spacer gif spacer gif spacer gif spacer gif ARCHIVE ANNOUNCEMENT! spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online September 2, 2003
doi: 10.1242/10.1242/dev.00701

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in Development
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Yochem, J.
Right arrow Articles by Herman, R. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Yochem, J.
Right arrow Articles by Herman, R. K.
Development 130, 4761-4768 (2003)
Copyright © 2003 The Company of Biologists Limited

PRIMER

Investigating C. elegans development through mosaic analysis

John Yochem and Robert K. Herman

Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street, Minneapolis, MN 55455, USA

SUMMARY

The analysis of genetically mosaic worms, in which some cells carry a wild-type gene and others are homozygous mutant, can reveal where in the animal a gene acts to prevent the appearance of a mutant phenotype. In this primer article, we describe how Caenorhabditis elegans genetic mosaics are generated, identified and analyzed, and we discuss examples in which the analysis of mosaic worms has provided important information about the development of this organism.


Related articles in Development:

Piecing together genetic mosaics

Development 2003 130: 2001. [Full Text]  



This article has been cited by other articles:


Home page
 ScienceHome page
D. A. Colon-Ramos, M. A. Margeta, and K. Shen
Glia Promote Local Synaptogenesis Through UNC-6 (Netrin) Signaling in C. elegans
Science, October 5, 2007; 318(5847): 103 - 106.
[Abstract] [Full Text] [PDF]

Home page
 J. Gen. Physiol.Home page
M. V. Espelt, A. Y. Estevez, X. Yin, and K. Strange
Oscillatory Ca2+ Signaling in the Isolated Caenorhabditis elegans Intestine: Role of the Inositol-1,4,5-trisphosphate Receptor and Phospholipases C {beta} and {gamma}
J. Gen. Physiol., September 26, 2005; 126(4): 379 - 392.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
H. Moribe, J. Yochem, H. Yamada, Y. Tabuse, T. Fujimoto, and E. Mekada
Tetraspanin protein (TSP-15) is required for epidermal integrity in Caenorhabditis elegans
J. Cell Sci., October 15, 2004; 117(22): 5209 - 5220.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 2003