spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search    

The fully linked HTML version of this article has now been published.
Development ePress online publication date 10 Oct 2007
doi: 10.1242/dev.001131

This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
dev.001131v1
134/22/3959    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zilberman, D.
Right arrow Articles by Henikoff, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zilberman, D.
Right arrow Articles by Henikoff, S.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Review

Genome-wide analysis of DNA methylation patterns


Daniel Zilberman and Steven Henikoff*
* Author for correspondence (e-mail: steveh{at}fhcrc.org)

Cytosine methylation is the most common covalent modification of DNA in eukaryotes. DNA methylation has an important role in many aspects of biology, including development and disease. Methylation can be detected using bisulfite conversion, methylation-sensitive restriction enzymes, methyl-binding proteins and anti-methylcytosine antibodies. Combining these techniques with DNA microarrays and high-throughput sequencing has made the mapping of DNA methylation feasible on a genome-wide scale. Here we discuss recent developments and future directions for identifying and mapping methylation, in an effort to help colleagues to identify the approaches that best serve their research interests.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 BloodHome page
J. J. Alumkal
Through the looking glass
Blood, October 15, 2009; 114(16): 3363 - 3364.
[Full Text] [PDF]

Home page
 Clin. Cancer Res.Home page
M. T. McCabe, J. C. Brandes, and P. M. Vertino
Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications
Clin. Cancer Res., June 15, 2009; 15(12): 3927 - 3937.
[Abstract] [Full Text] [PDF]

Home page
 Plant CellHome page
S. Locatelli, P. Piatti, M. Motto, and V. Rossi
Chromatin and DNA Modifications in the Opaque2-Mediated Regulation of Gene Transcription during Maize Endosperm Development
PLANT CELL, May 1, 2009; 21(5): 1410 - 1427.
[Abstract] [Full Text] [PDF]

Home page
 Toxicol SciHome page
S. W. Edwards and R. J. Preston
Systems Biology and Mode of Action Based Risk Assessment
Toxicol. Sci., December 1, 2008; 106(2): 312 - 318.
[Abstract] [Full Text] [PDF]

Home page
 ScienceHome page
X. Zhang
The Epigenetic Landscape of Plants
Science, April 25, 2008; 320(5875): 489 - 492.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 2007