|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 125, Issue 15 2943-2950, Copyright © 1998 by Company of Biologists
JOURNAL ARTICLES |
W Fu, H Duan, E Frei and M Noll
Institute for Molecular Biology, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.
We have previously shown that the sparkling gene, which like mammalian Pax2 plays an important role in eye development, is encoded by the Drosophila homolog of Pax2. Here we demonstrate that D-Pax2 also encodes the shaven function, which is crucial during bristle development. Both sv and spa alleles, previously thought to represent different genes, are mutations in two widely separated enhancers of D-Pax2. The sv function of D-Pax2 acts in at least two distinct steps of mechanosensory bristle development: the specification of the alternative fate of shaft as opposed to socket cell, and later the differentiation of the shaft cell.
This article has been cited by other articles:
|
|
 |
|
  A. L. Adamson, N. Wright, and D. R. LaJeunesse Modeling Early Epstein-Barr Virus Infection in Drosophila melanogaster: The BZLF1 Protein Genetics, November 1, 2005; 171(3): 1125 - 1135. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Hadrys, R. DeSalle, S. Sagasser, N. Fischer, and B. Schierwater The Trichoplax PaxB Gene: A Putative Proto-PaxA/B/C Gene Predating the Origin of Nerve and Sensory Cells Mol. Biol. Evol., July 1, 2005; 22(7): 1569 - 1578. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Wildonger and R. S. Mann The t(8;21) translocation converts AML1 into a constitutive transcriptional repressor Development, May 15, 2005; 132(10): 2263 - 2272. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Blanco, F. Girard, Y. Kamachi, H. Kondoh, and W. J. Gehring Functional analysis of the chicken {delta}1-crystallin enhancer activity in Drosophila reveals remarkable evolutionary conservation between chicken and fly Development, April 15, 2005; 132(8): 1895 - 1905. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Jafar-Nejad and H. J. Bellen Gfi/Pag-3/Senseless Zinc Finger Proteins: a Unifying Theme? Mol. Cell. Biol., October 15, 2004; 24(20): 8803 - 8812. [Full Text] [PDF]
|
|
|
|
 |
|
 J. Piatigorsky Gene Sharing, Lens Crystallins and Speculations on an Eye/Ear Evolutionary Relationship Integr. Comp. Biol., August 1, 2003; 43(4): 492 - 499. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Kronhamn, E. Frei, M. Daube, R. Jiao, Y. Shi, M. Noll, and A. Rasmuson-Lestander Headless flies produced by mutations in the paralogous Pax6 genes eyeless and twin of eyeless Development, March 4, 2003; 129(4): 1015 - 1026. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Jiao, M. Daube, H. Duan, Y. Zou, E. Frei, and M. Noll Headless flies generated by developmental pathway interference Development, September 1, 2001; 128(17): 3307 - 3319. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. D. Johnson, D. Fitzsimmons, J. Hagman, and H. M. Chamberlin EGL-38 Pax regulates the ovo-related gene lin-48 during Caenorhabditis elegans organ development Development, August 1, 2001; 128(15): 2857 - 2865. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Ben-Yaacov, R. Le Borgne, I. Abramson, F. Schweisguth, and E. D. Schejter Wasp, the Drosophila Wiskott-Aldrich Syndrome Gene Homologue, Is Required for Cell Fate Decisions Mediated by Notch Signaling J. Cell Biol., January 2, 2001; 152(1): 1 - 14. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Locke, L. Podemski, N. Aippersbach, H. Kemp, and R. Hodgetts A Physical Map of the Polytenized Region (101EF-102F) of Chromosome 4 in Drosophila melanogaster Genetics, July 1, 2000; 155(3): 1175 - 1183. [Abstract] [Full Text]
|
|
|
|
|
|
B. Riley, M Chiang, L Farmer, and R Heck The deltaA gene of zebrafish mediates lateral inhibition of hair cells in the inner ear and is regulated by pax2.1 Development, January 12, 1999; 126(24): 5669 - 5678. [Abstract] [PDF]
|
|
|
|
|
|
J Kavaler, W Fu, H Duan, M Noll, and J. Posakony An essential role for the Drosophila Pax2 homolog in the differentiation of adult sensory organs Development, January 5, 1999; 126(10): 2261 - 2272. [Abstract] [PDF]
|
|
