spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online October 24, 2008
doi: 10.1242/10.1242/dev.015701

Development 135, 3625-3641 (2008)
Published by The Company of Biologists 2008
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hammerschmidt, M.
Right arrow Articles by Wedlich, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hammerschmidt, M.
Right arrow Articles by Wedlich, D.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Review

Regulated adhesion as a driving force of gastrulation movements

Matthias Hammerschmidt1,2 and Doris Wedlich3

1 Max-Planck Institute of Immunobiology, D-79108 Freiburg, Germany.
2 Institute for Developmental Biology, Cologne University, D-50923 Cologne, Germany.
3 Zoological Institute II, University Karlsruhe (TH), D-76131 Karlsruhe, Germany.

e-mails: mhammers{at}uni-koeln.de; doris.wedlich{at}zi2.uni-karlsruhe.de

SUMMARY

Recent data have reinforced the fundamental role of regulated cell adhesion as a force that drives morphogenesis during gastrulation. As we discuss, cell adhesion is required for all modes of gastrulation movements in all organisms. It can even be instructive in nature, but it must be tightly and dynamically regulated. The picture that emerges from the recent findings that we review here is that different modes of gastrulation movements use the same principles of adhesion regulation, while adhesion molecules themselves coordinate the intra- and extracellular changes required for directed cell locomotion.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 DevelopmentHome page
D. C. Weiser, R. H. Row, and D. Kimelman
Rho-regulated Myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation
Development, July 15, 2009; 136(14): 2375 - 2384.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
M. Hammerschmidt and D. Wedlich
Regulated adhesion as a driving force of gastrulation movements
J. Cell Sci., November 15, 2008; 121(22): e1 - e1.
[Full Text]


© The Company of Biologists Ltd 2008