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First published online September 9, 2005
doi: 10.1242/10.1242/dev.02023

Development 132, 4205-4210 (2005)
Published by The Company of Biologists 2005
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Meeting Review

TGFß signaling at the summit

Malcolm Whitman1,* and Laurel Raftery2

1 Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA 02115, USA
2 Cutaneous Biology Research Center, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129, USA

* Author for correspondence (e-mail: mwhitman{at}hms.harvard.edu)

SUMMARY

Ligands belonging to the transforming growth factor (TGF) ß superfamily have emerged as major regulators of a wide variety of developmental events, ranging from the earliest steps in germ layer patterning of the pre-gastrula embryo to tissue healing, regeneration and homeostasis in the adult. Recently, Caroline Hill and Bob Lechleider organized the third in a bi-annual series of FASEB meetings on TGFß signaling and development at Snowmass (CO, USA). This meeting highlighted the ongoing interplay between advances in our understanding of the molecular biology of TGFß family signaling and in investigations into its roles in specific developmental events.


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© The Company of Biologists Ltd 2005