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Development, Vol 122, Issue 12 3765-3773, Copyright © 1996 by Company of Biologists

JOURNAL ARTICLES

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway

C Shawber, D Nofziger, JJ Hsieh, C Lindsell, O Bogler, D Hayward and G Weinmaster
Department of Biological Chemistry, UCLA School of Medicine, Los Angeles, CA 90095-1737, USA.

Notch controls cell fate by inhibiting cellular differentiation, presumably through activation of the transcriptional regulator human C promoter Binding Factor (CBF1), which transactivates the hairy and Enhancer of split (HES-1) gene. However, we describe constitutively active forms of Notch1, which inhibit muscle cell differentiation but do not interact with CBF1 or upregulate endogenous HES-1 expression. In addition, Jagged-Notch interactions that prevent the expression of muscle cell specific genes do not involve the upregulation of endogenous HES-1. In fact, exogenous expression of HES-1 in C2C12 myoblasts does not block myogenesis. Our data demonstrate the existence of a CBF1-independent pathway by which Notch inhibits differentiation. We therefore propose that Notch signaling activates at least two different pathways: one which involves CBF1 as an intermediate and one which does not.


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Home page
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[Abstract] [Full Text] [PDF]

Home page
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Mol. Cell. Biol., November 1, 2002; 22(21): 7688 - 7700.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
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J. Immunol., October 15, 2002; 169(8): 4273 - 4278.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
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J. Biol. Chem., August 9, 2002; 277(33): 29760 - 29764.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
S. Jeffries, D. J. Robbins, and A. J. Capobianco
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Mol. Cell. Biol., June 1, 2002; 22(11): 3927 - 3941.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
V. Sriuranpong, M. W. Borges, C. L. Strock, E. K. Nakakura, D. N. Watkins, C. M. Blaumueller, B. D. Nelkin, and D. W. Ball
Notch Signaling Induces Rapid Degradation of Achaete-Scute Homolog 1
Mol. Cell. Biol., May 1, 2002; 22(9): 3129 - 3139.
[Abstract] [Full Text] [PDF]

Home page
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S. Hitoshi, T. Alexson, V. Tropepe, D. Donoviel, A. J. Elia, J. S. Nye, R. A. Conlon, T. W. Mak, A. Bernstein, and D. van der Kooy
Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells
Genes & Dev., April 1, 2002; 16(7): 846 - 858.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
J. Cossins, A. E. Vernon, Y. Zhang, A. Philpott, and P. H. Jones
Hes6 regulates myogenic differentiation
Development, January 5, 2002; 129(9): 2195 - 2207.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S.-i. Yamamoto, M. Nagao, M. Sugimori, H. Kosako, H. Nakatomi, N. Yamamoto, H. Takebayashi, Y.-i. Nabeshima, T. Kitamura, G. Weinmaster, et al.
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J. Neurosci., December 15, 2001; 21(24): 9814 - 9823.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
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p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1
Mol. Cell. Biol., November 15, 2001; 21(22): 7761 - 7774.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
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[Abstract] [Full Text] [PDF]

Home page
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Stem Cells, November 1, 2001; 19(6): 543 - 552.
[Abstract] [Full Text]

Home page
 J. Exp. Med.Home page
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Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation
J. Exp. Med., October 1, 2001; 194(7): 991 - 1002.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
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Mol. Cell. Biol., September 15, 2001; 21(18): 6222 - 6232.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
T. Iso, V. Sartorelli, G. Chung, T. Shichinohe, L. Kedes, and Y. Hamamori
HERP, a New Primary Target of Notch Regulated by Ligand Binding
Mol. Cell. Biol., September 1, 2001; 21(17): 6071 - 6079.
[Abstract] [Full Text] [PDF]

Home page
 J. Virol.Home page
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Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus
J. Virol., July 1, 2001; 75(13): 5899 - 5912.
[Abstract] [Full Text] [PDF]

Home page
 Cancer Res.Home page
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Notch Signaling Induces Cell Cycle Arrest in Small Cell Lung Cancer Cells
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Notch signalling acts in postmitotic avian myogenic cells to control MyoD activation
Development, January 1, 2001; 128(1): 107 - 116.
[Abstract] [PDF]

Home page
 Mol. Cell. Biol.Home page
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Mol. Cell. Biol., October 15, 2000; 20(20): 7505 - 7515.
[Abstract] [Full Text]

Home page
 J. Immunol.Home page
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[Abstract] [Full Text] [PDF]

Home page
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 Mol. Cell. Biol.Home page
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Mol. Cell. Biol., June 1, 2000; 20(11): 3831 - 3842.
[Abstract] [Full Text]

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[Abstract] [Full Text]

Home page
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[Abstract] [Full Text]

Home page
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