spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online May 8, 2009
doi: 10.1242/10.1242/dev.030403

Development 136, 1771-1783 (2009)
Published by The Company of Biologists 2009
This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Koerner, M. V.
Right arrow Articles by Barlow, D. P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Koerner, M. V.
Right arrow Articles by Barlow, D. P.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Review

The function of non-coding RNAs in genomic imprinting

Martha V. Koerner*, Florian M. Pauler*, Ru Huang and Denise P. Barlow{dagger}

Research Center for Molecular Medicine of the Austrian Academy of Sciences, Dr Bohr-Gasse 9/4, Vienna Biocenter, A-1030 Vienna, Austria.

{dagger} Author for correspondence (e-mail: denise.barlow{at}univie.ac.at)

SUMMARY

Non-coding RNAs (ncRNAs) that regulate gene expression in cis or in trans are a shared feature of prokaryotic and eukaryotic genomes. In mammals, cis-acting functions are associated with macro ncRNAs, which can be several hundred thousand nucleotides long. Imprinted ncRNAs are well-studied macro ncRNAs that have cis-regulatory effects on multiple flanking genes. Recent advances indicate that they employ different downstream mechanisms to regulate gene expression in embryonic and placental tissues. A better understanding of these downstream mechanisms will help to improve our general understanding of the function of ncRNAs throughout the genome.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
F. Winston
A transcription switch toggled by noncoding RNAs
PNAS, October 27, 2009; 106(43): 18049 - 18050.
[Full Text] [PDF]

Home page
 Genes Dev.Home page
M. S. Bartolomei
Genomic imprinting: employing and avoiding epigenetic processes
Genes & Dev., September 15, 2009; 23(18): 2124 - 2133.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
M. V. Koerner, F. M. Pauler, R. Huang, and D. P. Barlow
The function of non-coding RNAs in genomic imprinting
J. Cell Sci., June 1, 2009; 122(11): e1 - e1.
[Full Text]


© The Company of Biologists Ltd 2009