|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 125, Issue 10 1791-1801, Copyright © 1998 by Company of Biologists
JOURNAL ARTICLES |
V Knezevic, R De Santo and S Mackem
Laboratory of Pathology, NCI, NIH, Bethesda, MD 20892, USA.
Development of the posterior body (lumbosacral region and tail) in vertebrates is delayed relative to gastrulation. In amniotes, it proceeds with the replacement of the regressed node and primitive streak by a caudal blastema-like mass of mesenchyme known as the tail bud. Despite apparent morphological dissimilarities, recent results suggest that tail development in amniotes is in essence a continuation of gastrulation, as is the case in Xenopus. However, this has been inferred primarily from the outcome of fate mapping studies demonstrating discrete, regionalized cell populations in the tail bud, like those present at gastrulation. Our analysis of the tail bud distribution of several molecular markers that are expressed in specific spatial domains during chick gastrulation confirms these results. Furthermore, we present evidence that gastrulation-like ingression movements from the surface continue in the early chick tail bud and that the established tail bud retains organizer activity. This 'tail organizer' has the expected properties of being able to recruit uncommitted host cells into a new embryonic axis and induce host neural tissue with posteriorly regionalized gene expression when grafted to competent host cells that are otherwise destined to form only extra-embryonic tissue. Together, these results indicate that chick tail development is mechanistically continuous with gastrulation and that the developing tail in chick may serve as a useful experimental adjunct to investigate the molecular basis of inductive interactions operating during gastrulation, considering that residual tail organizing activity is still present at a surprisingly late stage.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  V. Wilson, I. Olivera-Martinez, and K. G. Storey Stem cells, signals and vertebrate body axis extension Development, May 15, 2009; 136(10): 1591 - 1604. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. McGrew, A. Sherman, S. G. Lillico, F. M. Ellard, P. A. Radcliffe, H. J. Gilhooley, K. A. Mitrophanous, N. Cambray, V. Wilson, and H. Sang Localised axial progenitor cell populations in the avian tail bud are not committed to a posterior Hox identity Development, July 1, 2008; 135(13): 2289 - 2299. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ohta, K. Suzuki, K. Tachibana, H. Tanaka, and G. Yamada Cessation of gastrulation is mediated by suppression of epithelial-mesenchymal transition at the ventral ectodermal ridge Development, December 15, 2007; 134(24): 4315 - 4324. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Brenner-Anantharam, C. Cebrian, R. Guillaume, R. Hurtado, T.-T. Sun, and D. Herzlinger Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling Development, May 15, 2007; 134(10): 1967 - 1975. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Iimura, X. Yang, C. J. Weijer, and O. Pourquie Dual mode of paraxial mesoderm formation during chick gastrulation PNAS, February 20, 2007; 104(8): 2744 - 2749. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Delfino-Machin, J. S. Lunn, D. N. Breitkreuz, J. Akai, and K. G. Storey Specification and maintenance of the spinal cord stem zone Development, October 1, 2005; 132(19): 4273 - 4283. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Dubrulle and O. Pourquie Coupling segmentation to axis formation Development, December 1, 2004; 131(23): 5783 - 5793. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Cambray and V. Wilson Axial progenitors with extensive potency are localised to the mouse chordoneural hinge Development, March 12, 2003; 129(20): 4855 - 4866. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. de Santa Barbara and D. J. Roberts Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13 Development, January 2, 2002; 129(3): 551 - 561. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Davis and M. Kirschner The fate of cells in the tailbud of Xenopus laevis Development, January 1, 2000; 127(2): 255 - 267. [Abstract] [PDF]
|
|
|
|
|
|
J. Charrier, M. Teillet, F Lapointe, and N. Le Douarin Defining subregions of Hensen's node essential for caudalward movement, midline development and cell survival Development, January 11, 1999; 126(21): 4771 - 4783. [Abstract] [PDF]
|
|
|
|
|
|
S. Connors, J Trout, M Ekker, and M. Mullins The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo Development, January 6, 1999; 126(14): 3119 - 3130. [Abstract] [PDF]
|
|
