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First published online 6 June 2007
doi: 10.1242/dev.003707

Development 134, 2541-2547 (2007)
Published by The Company of Biologists 2007
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Meeting Review

What lies at the interface of regenerative medicine and developmental biology?

Donald E. Ingber1,* and Michael Levin2

1 Vascular Biology Program, Departments of Pathology and Surgery, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
2 Center for Regenerative and Developmental Biology, Forsyth Institute, and Developmental Biology Department, Harvard School of Dental Medicine, Boston, MA 02115, USA.

* Author for correspondence (e-mail: donald.ingber{at}childrens.harvard.edu)

SUMMARY

At a recent Keystone Symposium on `Developmental Biology and Tissue Engineering', new findings in areas ranging from stem cell differentiation, embryonic pattern formation and organ regeneration to engineered cell microenvironments, synthetic biomaterials and artificial tissue fabrication were described. Although these new advances were exciting, this symposium clarified that biologists and engineers often view the challenge of tissue formation from different, and sometimes conflicting, perspectives. These dichotomies raise questions regarding the definition of regenerative medicine, but offer the promise of exciting new interdisciplinary approaches to tissue and organ regeneration, if effective alliances can be established.




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