spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Newsome, T. P.
Right arrow Articles by Dickson, B. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Newsome, T. P.
Right arrow Articles by Dickson, B. J.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Development, Vol 127, Issue 4 851-860, Copyright © 2000 by Company of Biologists

JOURNAL ARTICLES

Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics

TP Newsome, B Asling and BJ Dickson
Research Institute of Molecular Pathology, Dr Bohr-Gasse 7, A-1030 Vienna, Austria.

During development of the adult Drosophila visual system, axons of the eight photoreceptors in each ommatidium fasciculate together and project as a single bundle towards the optic lobes of the brain. Within the brain, individual photoreceptor axons from each bundle then seek specific targets in distinct layers of the optic lobes. The axons of photoreceptors R1-R6 terminate in the lamina, while R7 and R8 axons pass through the lamina to terminate in separate layers of the medulla. To identify genes required for photoreceptor axon guidance, including those with essential functions during early development, we have devised a strategy for the simple and efficient generation of genetic mosaics in which mutant photoreceptor axons innervate a predominantly wild-type brain. In a large-scale saturation mutagenesis performed using this system, we recovered new alleles of the gene encoding the receptor tyrosine phosphatase PTP69D. PTP69D has previously been shown to function in the correct targeting of motor axons in the embryo and R1-R6 axons in the visual system. Here, we show that PTP69D is also required for correct targeting of R7 axons. Whereas mutant R1-R6 axons occasionally extend beyond their normal targets in the lamina, mutant R7 axons often fail to reach their targets in the medulla, stopping instead at the same level as the R8 axon. These targeting errors are difficult to reconcile with models in which PTP69D plays an instructive role in photoreceptor axon targeting, as previously proposed. Rather, we suggest that PTP69D plays a permissive role, perhaps reducing the adhesion of R1-R6 and R7 growth cones to the pioneer R8 axon so that they can respond independently to their specific targeting cues.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
K. Hofmeyer and J. E. Treisman
The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism
PNAS, November 17, 2009; 106(46): 19399 - 19404.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. Ferguson, H. Long, S. Cameron, W.-T. Chang, and Y. Rao
The Conserved Ig Superfamily Member Turtle Mediates Axonal Tiling in Drosophila
J. Neurosci., November 11, 2009; 29(45): 14151 - 14159.
[Abstract] [Full Text] [PDF]

Home page
 Cold Spring Harb. Perspect. Biol.Home page
N. Giagtzoglou, C. V. Ly, and H. J. Bellen
Cell Adhesion, the Backbone of the Synapse: "Vertebrate" and "Invertebrate" Perspectives
Cold Spring Harb Perspect Biol, October 1, 2009; 1(4): a003079 - a003079.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
A. M. Ambrus, V. I. Rasheva, B. N. Nicolay, and M. V. Frolov
Mosaic Genetic Screen for Suppressors of the de2f1 Mutant Phenotype in Drosophila
Genetics, September 1, 2009; 183(1): 79 - 92.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
T. Vaccari, T. E. Rusten, L. Menut, I. P. Nezis, A. Brech, H. Stenmark, and D. Bilder
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J. Cell Sci., July 15, 2009; 122(14): 2413 - 2423.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
N. Giagtzoglou, Y. Q. Lin, C. Haueter, and H. J. Bellen
Importin 13 Regulates Neurotransmitter Release at the Drosophila Neuromuscular Junction
J. Neurosci., April 29, 2009; 29(17): 5628 - 5639.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
D. A. Birkholz, W.-H. Chou, M. M. Phistry, and S. G. Britt
rhomboid Mediates Specification of Blue- and Green-Sensitive R8 Photoreceptor Cells in Drosophila
J. Neurosci., March 4, 2009; 29(9): 2666 - 2675.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
C. L. Simpson, R. Lemmens, K. Miskiewicz, W. J. Broom, V. K. Hansen, P. W.J. van Vught, J. E. Landers, P. Sapp, L. Van Den Bosch, J. Knight, et al.
Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration
Hum. Mol. Genet., February 1, 2009; 18(3): 472 - 481.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
R. Martin, P. Smibert, A. Yalcin, D. M. Tyler, U. Schafer, T. Tuschl, and E. C. Lai
A Drosophila pasha Mutant Distinguishes the Canonical MicroRNA and Mirtron Pathways
Mol. Cell. Biol., February 1, 2009; 29(3): 861 - 870.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
D. Melicharek, A. Shah, G. DiStefano, A. J. Gangemi, A. Orapallo, A. D. Vrailas-Mortimer, and D. R. Marenda
Identification of Novel Regulators of atonal Expression in the Developing Drosophila Retina
Genetics, December 1, 2008; 180(4): 2095 - 2110.
[Abstract] [Full Text] [PDF]

Home page
 J. Exp. Biol.Home page
J. Borycz, J. A. Borycz, A. Kubow, V. Lloyd, and I. A. Meinertzhagen
Drosophila ABC transporter mutants white, brown and scarlet have altered contents and distribution of biogenic amines in the brain
J. Exp. Biol., November 1, 2008; 211(21): 3454 - 3466.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
A.-C. Tien, A. Rajan, K. L. Schulze, H. D. Ryoo, M. Acar, H. Steller, and H. J. Bellen
Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster
J. Cell Biol., September 22, 2008; 182(6): 1113 - 1125.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
J. D. Mast, K. M. H. Tomalty, H. Vogel, and T. R. Clandinin
Reactive oxygen species act remotely to cause synapse loss in a Drosophila model of developmental mitochondrial encephalopathy
Development, August 1, 2008; 135(15): 2669 - 2679.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
M. R. Spasic, P. Callaerts, and K. K. Norga
Drosophila alicorn Is a Neuronal Maintenance Factor Protecting against Activity-Induced Retinal Degeneration
J. Neurosci., June 18, 2008; 28(25): 6419 - 6429.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
N. A. Bulgakova, O. Kempkens, and E. Knust
Multiple domains of Stardust differentially mediate localisation of the Crumbs-Stardust complex during photoreceptor development in Drosophila
J. Cell Sci., June 15, 2008; 121(12): 2018 - 2026.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
C. V. Ly, C.-K. Yao, P. Verstreken, T. Ohyama, and H. J. Bellen
straightjacket is required for the synaptic stabilization of cacophony, a voltage-gated calcium channel {alpha}1 subunit
J. Cell Biol., April 3, 2008; 181(1): 157 - 170.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
H. Benchabane, E. G. Hughes, C. M. Takacs, J. R. Baird, and Y. Ahmed
Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen
Development, March 1, 2008; 135(5): 963 - 971.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
T. Vaccari, H. Lu, R. Kanwar, M. E. Fortini, and D. Bilder
Endosomal entry regulates Notch receptor activation in Drosophila melanogaster
J. Cell Biol., February 25, 2008; 180(4): 755 - 762.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
A. C. Miller, H. Seymour, C. King, and T. G. Herman
Loss of seven-up from Drosophila R1/R6 photoreceptors reveals a stochastic fate choice that is normally biased by Notch
Development, February 15, 2008; 135(4): 707 - 715.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
T. V. Lee, T. Ding, Z. Chen, V. Rajendran, H. Scherr, M. Lackey, C. Bolduc, and A. Bergmann
The E1 ubiquitin-activating enzyme Uba1 in Drosophila controls apoptosis autonomously and tissue growth non-autonomously
Development, January 1, 2008; 135(1): 43 - 52.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
R. V. Barkus, O. Klyachko, D. Horiuchi, B. J. Dickson, and W. M. Saxton
Identification of an Axonal Kinesin-3 Motor for Fast Anterograde Vesicle Transport that Facilitates Retrograde Transport of Neuropeptides
Mol. Biol. Cell, January 1, 2008; 19(1): 274 - 283.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
T. Ohyama, P. Verstreken, C. V. Ly, T. Rosenmund, A. Rajan, A.-C. Tien, C. Haueter, K. L. Schulze, and H. J. Bellen
Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles
J. Cell Biol., December 31, 2007; 179(7): 1481 - 1496.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
L. Menut, T. Vaccari, H. Dionne, J. Hill, G. Wu, and D. Bilder
A Mosaic Genetic Screen for Drosophila Neoplastic Tumor Suppressor Genes Based on Defective Pupation
Genetics, November 1, 2007; 177(3): 1667 - 1677.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
S. Berger, N. A. Bulgakova, F. Grawe, K. Johnson, and E. Knust
Unraveling the Genetic Complexity of Drosophila stardust During Photoreceptor Morphogenesis and Prevention of Light-Induced Degeneration
Genetics, August 1, 2007; 176(4): 2189 - 2200.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
E. N. Mindorff, D. D. O'Keefe, A. Labbe, J. P. Yang, Y. Ou, S. Yoshikawa, and D. J. van Meyel
A Gain-of-Function Screen for Genes That Influence Axon Guidance Identifies the NF-{kappa}B Protein Dorsal and Reveals a Requirement for the Kinase Pelle in Drosophila Photoreceptor Axon Targeting
Genetics, August 1, 2007; 176(4): 2247 - 2263.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
V. Hietakangas and S. M. Cohen
Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth
Genes & Dev., March 15, 2007; 21(6): 632 - 637.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
R. Nagaraj and U. Banerjee
Combinatorial signaling in the specification of primary pigment cells in the Drosophila eye
Development, March 1, 2007; 134(5): 825 - 831.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
D. M. Tyler, W. Li, N. Zhuo, B. Pellock, and N. E. Baker
Genes Affecting Cell Competition in Drosophila
Genetics, February 1, 2007; 175(2): 643 - 657.
[Abstract] [Full Text] [PDF]

Home page
 RNAHome page
K. Kim, Y. S. Lee, and R. W. Carthew
Conversion of pre-RISC to holo-RISC by Ago2 during assembly of RNAi complexes
RNA, January 1, 2007; 13(1): 22 - 29.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
A. Singh, X. Shi, and K.-W. Choi
Lobe and Serrate are required for cell survival during early eye development in Drosophila.
Development, December 1, 2006; 133(23): 4771 - 4781.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
L. A. Ekas, G.-H. Baeg, M. S. Flaherty, A. Ayala-Camargo, and E. A. Bach
JAK/STAT signaling promotes regional specification by negatively regulating wingless expression in Drosophila
Development, December 1, 2006; 133(23): 4721 - 4729.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
C. Bras-Pereira, J. Bessa, and F. Casares
Odd-skipped genes specify the signaling center that triggers retinogenesis in Drosophila
Development, November 1, 2006; 133(21): 4145 - 4149.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
S. Kondo, N. Senoo-Matsuda, Y. Hiromi, and M. Miura
DRONC Coordinates Cell Death and Compensatory Proliferation.
Mol. Cell. Biol., October 1, 2006; 26(19): 7258 - 7268.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
T. S. V. Liao, G. B. Call, P. Guptan, A. Cespedes, J. Marshall, K. Yackle, E. Owusu-Ansah, S. Mandal, Q. A. Fang, G. L. Goodstein, et al.
An Efficient Genetic Screen in Drosophila to Identify Nuclear-Encoded Genes With Mitochondrial Function
Genetics, September 1, 2006; 174(1): 525 - 533.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
I. Mirkovic and M. Mlodzik
Cooperative activities of Drosophila DE-Cadherin and DN-Cadherin regulate the cell motility process of ommatidial rotation
Development, September 1, 2006; 133(17): 3283 - 3293.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
T. E. Rusten, L. M.W. Rodahl, K. Pattni, C. Englund, C. Samakovlis, S. Dove, A. Brech, and H. Stenmark
Fab1 Phosphatidylinositol 3-Phosphate 5-Kinase Controls Trafficking but Not Silencing of Endocytosed Receptors
Mol. Biol. Cell, September 1, 2006; 17(9): 3989 - 4001.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
N. R. Orem, L. Xia, and P. J. Dolph
An essential role for endocytosis of rhodopsin through interaction of visual arrestin with the AP-2 adaptor
J. Cell Sci., August 1, 2006; 119(15): 3141 - 3148.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. Hofmeyer, C. Maurel-Zaffran, H. Sink, and J. E. Treisman
Liprin-{alpha} has LAR-independent functions in R7 photoreceptor axon targeting
PNAS, August 1, 2006; 103(31): 11595 - 11600.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
K. M. Hennig, J. Colombani, and T. P. Neufeld
TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth
J. Cell Biol., June 19, 2006; 173(6): 963 - 974.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
C. Jones, R. Reifegerste, and K. Moses
Characterization of Drosophila mini-me, a Gene Required for Cell Proliferation and Survival
Genetics, June 1, 2006; 173(2): 793 - 808.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
N. Uetani, M. J. Chagnon, T. E. Kennedy, Y. Iwakura, and M. L. Tremblay
Mammalian motoneuron axon targeting requires receptor protein tyrosine phosphatases sigma and delta.
J. Neurosci., May 31, 2006; 26(22): 5872 - 5880.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
H.-M. Herz, Z. Chen, H. Scherr, M. Lackey, C. Bolduc, and A. Bergmann
vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis
Development, May 15, 2006; 133(10): 1871 - 1880.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M. Acar, H. Jafar-Nejad, N. Giagtzoglou, S. Yallampalli, G. David, Y. He, C. Delidakis, and H. J. Bellen
Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator
Development, May 15, 2006; 133(10): 1979 - 1989.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
V. I. Rasheva, D. Knight, P. Bozko, K. Marsh, and M. V. Frolov
Specific Role of the SR Protein Splicing Factor B52 in Cell Cycle Control in Drosophila.
Mol. Cell. Biol., May 1, 2006; 26(9): 3468 - 3477.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
P. Cafferty, L. Yu, H. Long, and Y. Rao
Semaphorin-1a Functions as a Guidance Receptor in the Drosophila Visual System
J. Neurosci., April 12, 2006; 26(15): 3999 - 4003.
[Abstract] [Full Text] [PDF]

Home page
 Cold Spring Harb Symp Quant BiolHome page
K. KIM, Y.S. LEE, D. HARRIS, K. NAKAHARA, and R.W. CARTHEW
The RNAi Pathway Initiated by Dicer-2 in Drosophila
Cold Spring Harb Symp Quant Biol, January 1, 2006; 71(0): 39 - 44.
[Abstract] [PDF]

Home page
 GeneticsHome page
P. Geuking, R. Narasimamurthy, and K. Basler
A Genetic Screen Targeting the Tumor Necrosis Factor/Eiger Signaling Pathway: Identification of Drosophila TAB2 as a Functionally Conserved Component
Genetics, December 1, 2005; 171(4): 1683 - 1694.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
I. Delalle, C. M. Pfleger, E. Buff, P. Lueras, and I. K. Hariharan
Mutations in the Drosophila Orthologs of the F-Actin Capping Protein {alpha}- and {beta}-Subunits Cause Actin Accumulation and Subsequent Retinal Degeneration
Genetics, December 1, 2005; 171(4): 1757 - 1765.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
C. M. A. Coelho, B. Kolevski, C. D. Walker, I. Lavagi, T. Shaw, A. Ebert, S. J. Leevers, and S. J. Marygold
A Genetic Screen for Dominant Modifiers of a Small-Wing Phenotype in Drosophila melanogaster Identifies Proteins Involved in Splicing and Translation
Genetics, October 1, 2005; 171(2): 597 - 614.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
M. Uhlirova, H. Jasper, and D. Bohmann
Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor model
PNAS, September 13, 2005; 102(37): 13123 - 13128.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Nern, L.-V. T. Nguyen, T. Herman, S. Prakash, T. R. Clandinin, and S. L. Zipursky
From The Cover: An isoform-specific allele of Drosophila N-cadherin disrupts a late step of R7 targeting
PNAS, September 6, 2005; 102(36): 12944 - 12949.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
A. Singh, J. Chan, J. J. Chern, and K.-W. Choi
Genetic Interaction of Lobe With Its Modifiers in Dorsoventral Patterning and Growth of the Drosophila Eye
Genetics, September 1, 2005; 171(1): 169 - 183.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
B. Dermaut, K. K. Norga, A. Kania, P. Verstreken, H. Pan, Y. Zhou, P. Callaerts, and H. J. Bellen
Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer
J. Cell Biol., July 4, 2005; 170(1): 127 - 139.
[Abstract] [Full Text] [PDF]

Home page
 GENES CELLSHome page
M. Iwanami, Y. Hiromi, and M. Okabe
Cell-type specific utilization of multiple negative feedback loops generates developmental constancy
Genes Cells, July 1, 2005; 10(7): 743 - 752.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
T. Pauli, M. Seimiya, J. Blanco, and W. J. Gehring
Identification of functional sine oculis motifs in the autoregulatory element of its own gene, in the eyeless enhancer and in the signalling gene hedgehog
Development, June 15, 2005; 132(12): 2771 - 2782.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
D. C. I. Goberdhan, D. Meredith, C. A. R. Boyd, and C. Wilson
PAT-related amino acid transporters regulate growth via a novel mechanism that does not require bulk transport of amino acids
Development, May 15, 2005; 132(10): 2365 - 2375.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
D. Xu, Y. Li, M. Arcaro, M. Lackey, and A. Bergmann
The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila
Development, May 1, 2005; 132(9): 2125 - 2134.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
S. Zhu, R. Perez, M. Pan, and T. Lee
Requirement of Cul3 for Axonal Arborization and Dendritic Elaboration in Drosophila Mushroom Body Neurons
J. Neurosci., April 20, 2005; 25(16): 4189 - 4197.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
J. Blanco, F. Girard, Y. Kamachi, H. Kondoh, and W. J. Gehring
Functional analysis of the chicken {delta}1-crystallin enhancer activity in Drosophila reveals remarkable evolutionary conservation between chicken and fly
Development, April 15, 2005; 132(8): 1895 - 1905.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
L. Stepanek, A. W. Stoker, E. Stoeckli, and J. L. Bixby
Receptor Tyrosine Phosphatases Guide Vertebrate Motor Axons during Development
J. Neurosci., April 13, 2005; 25(15): 3813 - 3823.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
C.-Y. Ting, S. Yonekura, P. Chung, S.-n. Hsu, H. M. Robertson, A. Chiba, and C.-H. Lee
Drosophila N-cadherin functions in the first stage of the two-stage layer-selection process of R7 photoreceptor afferents
Development, March 1, 2005; 132(5): 953 - 963.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
J. H. Reiling and E. Hafen
The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila
Genes & Dev., December 1, 2004; 18(23): 2879 - 2892.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
P. M. Domingos, M. Mlodzik, C. S. Mendes, S. Brown, H. Steller, and B. Mollereau
Spalt transcription factors are required for R3/R4 specification and establishment of planar cell polarity in the Drosophila eye
Development, November 15, 2004; 131(22): 5695 - 5702.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
P. Cafferty, L. Yu, and Y. Rao
The receptor tyrosine kinase Off-track is required for layer-specific neuronal connectivity in Drosophila
Development, November 1, 2004; 131(21): 5287 - 5295.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Yang and S. Kunes
Nonvesicular release of acetylcholine is required for axon targeting in the Drosophila visual system
PNAS, October 19, 2004; 101(42): 15213 - 15218.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
J. L. Whited, A. Cassell, M. Brouillette, and P. A. Garrity
Dynactin is required to maintain nuclear position within postmitotic Drosophila photoreceptor neurons
Development, October 1, 2004; 131(19): 4677 - 4686.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
D. Jhaveri, S. Saharan, A. Sen, and V. Rodrigues
Positioning sensory terminals in the olfactory lobe of Drosophila by Robo signaling
Development, May 1, 2004; 131(9): 1903 - 1912.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
G. Gu, J. Yang, K. A. Mitchell, and J. E. O'Tousa
Drosophila NinaB and NinaD Act Outside of Retina to Produce Rhodopsin Chromophore
J. Biol. Chem., April 30, 2004; 279(18): 18608 - 18613.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
C.-D. Hsu, M. A. Whaley, K. Frazer, D. A. Miller, K. A. Mitchell, S. M. Adams, and J. E. O'Tousa
Limited Role of Developmental Programmed Cell Death Pathways in Drosophila norpA Retinal Degeneration
J. Neurosci., January 14, 2004; 24(2): 500 - 507.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
F. Janody, J. D. Lee, N. Jahren, D. J. Hazelett, A. Benlali, G. I. Miura, I. Draskovic, and J. E. Treisman
A Mosaic Genetic Screen Reveals Distinct Roles for trithorax and Polycomb Group Genes in Drosophila Eye Development
Genetics, January 1, 2004; 166(1): 187 - 200.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
A. Singh and K.-W. Choi
Initial state of the Drosophila eye before dorsoventral specification is equivalent to ventral
Development, December 22, 2003; 130(25): 6351 - 6360.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. G. Voas and I. Rebay
The Novel Plant Homeodomain Protein Rhinoceros Antagonizes Ras Signaling in the Drosophila Eye
Genetics, December 1, 2003; 165(4): 1993 - 2006.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
R. Fabian-Fine, P. Verstreken, P. R. Hiesinger, J. A. Horne, R. Kostyleva, Y. Zhou, H. J. Bellen, and I. A. Meinertzhagen
Endophilin Promotes a Late Step in Endocytosis at Glial Invaginations in Drosophila Photoreceptor Terminals
J. Neurosci., November 19, 2003; 23(33): 10732 - 10744.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
M. Morey, M. Corominas, and F. Serras
DIAP1 suppresses ROS-induced apoptosis caused by impairment of the selD/sps1 homolog in Drosophila
J. Cell Sci., November 15, 2003; 116(22): 4597 - 4604.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
R. A. Pagliarini and T. Xu
A Genetic Screen in Drosophila for Metastatic Behavior
Science, November 14, 2003; 302(5648): 1227 - 1231.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
J. Jia, W. Zhang, B. Wang, R. Trinko, and J. Jiang
The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis
Genes & Dev., October 15, 2003; 17(20): 2514 - 2519.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
P. I. z. Lage, D. R. A. Prentice, E. E. Holohan, and A. P. Jarman
The Drosophila proneural gene amos promotes olfactory sensillum formation and suppresses bristle formation
Development, October 1, 2003; 130(19): 4683 - 4693.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
P. D. S. Dong, S. V. Todi, D. F. Eberl, and G. Boekhoff-Falk
Drosophila spalt/spalt-related mutants exhibit Townes-Brocks' syndrome phenotypes
PNAS, September 2, 2003; 100(18): 10293 - 10298.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
J. P. Kumar, F. Hsiung, M. A. Powers, and K. Moses
Nuclear translocation of activated MAP kinase is developmentally regulated in the developing Drosophila eye
Development, August 15, 2003; 130(16): 3703 - 3714.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
E. L. Rawlins, N. M. White, and A. P. Jarman
Echinoid limits R8 photoreceptor specification by inhibiting inappropriate EGF receptor signalling within R8 equivalence groups
Development, August 15, 2003; 130(16): 3715 - 3724.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
F. Rintelen, E. Hafen, and K. Nairz
The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER
Development, August 1, 2003; 130(15): 3479 - 3490.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
C. Desai and J. Purdy
The Neural Receptor Protein Tyrosine Phosphatase DPTP69D Is Required During Periods of Axon Outgrowth in Drosophila
Genetics, June 1, 2003; 164(2): 575 - 588.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
A. Inbal, D. Levanon, and A. Salzberg
Multiple roles for u-turn/ventral veinless in the development of Drosophila PNS
Development, June 1, 2003; 130(11): 2467 - 2478.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
J. Song, L. Wu, Z. Chen, R. A. Kohanski, and L. Pick
Axons Guided by Insulin Receptor in Drosophila Visual System
Science, April 18, 2003; 300(5618): 502 - 505.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
L.-H. Ang, J. Kim, V. Stepensky, and H. Hing
Dock and Pak regulate olfactory axon pathfinding in Drosophila
Development, April 1, 2003; 130(7): 1307 - 1316.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
M. Vegh and K. Basler
A Genetic Screen for Hedgehog Targets Involved in the Maintenance of the Drosophila Anteroposterior Compartment Boundary
Genetics, April 1, 2003; 163(4): 1427 - 1438.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
M. Kango-Singh, R. Nolo, C. Tao, P. Verstreken, P. R. Hiesinger, H. J. Bellen, and G. Halder
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila
Development, March 14, 2003; 129(24): 5719 - 5730.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
K. M. Cadigan, A. D. Jou, and R. Nusse
Wingless blocks bristle formation and morphogenetic furrow progression in the eye through repression of Daughterless
Development, March 9, 2003; 129(14): 3393 - 3402.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
P. D. S. Dong, J. S. Dicks, and G. Panganiban
Distal-less and homothorax regulate multiple targets to pattern the Drosophila antenna
Development, March 6, 2003; 129(8): 1967 - 1974.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
K. G. Johnson and D. Van Vactor
Receptor Protein Tyrosine Phosphatases in Nervous System Development
Physiol Rev, January 1, 2003; 83(1): 1 - 24.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
J. H. Lee, K. S. Cho, J. Lee, D. Kim, S.-B. Lee, J. Yoo, G.-H. Cha, and J. Chung
Drosophila PDZ-GEF, a Guanine Nucleotide Exchange Factor for Rap1 GTPase, Reveals a Novel Upstream Regulatory Mechanism in the Mitogen-Activated Protein Kinase Signaling Pathway
Mol. Cell. Biol., November 1, 2002; 22(21): 7658 - 7666.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
T. Radimerski, J. Montagne, M. Hemmings-Mieszczak, and G. Thomas
Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling
Genes & Dev., October 15, 2002; 16(20): 2627 - 2632.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
C.-Y. Ou, Y.-F. Lin, Y.-J. Chen, and C.-T. Chien
Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development
Genes & Dev., September 15, 2002; 16(18): 2403 - 2414.
[Abstract] [Full Text] [PDF]

Home page
 Genes Dev.Home page
J. Bessa, B. Gebelein, F. Pichaud, F. Casares, and R. S. Mann
Combinatorial control of Drosophila eye development by Eyeless, Homothorax, and Teashirt
Genes & Dev., September 15, 2002; 16(18): 2415 - 2427.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
S. Oldham, H. Stocker, M. Laffargue, F. Wittwer, M. Wymann, and E. Hafen
The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP3 levels
Development, September 1, 2002; 129(17): 4103 - 4109.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
K. D. Curtin, Z. Zhang, and R. J. Wyman
Gap Junction Proteins Expressed during Development Are Required for Adult Neural Function in the Drosophila Optic Lamina
J. Neurosci., August 15, 2002; 22(16): 7088 - 7096.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
K. Nairz, H. Stocker, B. Schindelholz, and E. Hafen
High-resolution SNP mapping by denaturing HPLC
PNAS, August 6, 2002; 99(16): 10575 - 10580.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurosci.Home page
F. Rashid-Doubell, I. McKinnell, A. R. Aricescu, G. Sajnani, and A. Stoker
Chick PTPsigma Regulates the Targeting of Retinal Axons within the Optic Tectum
J. Neurosci., June 15, 2002; 22(12): 5024 - 5033.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
A. R. Aricescu, I. W. McKinnell, W. Halfter, and A. W. Stoker
Heparan Sulfate Proteoglycans Are Ligands for Receptor Protein Tyrosine Phosphatase {sigma}
Mol. Cell. Biol., March 15, 2002; 22(6): 1881 - 1892.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 2000