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Anatomy School, Cambridge
1 Author's address: University Anatomy School, Cambridge, U.K.
Received for publication 5 November 1954.
SUMMARY
The main impetus to the study of the nucleic acids and their functional significance within the cell has been mainly derived from the work of Caspersson and his school at Stockholm (Caspersson, 1950). From this source have come the generalizations that relatively high concentrations of ribonucleic acid (RNA) within the cytoplasm are characteristic of rapidly growing tissues, and thus of sites where proteins are being produced. Caspersson has provided evidence that the nucleus is intimately concerned in these synthetic processes. Brachet (1942) came independently to similar conclusions.
These are of importance in a number of related fields in biology, among which is the study of embryonic development. Davidson & Waymouth (1944) compared the nucleoprotein phosphorus of corresponding tissues of the sheep foetus at 9 and 10 weeks with those of the adult animal.
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