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Development 128, 4847-4858 (2001)
© 2001 The Company of Biologists Limited

Mutations in LIKE HETEROCHROMATIN PROTEIN 1 affect flowering time and plant architecture in Arabidopsis

Valérie Gaudin1,*, Marc Libault1, Sylvie Pouteau1, Trine Juul1, Gengchun Zhao1,{ddagger}, Delphine Lefebvre1 and Olivier Grandjean2

1 Laboratoire de Biologie Cellulaire,
2 Laboratoire de Génétique, INRA, route de St Cyr, 78026 Versailles cedex, France
{ddagger} Present address: Northeast Normal University, Changchun, China

*Author for correspondence (e-mail: valerie.gaudin{at}versailles.inra.fr)

Accepted August 31, 2001

In plants, recent studies have demonstrated links between the regulation of developmental processes and chromatin dynamics and organisation. Analysis of new mutations affecting overall plant architecture, leaf development and flowering time in Arabidopsis has allowed us to clone and characterise LHP1, the Drosophila heterochromatin protein 1 (HP1) homologue. LHP1 has the chromo and chromo shadow domains central to the function of animal proteins. Yeast two hybrid studies and in planta deletion experiments suggest similar modes of action in plants and animals via homodimer formation. In vivo localisation experiments revealed a specific subnuclear protein distribution in foci throughout the nucleus. Our data suggest that LHP1 may act as a main regulator of gene expression in plants, through formation of heterochromatin-like repressive complexes, to control developmental pathways involved in organ and cell size, and the vegetative to reproductive phase transition.

Key words: Arabidopsis thaliana, Chromatin, HP1, Flowering time, Leaf development




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© The Company of Biologists Ltd 2001