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First published online September 28, 2007
doi: 10.1242/10.1242/dev.005926

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TGFß superfamily signaling: notes from the desert

¹ Waksman Institute, Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854-8020, USA.
² The Cancer Institute of New Jersey, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.
³ Departments of Internal Medicine and Molecular Genetics, Microbiology and Immunology, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA.

^* Author for correspondence (e-mail: padgett{at}waksman.rutgers.edu)

SUMMARY

The TGFß pathways play crucial roles in many developmental events, as well as contributing to many disease states. To provide a venue for both signaling and developmental research on TGFß, a FASEB-sponsored bi-annual meeting was initiated six years ago, the fourth of which was organized by Caroline Hill and Michael O'Connor and took place this July in Tucson, Arizona. The meeting highlighted major advances in our understanding of the structural and biochemical aspects of TGFß superfamily signaling, its intersection with other pathways, and its contribution to disease.