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First published online August 14, 2006
doi: 10.1242/10.1242/dev.02515

Development 133, 3277-3282 (2006)
Published by The Company of Biologists 2006
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Meeting Review

A garden of Notch-ly delights

Gerry Weinmaster1,* and Raphael Kopan2

1 Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1737, USA.
2 Department of Molecular Biology and Pharmacology, Washington University, St Louis, MO 63301, USA.

* Author for correspondence (e-mail: gweinmaster{at}mednet.ucla.edu)

SUMMARY

Over the past decade, the Notch signaling pathway has been shown to be crucially important for normal metazoan development and to be associated with several human inherited and late onset diseases. The realization that altered Notch signaling contributes at various levels to human disease lead in May to the first meeting dedicated solely to Notch signaling in vertebrate development and disease in Madrid, Spain. Hosted by the Cantoblanco Workshops on Biology and organized by Tom Gridley, José Luis de la Pompa and Juan Carlos Izpisúa Belmonte, the meeting covered diverse aspects of this important signaling pathway.




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