|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 124, Issue 17 3449-3460, Copyright © 1997 by Company of Biologists
JOURNAL ARTICLES |
Y Wakamatsu and JA Weston
Institute of Neuroscience, University of Oregon, Eugene 97403-1254, USA.
We have identified three avian (chicken) Hu/elav family RNA-binding protein genes. cHuD and cHuC are expressed specifically in neurons of both the central and peripheral nervous systems. Although cHuA is expressed in a wide variety of tissues, including neurogenic precursor cells, it is transiently down-regulated, and is then re-expressed in maturing neurons. Misexpression of cHuD in cultured neural crest cells results in a dramatic increase in the proportion of cells exhibiting neuronal morphology, molecular markers for neurons, and neurotrophin dependence. These data confirm that cHuD protein is involved in regulating neuronal differentiation.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  C. Galichet, F. Guillemot, and C. M. Parras Neurogenin 2 has an essential role in development of the dentate gyrus Development, June 1, 2008; 135(11): 2031 - 2041. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. McCabe and M. Bronner-Fraser Essential role for PDGF signaling in ophthalmic trigeminal placode induction Development, May 15, 2008; 135(10): 1863 - 1874. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q. Schwarz, J. M. Vieira, B. Howard, B. J. Eickholt, and C. Ruhrberg Neuropilin 1 and 2 control cranial gangliogenesis and axon guidance through neural crest cells Development, May 1, 2008; 135(9): 1605 - 1613. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Ratti, C. Fallini, C. Colombrita, A. Pascale, U. Laforenza, A. Quattrone, and V. Silani Post-transcriptional Regulation of Neuro-oncological Ventral Antigen 1 by the Neuronal RNA-binding Proteins ELAV J. Biol. Chem., March 21, 2008; 283(12): 7531 - 7541. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Zhu, M. N. Hinman, R. A. Hasman, P. Mehta, and H. Lou Regulation of Neuron-Specific Alternative Splicing of Neurofibromatosis Type 1 Pre-mRNA Mol. Cell. Biol., February 15, 2008; 28(4): 1240 - 1251. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Wakamatsu, N. Nakamura, J.-A. Lee, G. J. Cole, and N. Osumi Transitin, a nestin-like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells Development, July 1, 2007; 134(13): 2425 - 2433. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Zhu, R. A. Hasman, V. A. Barron, G. Luo, and H. Lou A Nuclear Function of Hu Proteins as Neuron-specific Alternative RNA Processing Regulators Mol. Biol. Cell, December 1, 2006; 17(12): 5105 - 5114. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Ratti, C. Fallini, L. Cova, R. Fantozzi, C. Calzarossa, E. Zennaro, A. Pascale, A. Quattrone, and V. Silani A role for the ELAV RNA-binding proteins in neural stem cells: stabilization of Msi1 mRNA. J. Cell Sci., April 1, 2006; 119(Pt 7): 1442 - 1452. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Sakai, T. Suzuki, N. Osumi, and Y. Wakamatsu Cooperative action of Sox9, Snail2 and PKA signaling in early neural crest development Development, April 1, 2006; 133(7): 1323 - 1333. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. D. Borgeson and M.-L. Samson Shared RNA-binding sites for interacting members of the Drosophila ELAV family of neuronal proteins Nucleic Acids Res., November 10, 2005; 33(19): 6372 - 6383. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Canete-Soler, K. S. Reddy, D. R. Tolan, and J. Zhai Aldolases A and C Are Ribonucleolytic Components of a Neuronal Complex That Regulates the Stability of the Light-Neurofilament mRNA J. Neurosci., April 27, 2005; 25(17): 4353 - 4364. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Akamatsu, H. Fujihara, T. Mitsuhashi, M. Yano, S. Shibata, Y. Hayakawa, H. J. Okano, S.-i. Sakakibara, H. Takano, T. Takano, et al. The RNA-binding protein HuD regulates neuronal cell identity and maturation PNAS, March 22, 2005; 102(12): 4625 - 4630. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Pascale, P. A. Gusev, M. Amadio, T. Dottorini, S. Govoni, D. L. Alkon, and A. Quattrone Increase of the RNA-binding protein HuD and posttranscriptional up-regulation of the GAP-43 gene during spatial memory PNAS, February 3, 2004; 101(5): 1217 - 1222. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. van der Giessen, S. Di-Marco, E. Clair, and I. E. Gallouzi RNAi-mediated HuR Depletion Leads to the Inhibition of Muscle Cell Differentiation J. Biol. Chem., November 21, 2003; 278(47): 47119 - 47128. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Lee, E. L. Shen, A. Fiser, A. Sali, and S. Guo The zebrafish forkhead transcription factor Foxi1 specifies epibranchial placode-derived sensory neurons Development, June 15, 2003; 130(12): 2669 - 2679. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Endo, N. Osumi, and Y. Wakamatsu Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development Development, March 4, 2003; 129(4): 863 - 873. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Sugiyama and H. Nakamura The role of Grg4 in tectal laminar formation Development, February 1, 2003; 130(3): 451 - 462. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Kasashima, E. Sakashita, K. Saito, and H. Sakamoto Complex formation of the neuron-specific ELAV-like Hu RNA-binding proteins Nucleic Acids Res., October 15, 2002; 30(20): 4519 - 4526. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Nie, J. Wu, J. Zhai, H. Lin, W. Ge, W. W. Schlaepfer, and R. Canete-Soler Untranslated Element in Neurofilament mRNA Has Neuropathic Effect on Motor Neurons of Transgenic Mice J. Neurosci., September 1, 2002; 22(17): 7662 - 7670. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. C. Beckel-Mitchener, A. Miera, R. Keller, and N. I. Perrone-Bizzozero Poly(A) Tail Length-dependent Stabilization of GAP-43 mRNA by the RNA-binding Protein HuD J. Biol. Chem., July 26, 2002; 277(31): 27996 - 28002. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Cuadrado, C. Navarro-Yubero, H. Furneaux, J. Kinter, P. Sonderegger, and A. Munoz HuD binds to three AU-rich sequences in the 3'-UTR of neuroserpin mRNA and promotes the accumulation of neuroserpin mRNA and protein Nucleic Acids Res., May 15, 2002; 30(10): 2202 - 2211. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. A. Burgess and O. Reiner Alternative Splice Variants of Doublecortin-like Kinase Are Differentially Expressed and Have Different Kinase Activities J. Biol. Chem., May 10, 2002; 277(20): 17696 - 17705. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Toba, J. Qui, S. P. Koushika, and K. White Ectopic expression of Drosophila ELAV and human HuD in Drosophila wing disc cells reveals functional distinctions and similarities J. Cell Sci., January 6, 2002; 115(11): 2413 - 2421. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. D. Keene Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome PNAS, June 19, 2001; 98(13): 7018 - 7024. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Imai, A. Tokunaga, T. Yoshida, M. Hashimoto, K. Mikoshiba, G. Weinmaster, M. Nakafuku, and H. Okano The Neural RNA-Binding Protein Musashi1 Translationally Regulates Mammalian numb Gene Expression by Interacting with Its mRNA Mol. Cell. Biol., June 15, 2001; 21(12): 3888 - 3900. [Abstract] [Full Text]
|
|
|
|
 |
|
 L. B. Nabors, G. Y. Gillespie, L. Harkins, and P. H. King HuR, a RNA Stability Factor, Is Expressed in Malignant Brain Tumors and Binds to Adenine- and Uridine-rich Elements within the 3' Untranslated Regions of Cytokine and Angiogenic Factor mRNAs Cancer Res., March 1, 2001; 61(5): 2154 - 2161. [Abstract] [Full Text]
|
|
|
|
|
|
S. A. Tenenbaum, C. C. Carson, P. J. Lager, and J. D. Keene Identifying mRNA subsets in messenger ribonucleoprotein complexes by using cDNA arrays PNAS, December 19, 2000; 97(26): 14085 - 14090. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. D. Mobarak, K. D. Anderson, M. Morin, A. Beckel-Mitchener, S. L. Rogers, H. Furneaux, P. King, and N. I. Perrone-Bizzozero The RNA-binding Protein HuD Is Required for GAP-43 mRNA Stability, GAP-43 Gene Expression, and PKC-dependent Neurite Outgrowth in PC12 Cells Mol. Biol. Cell, September 1, 2000; 11(9): 3191 - 3203. [Abstract] [Full Text]
|
|
|
|
|
|
M. Inoue, Y. Muto, H. Sakamoto, and S. Yokoyama NMR studies on functional structures of the AU-rich element-binding domains of Hu antigen C Nucleic Acids Res., April 15, 2000; 28(8): 1743 - 1750. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Maynard, Y Wakamatsu, and J. Weston Cell interactions within nascent neural crest cell populations transiently promote death of neurogenic precursors Development, January 11, 2000; 127(21): 4561 - 4572. [Abstract] [PDF]
|
|
|
|
|
|
Y Wakamatsu, T. Maynard, and J. Weston Fate determination of neural crest cells by NOTCH-mediated lateral inhibition and asymmetrical cell division during gangliogenesis Development, January 7, 2000; 127(13): 2811 - 2821. [Abstract] [PDF]
|
|
|
|
|
|
Y Watanabe and H Nakamura Control of chick tectum territory along dorsoventral axis by Sonic hedgehog Development, January 3, 2000; 127(5): 1131 - 1140. [Abstract] [PDF]
|
|
|
|
|
|
M. Farah, J. Olson, H. Sucic, R. Hume, S. Tapscott, and D. Turner Generation of neurons by transient expression of neural bHLH proteins in mammalian cells Development, January 2, 2000; 127(4): 693 - 702. [Abstract] [PDF]
|
|
|
|
|
|
Y. Nakamura, S.-i. Sakakibara, T. Miyata, M. Ogawa, T. Shimazaki, S. Weiss, R. Kageyama, and H. Okano The bHLH Gene Hes1 as a Repressor of the Neuronal Commitment of CNS Stem Cells J. Neurosci., January 1, 2000; 20(1): 283 - 293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Akamatsu, H. J. Okano, N. Osumi, T. Inoue, S. Nakamura, S.-I. Sakakibara, M. Miura, N. Matsuo, R. B. Darnell, and H. Okano Mammalian ELAV-like neuronal RNA-binding proteins HuB and HuC promote neuronal development in both the central and the peripheral nervous systems PNAS, August 17, 1999; 96(17): 9885 - 9890. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. E. Aranda-Abreu, L. Behar, S. Chung, H. Furneaux, and I. Ginzburg Embryonic Lethal Abnormal Vision-Like RNA-Binding Proteins Regulate Neurite Outgrowth and Tau Expression in PC12 Cells J. Neurosci., August 15, 1999; 19(16): 6907 - 6917. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Canete-Soler, D. G. Silberg, M. D. Gershon, and W. W. Schlaepfer Mutation in Neurofilament Transgene Implicates RNA Processing in the Pathogenesis of Neurodegenerative Disease J. Neurosci., February 15, 1999; 19(4): 1273 - 1283. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Antic, N. Lu, and J. D. Keene ELAV tumor antigen, Hel-N1, increases translation of neurofilament M mRNA and induces formation of neurites in human teratocarcinoma cells Genes & Dev., February 15, 1999; 13(4): 449 - 461. [Abstract] [Full Text]
|
|
|
|
|
|
Y. Yannoni and K White Domain necessary for Drosophila ELAV nuclear localization: function requires nuclear ELAV J. Cell Sci., January 12, 1999; 112(24): 4501 - 4512. [Abstract] [PDF]
|
|
|
|
|
|
M Stanke, D Junghans, M Geissen, C Goridis, U Ernsberger, and H Rohrer The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons Development, January 9, 1999; 126(18): 4087 - 4094. [Abstract] [PDF]
|
|
|
|
|
|
J. D. Keene Why is Hu where? Shuttling of early-response-gene messenger RNA subsets PNAS, January 5, 1999; 96(1): 5 - 7. [Full Text] [PDF]
|
|
|
|
|
|
X. C. Fan and J. A. Steitz HNS, a nuclear-cytoplasmic shuttling sequence in HuR PNAS, December 22, 1998; 95(26): 15293 - 15298. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-L. Samson Evidence for 3' Untranslated Region-Dependent Autoregulation of the Drosophila Gene Encoding the Neuronal Nuclear RNA-Binding Protein ELAV Genetics, October 1, 1998; 150(2): 723 - 733. [Abstract] [Full Text]
|
|
|
|
|
|
B. Joseph, M. Orlian, and H. Furneaux p21waf1 mRNA Contains a Conserved Element in Its 3'-Untranslated Region That Is Bound by the Elav-like mRNA-stabilizing Proteins J. Biol. Chem., August 7, 1998; 273(32): 20511 - 20516. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
U Atasoy, J Watson, D Patel, and J. Keene ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation J. Cell Sci., January 11, 1998; 111(21): 3145 - 3156. [Abstract] [PDF]
|
|
|
|
|
|
Y Wakamatsu, M Mochii, K. Vogel, and J. Weston Avian neural crest-derived neurogenic precursors undergo apoptosis on the lateral migration pathway Development, January 11, 1998; 125(21): 4205 - 4213. [Abstract] [PDF]
|
|
|
|
|
|
K Fukuda, Y Tanigawa, G Fujii, S Yasugi, and S Hirohashi cFKBP/SMAP; a novel molecule involved in the regulation of smooth muscle differentiation Development, January 9, 1998; 125(18): 3535 - 3542. [Abstract] [PDF]
|
|
|
|
|
|
P. J. Good, Q. Chen, S. J. Warner, and D. C. Herring A Family of Human RNA-binding Proteins Related to the Drosophila Bruno Translational Regulator J. Biol. Chem., September 8, 2000; 275(37): 28583 - 28592. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Planque, L. Leconte, F. M. Coquelle, P. Martin, and S. Saule Specific Pax-6/Microphthalmia Transcription Factor Interactions Involve Their DNA-binding Domains and Inhibit Transcriptional Properties of Both Proteins J. Biol. Chem., July 27, 2001; 276(31): 29330 - 29337. [Abstract] [Full Text] [PDF]
|
|
