|
|
|
|
|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | ||||
Development, Vol 125, Issue 22 4575-4583, Copyright © 1998 by Company of Biologists
JOURNAL ARTICLES |
T Jaffredo, R Gautier, A Eichmann and F Dieterlen-Lievre
Institut d'Embryologie Cellulaire et Moleculaire du CNRS et du College de France; 49 bis, Avenue de la Belle Gabrielle, France. jaffredo@infobiogen.fr
We have investigated the developmental relationship of the hemopoietic and endothelial lineages in the floor of the chicken aorta, a site of hemopoietic progenitor emergence in the embryo proper. We show that, prior to the onset of hemopoiesis, the aortic endothelium uniformly expresses the endothelium-specific membrane receptor VEGF-R2. The onset of hemopoiesis can be determined by detecting the common leukocyte antigen CD45. VEGF-R2 and CD45 are expressed in complementary fashion, namely the hemopoietic cluster-bearing floor of the aorta is CD45(+)/VEGF-R2(-), while the rest of the aortic endothelium is CD45(-)/VEGF-R2(+). To determine if the hemopoietic clusters are derived from endothelial cells, we tagged the E2 endothelial tree from the inside with low-density lipoproteins (LDL) coupled to DiI. 24 hours later, hemopoietic clusters were labelled by LDL. Since no CD45(+) cells were inserted among endothelial cells at the time of vascular labelling, hemopoietic clusters must be concluded to derive from precursors with an endothelial phenotype.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  M. Peeters, K. Ottersbach, K. Bollerot, C. Orelio, M. de Bruijn, M. Wijgerde, and E. Dzierzak Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development Development, August 1, 2009; 136(15): 2613 - 2621. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. A. Speck, M. Chen, T. Yokomizo, B. Zeigler, and E. Dzierzak Runx1 Interactions in Stem Cell Biology. Blood (ASH Annual Meeting Abstracts), November 16, 2008; 112(11): sci-15 - sci-15. [Abstract]
|
|
|
|
|
|
O. Kazanskaya, B. Ohkawara, M. Heroult, W. Wu, N. Maltry, H. G. Augustin, and C. Niehrs The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development Development, November 15, 2008; 135(22): 3655 - 3664. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H.-T. Huang and L.I. Zon Regulation of Stem Cells in the Zebra Fish Hematopoietic System Cold Spring Harb Symp Quant Biol, November 6, 2008; (2008) sqb.2008.73.029v1. [Abstract] [PDF]
|
|
|
|
 |
|
 M.-J. Yoon, B.-K. Koo, R. Song, H.-W. Jeong, J. Shin, Y.-W. Kim, Y.-Y. Kong, and P.-G. Suh Mind bomb-1 Is Essential for Intraembryonic Hematopoiesis in the Aortic Endothelium and the Subaortic Patches Mol. Cell. Biol., August 1, 2008; 28(15): 4794 - 4804. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Dzierzak and A. Medvinsky The discovery of a source of adult hematopoietic cells in the embryo Development, July 15, 2008; 135(14): 2343 - 2346. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Y. Bertrand, A. D. Kim, S. Teng, and D. Traver CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis Development, May 15, 2008; 135(10): 1853 - 1862. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. J. Jokubaitis, L. Sinka, R. Driessen, G. Whitty, D. N. Haylock, I. Bertoncello, I. Smith, B. Peault, M. Tavian, and P. J. Simmons Angiotensin-converting enzyme (CD143) marks hematopoietic stem cells in human embryonic, fetal, and adult hematopoietic tissues Blood, April 15, 2008; 111(8): 4055 - 4063. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Durand, C. Robin, K. Bollerot, M. H. Baron, K. Ottersbach, and E. Dzierzak Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells PNAS, December 26, 2007; 104(52): 20838 - 20843. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Martinez-Agosto, H. K.A. Mikkola, V. Hartenstein, and U. Banerjee The hematopoietic stem cell and its niche: a comparative view Genes & Dev., December 1, 2007; 21(23): 3044 - 3060. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Pimanda, K. Ottersbach, K. Knezevic, S. Kinston, W. Y. I. Chan, N. K. Wilson, J.-R. Landry, A. D. Wood, A. Kolb-Kokocinski, A. R. Green, et al. Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development PNAS, November 6, 2007; 104(45): 17692 - 17697. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Taoudi and A. Medvinsky Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta PNAS, May 29, 2007; 104(22): 9399 - 9403. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Shinoda, K. Umeda, T. Heike, M. Arai, A. Niwa, F. Ma, H. Suemori, H. Y. Luo, D. H. K. Chui, R. Torii, et al. {alpha}4-Integrin+ endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells Blood, March 15, 2007; 109(6): 2406 - 2415. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Dai, H. Sakamoto, Y. Shimoda, T. Fujimoto, S.-I. Nishikawa, and M. Ogawa Over-expression of c-Myb increases the frequency of hemogenic precursors in the endothelial cell population. Genes Cells, August 1, 2006; 11(8): 859 - 870. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A. Cuadros, A. M. Santos, D. Martin-Oliva, R. Calvente, M. Tassi, J. L. Marin-Teva, and J. Navascues Specific Immunolabeling of Brain Macrophages and Microglial Cells in the Developing and Mature Chick Central Nervous System J. Histochem. Cytochem., June 1, 2006; 54(6): 727 - 738. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Zengin, F. Chalajour, U. M. Gehling, W. D. Ito, H. Treede, H. Lauke, J. Weil, H. Reichenspurner, N. Kilic, and S. Ergun Vascular wall resident progenitor cells: a source for postnatal vasculogenesis Development, April 15, 2006; 133(8): 1543 - 1551. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Pouget, R. Gautier, M.-A. Teillet, and T. Jaffredo Somite-derived cells replace ventral aortic hemangioblasts and provide aortic smooth muscle cells of the trunk Development, March 15, 2006; 133(6): 1013 - 1022. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Esner, S. M. Meilhac, F. Relaix, J.-F. Nicolas, G. Cossu, and M. E. Buckingham Smooth muscle of the dorsal aorta shares a common clonal origin with skeletal muscle of the myotome Development, February 15, 2006; 133(4): 737 - 749. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Sainz, A. Al Haj Zen, G. Caligiuri, C. Demerens, D. Urbain, M. Lemitre, and A. Lafont Isolation of "Side Population" Progenitor Cells From Healthy Arteries of Adult Mice Arterioscler Thromb Vasc Biol, February 1, 2006; 26(2): 281 - 286. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Li, M. J. Chen, T. Stacy, and N. A. Speck Runx1 function in hematopoiesis is required in cells that express Tek Blood, January 1, 2006; 107(1): 106 - 110. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Taoudi, A. M. Morrison, H. Inoue, R. Gribi, J. Ure, and A. Medvinsky Progressive divergence of definitive haematopoietic stem cells from the endothelial compartment does not depend on contact with the foetal liver Development, September 15, 2005; 132(18): 4179 - 4191. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Hirai, I. M Samokhvalov, T. Fujimoto, S. Nishikawa, J. Imanishi, and S.-I. Nishikawa Involvement of Runx1 in the down-regulation of fetal liver kinase-1 expression during transition of endothelial cells to hematopoietic cells Blood, September 15, 2005; 106(6): 1948 - 1955. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Kobayashi-Osaki, O. Ohneda, N. Suzuki, N. Minegishi, T. Yokomizo, S. Takahashi, K.-C. Lim, J. D. Engel, and M. Yamamoto GATA Motifs Regulate Early Hematopoietic Lineage-Specific Expression of the Gata2 Gene Mol. Cell. Biol., August 15, 2005; 25(16): 7005 - 7020. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. T. Zambidis, B. Peault, T. S. Park, F. Bunz, and C. I. Civin Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development Blood, August 1, 2005; 106(3): 860 - 870. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Y. Bertrand, S. Giroux, R. Golub, M. Klaine, A. Jalil, L. Boucontet, I. Godin, and A. Cumano Characterization of purified intraembryonic hematopoietic stem cells as a tool to define their site of origin PNAS, January 4, 2005; 102(1): 134 - 139. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Stadtfeld and T. Graf Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing Development, January 1, 2005; 132(1): 203 - 213. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Tagliafico, S. Brunelli, A. Bergamaschi, L. De Angelis, R. Scardigli, D. Galli, R. Battini, P. Bianco, S. Ferrari, G. Cossu, et al. TGF{beta}/BMP activate the smooth muscle/bone differentiation programs in mesoangioblasts J. Cell Sci., September 1, 2004; 117(19): 4377 - 4388. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Vokes, T. A. Yatskievych, R. L. Heimark, J. McMahon, A. P. McMahon, P. B. Antin, and P. A. Krieg Hedgehog signaling is essential for endothelial tube formation during vasculogenesis Development, September 1, 2004; 131(17): 4371 - 4380. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Suzuki, Y. Komi, H. Ashino, J. Yamashita, J. Inoue, A. Yoshiki, A. Eichmann, H. Amanuma, and S. Kojima Retinoic acid controls blood vessel formation by modulating endothelial and mural cell interaction via suppression of Tie2 signaling in vascular progenitor cells Blood, July 1, 2004; 104(1): 166 - 169. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Gottgens, C. Broccardo, M.-J. Sanchez, S. Deveaux, G. Murphy, J. R. Gothert, E. Kotsopoulou, S. Kinston, L. Delaney, S. Piltz, et al. The scl +18/19 Stem Cell Enhancer Is Not Required for Hematopoiesis: Identification of a 5' Bifunctional Hematopoietic-Endothelial Enhancer Bound by Fli-1 and Elf-1 Mol. Cell. Biol., March 1, 2004; 24(5): 1870 - 1883. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Gering, Y. Yamada, T. H. Rabbitts, and R. K. Patient Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1 Development, December 22, 2003; 130(25): 6187 - 6199. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Alvarez-Silva, P. Belo-Diabangouaya, J. Salaun, and F. Dieterlen-Lievre Mouse placenta is a major hematopoietic organ Development, November 15, 2003; 130(22): 5437 - 5444. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Sugiyama, M. Ogawa, I. Hirose, T. Jaffredo, K.-i. Arai, and K. Tsuji Erythropoiesis from acetyl LDL incorporating endothelial cells at the preliver stage Blood, June 15, 2003; 101(12): 4733 - 4738. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. L. S. Sequeira Lopez, D. R. Chernavvsky, T. Nomasa, L. Wall, M. Yanagisawa, and R. A. Gomez The embryo makes red blood cell progenitors in every tissue simultaneously with blood vessel morphogenesis Am J Physiol Regulatory Integrative Comp Physiol, April 1, 2003; 284(4): R1126 - R1137. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L. Kalev-Zylinska, J. A. Horsfield, M. V. C. Flores, J. H. Postlethwait, M. R. Vitas, A. M. Baas, P. S. Crosier, and K. E. Crosier Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis Development, March 6, 2003; 129(8): 2015 - 2030. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Kubo and K. Alitalo The bloody fate of endothelial stem cells Genes & Dev., February 1, 2003; 17(3): 322 - 329. [Full Text] [PDF]
|
|
|
|
|
|
H. Hirai, M. Ogawa, N. Suzuki, M. Yamamoto, G. Breier, O. Mazda, J. Imanishi, and S.-I. Nishikawa Hemogenic and nonhemogenic endothelium can be distinguished by the activity of fetal liver kinase (Flk)-1 promoter/enhancer during mouse embryogenesis Blood, February 1, 2003; 101(3): 886 - 893. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. J. Chen, G. Zhou, T. Juan, S. M. Colicos, J. P. Cannon, M. Cabriera-Hansen, C. F. Meyer, R. Jurecic, N. G. Copeland, D. J. Gilbert, et al. The Dual Specificity JKAP Specifically Activates the c-Jun N-terminal Kinase Pathway J. Biol. Chem., September 20, 2002; 277(39): 36592 - 36601. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Oberlin, M. Tavian, I. Blazsek, and B. Peault Blood-forming potential of vascular endothelium in the human embryo Development, September 1, 2002; 129(17): 4147 - 4157. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Graf Differentiation plasticity of hematopoietic cells Blood, May 1, 2002; 99(9): 3089 - 3101. [Full Text] [PDF]
|
|
|
|
|
|
K.-i. Minehata, Y.-s. Mukouyama, T. Sekiguchi, T. Hara, and A. Miyajima Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region Blood, April 1, 2002; 99(7): 2360 - 2368. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. G. Minasi, M. Riminucci, L. De Angelis, U. Borello, B. Berarducci, A. Innocenzi, A. Caprioli, D. Sirabella, M. Baiocchi, R. De Maria, et al. The meso-angioblast: a multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues Development, January 6, 2002; 129(11): 2773 - 2783. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Vokes and P. A. Krieg Endoderm is required for vascular endothelial tube formation, but not for angioblast specification Development, January 2, 2002; 129(3): 775 - 785. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Ausoni and S. Sartore Cell Lineages and Tissue Boundaries in Cardiac Arterial and Venous Poles : Developmental Patterns, Animal Models, and Implications for Congenital Vascular Diseases Arterioscler Thromb Vasc Biol, March 1, 2001; 21(3): 312 - 320. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P Faloon, E Arentson, A Kazarov, C. Deng, C Porcher, S Orkin, and K Choi Basic fibroblast growth factor positively regulates hematopoietic development Development, January 5, 2000; 127(9): 1931 - 1941. [Abstract] [PDF]
|
|
|
|
|
|
Y. Yamada, R. Pannell, A. Forster, and T. H. Rabbitts The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice PNAS, January 4, 2000; 97(1): 320 - 324. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. G. Elefanty, C. G. Begley, L. Hartley, B. Papaevangeliou, and L. Robb SCL Expression in the Mouse Embryo Detected With a Targeted lacZ Reporter Gene Demonstrates Its Localization to Hematopoietic, Vascular, and Neural Tissues Blood, December 1, 1999; 94(11): 3754 - 3763. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. P. Ordahl Myogenic Shape-Shifters J. Cell Biol., November 15, 1999; 147(4): 695 - 698. [Full Text] [PDF]
|
|
|
|
|
|
C Porcher, E. Liao, Y Fujiwara, L. Zon, and S. Orkin Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding Development, January 10, 1999; 126(20): 4603 - 4615. [Abstract] [PDF]
|
|
|
|
|
|
M Sanchez, B Gottgens, A. Sinclair, M Stanley, C. Begley, S Hunter, and A. Green An SCL 3' enhancer targets developing endothelium together with embryonic and adult haematopoietic progenitors Development, January 9, 1999; 126(17): 3891 - 3904. [Abstract] [PDF]
|
|
|
|
|
|
T North, T. Gu, T Stacy, Q Wang, L Howard, M Binder, M Marin-Padilla, and N. Speck Cbfa2 is required for the formation of intra-aortic hematopoietic clusters Development, January 6, 1999; 126(11): 2563 - 2575. [Abstract] [PDF]
|
|
|
|
|
|
L Parker and D. Stainier Cell-autonomous and non-autonomous requirements for the zebrafish gene cloche in hematopoiesis Development, January 6, 1999; 126(12): 2643 - 2651. [Abstract] [PDF]
|
|
