapman Integrin {alpha}3{beta}1-dependent {beta}-catenin phosphorylation links epithelial Smad signaling to cell contacts J. Cell Biol., January 26, 2009; 184(2): 309 - 322. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Margadant, K. Raymond, M. Kreft, N. Sachs, H. Janssen, and A. Sonnenberg Integrin {alpha}3{beta}1 inhibits directional migration and wound re-epithelialization in the skin J. Cell Sci., January 15, 2009; 122(2): 278 - 288. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Turgeon and S. Meloche Interpreting Neonatal Lethal Phenotypes in Mouse Mutants: Insights Into Gene Function and Human Diseases Physiol Rev, January 1, 2009; 89(1): 1 - 26. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Yu, T. J. Carroll, J. Rajagopal, A. Kobayashi, Q. Ren, and A. P. McMahon A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney Development, January 1, 2009; 136(1): 161 - 171. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. E. Pitera, P. J. Scambler, and A. S. Woolf Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli Hum. Mol. Genet., December 15, 2008; 17(24): 3953 - 3964. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Shi, L. Yu, C. Chiu, Y. Sun, J. Chen, G. Khitrov, M. Merkenschlager, L. B. Holzman, W. Zhang, P. Mundel, et al. Podocyte-Selective Deletion of Dicer Induces Proteinuria and Glomerulosclerosis J. Am. Soc. Nephrol., November 1, 2008; 19(11): 2159 - 2169. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Silva, G. D'Amico, K. M. Hodivala-Dilke, and L. E. Reynolds Integrins: The Keys to Unlocking Angiogenesis Arterioscler Thromb Vasc Biol, October 1, 2008; 28(10): 1703 - 1713. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. M. Baleato, P. L. Guthrie, M.-C. Gubler, L. K. Ashman, and S. Roselli Deletion of Cd151 Results in a Strain-Dependent Glomerular Disease Due to Severe Alterations of the Glomerular Basement Membrane Am. J. Pathol., October 1, 2008; 173(4): 927 - 937. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Lamar, K. M. Pumiglia, and C. M. DiPersio An Immortalization-Dependent Switch in Integrin Function Up-regulates MMP-9 to Enhance Tumor Cell Invasion Cancer Res., September 15, 2008; 68(18): 7371 - 7379. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Wallgard, E. Larsson, L. He, M. Hellstrom, A. Armulik, M. H. Nisancioglu, G. Genove, P. Lindahl, and C. Betsholtz Identification of a Core Set of 58 Gene Transcripts With Broad and Specific Expression in the Microvasculature Arterioscler Thromb Vasc Biol, August 1, 2008; 28(8): 1469 - 1476. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Kreidberg Integrins and Matrix in the Glomerulus: Old Mysteries and New Insights J. Am. Soc. Nephrol., April 1, 2008; 19(4): 650 - 651. [Full Text] [PDF]
|
|
|
|
|
|
P. Topham, J. Barratt, and J. Feehally A spoonful of sugar helps the proteinuria go down? Nephrol. Dial. Transplant., March 1, 2008; 23(3): 813 - 815. [Full Text] [PDF]
|
|
|
|
|
|
S. E. Quaggin and J. A. Kreidberg Development of the renal glomerulus: good neighbors and good fences Development, February 15, 2008; 135(4): 609 - 620. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Rahuel, A. Filipe, L. Ritie, W. El Nemer, N. Patey-Mariaud, D. Eladari, J.-P. Cartron, P. Simon-Assmann, C. Le Van Kim, and Y. Colin Genetic inactivation of the laminin {alpha}5 chain receptor Lu/BCAM leads to kidney and intestinal abnormalities in the mouse Am J Physiol Renal Physiol, February 1, 2008; 294(2): F393 - F406. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Lei, D. Liu, Y. Huang, I. Jovin, S.-Y. Shai, T. Kyriakides, R. S. Ross, and F. J. Giordano Endothelial Expression of 1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling Mol. Cell. Biol., January 15, 2008; 28(2): 794 - 802. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. R. Vaughan and S. E. Quaggin How Do Mesangial and Endothelial Cells Form the Glomerular Tuft? J. Am. Soc. Nephrol., January 1, 2008; 19(1): 24 - 33. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Belvindrah, D. Graus-Porta, S. Goebbels, K.-A. Nave, and U. Muller 1 Integrins in Radial Glia But Not in Migrating Neurons Are Essential for the Formation of Cell Layers in the Cerebral Cortex J. Neurosci., December 12, 2007; 27(50): 13854 - 13865. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Liu, B. He, W. M. Liu, D. Zhou, J. V. Cox, and X. A. Zhang Tetraspanin CD151 Promotes Cell Migration by Regulating Integrin Trafficking J. Biol. Chem., October 26, 2007; 282(43): 31631 - 31642. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. R. Abrahamson, K. Isom, E. Roach, L. Stroganova, A. Zelenchuk, J. H. Miner, and P. L. St. John Laminin Compensation in Collagen {alpha}3(IV) Knockout (Alport) Glomeruli Contributes to Permeability Defects J. Am. Soc. Nephrol., September 1, 2007; 18(9): 2465 - 2472. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. S. Boosani, A. P. Mannam, D. Cosgrove, R. Silva, K. M. Hodivala-Dilke, V. G. Keshamouni, and A. Sudhakar Regulation of COX-2 mediated signaling by {alpha}3 type IV noncollagenous domain in tumor angiogenesis Blood, August 15, 2007; 110(4): 1168 - 1177. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Ren, Y. P. Yu, G. C. Tseng, C. Wu, K. Chen, U. N. Rao, J. Nelson, G. K. Michalopoulos, and J.-H. Luo Analysis of Integrin {alpha}7 Mutations in Prostate Cancer, Liver Cancer, Glioblastoma Multiforme, and Leiomyosarcoma J Natl Cancer Inst, June 6, 2007; 99(11): 868 - 880. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Wilkinson, T. Gilbert, G. Kinna, L.-A. Ruta, D. Pennisi, M. Kett, and M. H. Little Crim1KST264/KST264 Mice Implicate Crim1 in the Regulation of Vascular Endothelial Growth Factor-A Activity during Glomerular Vascular Development J. Am. Soc. Nephrol., June 1, 2007; 18(6): 1697 - 1708. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Takeda, A. R. Kazarov, C. E. Butterfield, B. D. Hopkins, L. E. Benjamin, A. Kaipainen, and M. E. Hemler Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro Blood, February 15, 2007; 109(4): 1524 - 1532. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. V. Dandapani, H. Sugimoto, B. D. Matthews, R. J. Kolb, S. Sinha, R. E. Gerszten, J. Zhou, D. E. Ingber, R. Kalluri, and M. R. Pollak {alpha}-Actinin-4 Is Required for Normal Podocyte Adhesion J. Biol. Chem., January 5, 2007; 282(1): 467 - 477. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Zhao, S. Itoh, X. Wang, T. Isaji, E. Miyoshi, Y. Kariya, K. Miyazaki, N. Kawasaki, N. Taniguchi, and J. Gu Deletion of Core Fucosylation on {alpha}3beta1 Integrin Down-regulates Its Functions J. Biol. Chem., December 15, 2006; 281(50): 38343 - 38350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Rippe, A. Rippe, A. Larsson, D. Asgeirsson, and B. Rippe Nature of glomerular capillary permeability changes following acute renal ischemia-reperfusion injury in rats Am J Physiol Renal Physiol, December 1, 2006; 291(6): F1362 - F1368. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Sachs, M. Kreft, M. A. van den Bergh Weerman, A. J. Beynon, T. A. Peters, J. J. Weening, and A. Sonnenberg Kidney failure in mice lacking the tetraspanin CD151 J. Cell Biol., October 9, 2006; 175(1): 33 - 39. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. J. del Zoppo and R. Milner Integrin-Matrix Interactions in the Cerebral Microvasculature Arterioscler Thromb Vasc Biol, September 1, 2006; 26(9): 1966 - 1975. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Dai, D. B. Stolz, S. I. Bastacky, R. St.-Arnaud, C. Wu, S. Dedhar, and Y. Liu Essential Role of Integrin-Linked Kinase in Podocyte Biology: Bridging the Integrin and Slit Diaphragm Signaling J. Am. Soc. Nephrol., August 1, 2006; 17(8): 2164 - 2175. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. K. Behera, E. Hildebrand, S. Uematsu, S. Akira, J. Coburn, and L. T. Hu Identification of a TLR-Independent Pathway for Borrelia burgdorferi-Induced Expression of Matrix Metalloproteinases and Inflammatory Mediators through Binding to Integrin {alpha}3beta1 J. Immunol., July 1, 2006; 177(1): 657 - 664. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. E. Winterwood, A. Varzavand, M. N. Meland, L. K. Ashman, and C. S. Stipp A Critical Role for Tetraspanin CD151 in {alpha}3beta1 and {alpha}6beta4 Integrin-dependent Tumor Cell Functions on Laminin-5 Mol. Biol. Cell, June 1, 2006; 17(6): 2707 - 2721. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. V. Cardoso and J. Lu Regulation of early lung morphogenesis: questions, facts and controversies Development, May 1, 2006; 133(9): 1611 - 1624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Bajanca, M. Luz, K. Raymond, G. G. Martins, A. Sonnenberg, S. Tajbakhsh, M. Buckingham, and S. Thorsteinsdottir Integrin {alpha}6{beta}1-laminin interactions regulate early myotome formation in the mouse embryo Development, May 1, 2006; 133(9): 1635 - 1644. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Sanchez-Esteban, Y. Wang, E. J. Filardo, L. P. Rubin, and D. E. Ingber Integrins {beta}1, {alpha}6, and {alpha}3 contribute to mechanical strain-induced differentiation of fetal lung type II epithelial cells via distinct mechanisms Am J Physiol Lung Cell Mol Physiol, February 1, 2006; 290(2): L343 - L350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. F. Bek, M. Bayer, B. Muller, S. Greiber, D. Lang, A. Schwab, C. August, E. Springer, R. Rohrbach, T. B. Huber, et al. Expression and Function of C/EBP Homology Protein (GADD153) in Podocytes Am. J. Pathol., January 1, 2006; 168(1): 20 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. H.L. Hamelers, C. Olivo, A. E.E. Mertens, D. M. Pegtel, R. A. van der Kammen, A. Sonnenberg, and J. G. Collard The Rac activator Tiam1 is required for {alpha}3{beta}1-mediated laminin-5 deposition, cell spreading, and cell migration J. Cell Biol., December 5, 2005; 171(5): 871 - 881. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Martin, D. M. Roth, D. A. Jans, C. W. Pouton, L. J. Partridge, P. N. Monk, and G. W. Moseley Tetraspanins in Viral Infections: a Fundamental Role in Viral Biology? J. Virol., September 1, 2005; 79(17): 10839 - 10851. [Full Text] [PDF]
|
|
|
|
 |
|
 S. Lehtonen, J. J. Ryan, K. Kudlicka, N. Iino, H. Zhou, and M. G. Farquhar Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and {alpha}-actinin are components of the nephrin multiprotein complex PNAS, July 12, 2005; 102(28): 9814 - 9819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. L. Hunt, M. R. Pollak, and B. M. Denker Cultured Podocytes Establish a Size-Selective Barrier Regulated by Specific Signaling Pathways and Demonstrate Synchronized Barrier Assembly in a Calcium Switch Model of Junction Formation J. Am. Soc. Nephrol., June 1, 2005; 16(6): 1593 - 1602. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Iyer, K. Pumiglia, and C. M. DiPersio {alpha}3{beta}1 integrin regulates MMP-9 mRNA stability in immortalized keratinocytes: a novel mechanism of integrin-mediated MMP gene expression J. Cell Sci., March 15, 2005; 118(6): 1185 - 1195. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Nishiuchi, N. Sanzen, S. Nada, Y. Sumida, Y. Wada, M. Okada, J. Takagi, H. Hasegawa, and K. Sekiguchi Potentiation of the ligand-binding activity of integrin {alpha}3{beta}1 via association with tetraspanin CD151 PNAS, February 8, 2005; 102(6): 1939 - 1944. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Yang, O. V. Kovalenko, W. Tang, C. Claas, C. S. Stipp, and M. E. Hemler Palmitoylation supports assembly and function of integrin-tetraspanin complexes J. Cell Biol., December 20, 2004; 167(6): 1231 - 1240. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. S. Schmid, S. Shelton, A. Stanco, Y. Yokota, J. A. Kreidberg, and E. S. Anton {alpha}3{beta}1 integrin modulates neuronal migration and placement during early stages of cerebral cortical development Development, December 15, 2004; 131(24): 6023 - 6031. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S.-i. Kurata, T. Okuyama, M. Osada, T. Watanabe, Y. Tomimori, S. Sato, A. Iwai, T. Tsuji, Y. Ikawa, and I. Katoh p51/p63 Controls Subunit {alpha}3 of the Major Epidermis Integrin Anchoring the Stem Cells to the Niche J. Biol. Chem., November 26, 2004; 279(48): 50069 - 50077. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Karamatic Crew, N. Burton, A. Kagan, C. A. Green, C. Levene, F. Flinter, R. L. Brady, G. Daniels, and D. J. Anstee CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin Blood, October 15, 2004; 104(8): 2217 - 2223. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Chen, R. Roberts, M. Pohl, S. Nigam, J. Kreidberg, Z. Wang, J. Heino, J. Ivaska, S. Coffa, R. C. Harris, et al. Differential expression of collagen- and laminin-binding integrins mediates ureteric bud and inner medullary collecting duct cell tubulogenesis Am J Physiol Renal Physiol, October 1, 2004; 287(4): F602 - F611. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Reiser and P. Mundel Danger Signaling by Glomerular Podocytes Defines a Novel Function of Inducible B7-1 in the Pathogenesis of Nephrotic Syndrome J. Am. Soc. Nephrol., September 1, 2004; 15(9): 2246 - 2248. [Full Text] [PDF]
|
|
|
|
|
|
J. Reiser, J. Oh, I. Shirato, K. Asanuma, A. Hug, T. M. Mundel, K. Honey, K. Ishidoh, E. Kominami, J. A. Kreidberg, et al. Podocyte Migration during Nephrotic Syndrome Requires a Coordinated Interplay between Cathepsin L and {alpha}3 Integrin J. Biol. Chem., August 13, 2004; 279(33): 34827 - 34832. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. K.Y. Siu and C. Y. Cheng Extracellular Matrix: Recent Advances on Its Role in Junction Dynamics in the Seminiferous Epithelium During Spermatogenesis Biol Reprod, August 1, 2004; 71(2): 375 - 391. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. D. Wright, S. M. Geary, S. Fitter, G. W. Moseley, L.-M. Lau, K.-C. Sheng, V. Apostolopoulos, E. G. Stanley, D. E. Jackson, and L. K. Ashman Characterization of Mice Lacking the Tetraspanin Superfamily Member CD151 Mol. Cell. Biol., July 1, 2004; 24(13): 5978 - 5988. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. K. Dey, H. Lim, S. K. Das, J. Reese, B. C. Paria, T. Daikoku, and H. Wang Molecular Cues to Implantation Endocr. Rev., June 1, 2004; 25(3): 341 - 373. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Pal-Ghosh, A. Pajoohesh-Ganji, M. Brown, and M. A. Stepp A Mouse Model for the Study of Recurrent Corneal Epithelial Erosions: {alpha}9{beta}1 Integrin Implicated in Progression of the Disease Invest. Ophthalmol. Vis. Sci., June 1, 2004; 45(6): 1775 - 1788. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Benzing Signaling at the Slit Diaphragm J. Am. Soc. Nephrol., June 1, 2004; 15(6): 1382 - 1391. [Full Text] [PDF]
|
|
|
|
|
|
Y. Chen, D. Lasaitiene, B. G. Gabrielsson, L. M.S. Carlsson, H. Billig, B. Carlsson, N. Marcussen, X.-F. Sun, and P. Friberg Neonatal Losartan Treatment Suppresses Renal Expression of Molecules Involved in Cell-Cell and Cell-Matrix Interactions J. Am. Soc. Nephrol., May 1, 2004; 15(5): 1232 - 1243. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. S. Kanwar, J. Wada, S. Lin, F. R. Danesh, S. S. Chugh, Q. Yang, T. Banerjee, and J. W. Lomasney Update of extracellular matrix, its receptors, and cell adhesion molecules in mammalian nephrogenesis Am J Physiol Renal Physiol, February 1, 2004; 286(2): F202 - F215. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. D. Wilson Polycystic Kidney Disease N. Engl. J. Med., January 8, 2004; 350(2): 151 - 164. [Full Text] [PDF]
|
|
|
|
|
|
C. S. Stipp, T. V. Kolesnikova, and M. E. Hemler EWI-2 regulates {alpha}3{beta}1 integrin-dependent cell functions on laminin-5 J. Cell Biol., December 8, 2003; 163(5): 1167 - 1177. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. S. Haas, K. Amann, J. Schittny, B. Blaser, U. Muller, and A. Hartner Glomerular and Renal Vascular Structural Changes in {alpha}8 Integrin-Deficient Mice J. Am. Soc. Nephrol., September 1, 2003; 14(9): 2288 - 2296. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. M. Cowan, N. Quarto, S. M. Warren, A. Salim, and M. T. Longaker Age-related Changes in the Biomolecular Mechanisms of Clvarial Osteoblast Biology Affect Fibroblast Growth Factor-2 Signaling and Osteogenesis J. Biol. Chem., August 22, 2003; 278(34): 32005 - 32013. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C.-S. Chan, E. J. Weeber, S. Kurup, J. D. Sweatt, and R. L. Davis Integrin Requirement for Hippocampal Synaptic Plasticity and Spatial Memory J. Neurosci., August 6, 2003; 23(18): 7107 - 7116. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. SHEPPARD Functions of Pulmonary Epithelial Integrins: From Development to Disease Physiol Rev, July 1, 2003; 83(3): 673 - 686. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. J. A. Conti, R. J. Rudling, A. Robson, and K. M. Hodivala-Dilke {alpha}3{beta}1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis J. Cell Sci., July 1, 2003; 116(13): 2737 - 2747. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. H. Grayson, R. S. Hotchkiss, I. E. Karl, M. J. Holtzman, and D. D. Chaplin Intravital microscopy comparing T lymphocyte trafficking to the spleen and the mesenteric lymph node Am J Physiol Heart Circ Physiol, June 1, 2003; 284(6): H2213 - H2226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Kikkawa, I. Virtanen, and J. H. Miner Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin {alpha}5 in the glomerular basement membrane J. Cell Biol., April 14, 2003; 161(1): 187 - 196. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. S. Schmid and E.S. Anton Role of Integrins in the Development of the Cerebral Cortex Cereb Cortex, March 1, 2003; 13(3): 219 - 224. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Kreidberg Podocyte Differentiation and Glomerulogenesis J. Am. Soc. Nephrol., March 1, 2003; 14(3): 806 - 814. [Full Text] [PDF]
|
|
|
|
|
|
H. Pavenstadt, W. Kriz, and M. Kretzler Cell Biology of the Glomerular Podocyte Physiol Rev, January 1, 2003; 83(1): 253 - 307. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Muschler, D. Levy, R. Boudreau, M. Henry, K. Campbell, and M. J. Bissell A Role for Dystroglycan in Epithelial Polarization: Loss of Function in Breast Tumor Cells Cancer Res., December 1, 2002; 62(23): 7102 - 7109. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Mundel and S. J. Shankland Podocyte Biology and Response to Injury J. Am. Soc. Nephrol., December 1, 2002; 13(12): 3005 - 3015. [Full Text] [PDF]
|
|
|
|
|
|
K. Schumacher, R. Strehl, U. de Vries, H. J. Groene, and W. W. Minuth SBA-Positive Fibers between the CD Ampulla, Mesenchyme, and Renal Capsule J. Am. Soc. Nephrol., October 1, 2002; 13(10): 2446 - 2453. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. R. Kazarov, X. Yang, C. S. Stipp, B. Sehgal, and M. E. Hemler An extracellular site on tetraspanin CD151 determines {alpha}3 and {alpha}6 integrin-dependent cellular morphology J. Cell Biol., September 29, 2002; 158(7): 1299 - 1309. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Hamano, J. A. Grunkemeyer, A. Sudhakar, M. Zeisberg, D. Cosgrove, R. Morello, B. Lee, H. Sugimoto, and R. Kalluri Determinants of Vascular Permeability in the Kidney Glomerulus J. Biol. Chem., August 16, 2002; 277(34): 31154 - 31162. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. A. Natoli, J. Liu, V. Eremina, K. Hodgens, C. Li, Y. Hamano, P. Mundel, R. Kalluri, J. H. Miner, S. E. Quaggin, et al. A Mutant Form of the Wilms' Tumor Suppressor Gene WT1 Observed in Denys-Drash Syndrome Interferes with Glomerular Capillary Development J. Am. Soc. Nephrol., August 1, 2002; 13(8): 2058 - 2067. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. M. Mercurio Lessons from the {alpha}2 Integrin Knockout Mouse Am. J. Pathol., July 1, 2002; 161(1): 3 - 6. [Full Text] [PDF]
|
|
|
|
|
|
J. Reiser, G. von Gersdorff, M. Simons, K. Schwarz, C. Faul, L. Giardino, T. Heider, M. Loos, and P. Mundel Novel concepts in understanding and management of glomerular proteinuria Nephrol. Dial. Transplant., June 1, 2002; 17(6): 951 - 955. [Full Text] [PDF]
|
|
|
|
|
|
M. A. Saleem, M. J. O'Hare, J. Reiser, R. J. Coward, C. D. Inward, T. Farren, C. Y. Xing, L. Ni, P. W. Mathieson, and P. Mundel A Conditionally Immortalized Human Podocyte Cell Line Demonstrating Nephrin and Podocin Expression J. Am. Soc. Nephrol., March 1, 2002; 13(3): 630 - 638. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Hartner, N. Cordasic, B. Klanke, U. Muller, R. B. Sterzel, and K. F. Hilgers The {alpha}8 Integrin Chain Affords Mechanical Stability to the Glomerular Capillary Tuft in Hypertensive Glomerular Disease Am. J. Pathol., March 1, 2002; 160(3): 861 - 867. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. E. Fisher, L. Michael, M. W. Barnett, and J. A. Davies Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney Development, November 1, 2001; 128(21): 4329 - 4338. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Kostka, R. Giltay, W. Bloch, K. Addicks, R. Timpl, R. Fassler, and M.-L. Chu Perinatal Lethality and Endothelial Cell Abnormalities in Several Vessel Compartments of Fibulin-1-Deficient Mice Mol. Cell. Biol., October 15, 2001; 21(20): 7025 - 7034. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Bouvard, C. Brakebusch, E. Gustafsson, A. Aszodi, T. Bengtsson, A. Berna, and R. Fassler Functional Consequences of Integrin Gene Mutations in Mice Circ. Res., July 30, 2001; 89(3): 211 - 223. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. H. Miner Mystery solved: discovery of a novel integrin ligand in the developing kidney J. Cell Biol., July 23, 2001; 154(2): 257 - 260. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Doyonnas, D. B. Kershaw, C. Duhme, H. Merkens, S. Chelliah, T. Graf, and K. M. McNagny Anuria, Omphalocele, and Perinatal Lethality in Mice Lacking the Cd34-Related Protein Podocalyxin J. Exp. Med., July 2, 2001; 194(1): 13 - 28. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. L. BULLOCK, T. M. JOHNSON, Q. BAO, R. C. HUGHES, P. J. D. WINYARD, and A. S. WOOLF Galectin-3 Modulates Ureteric Bud Branching in Organ Culture of the Developing Mouse Kidney J. Am. Soc. Nephrol., March 1, 2001; 12(3): 515 - 523. [Abstract] [Full Text]
|
|
