The fully linked HTML version of this article has now been published.
Development ePress online publication date 25 Feb 2004
doi: 10.1242/dev.01028
Research article
Synergistic interaction of three ERECTA-family receptor-like kinases controls Arabidopsis organ growth and flower development by promoting cell proliferation
Elena D. Shpak,
Chris T. Berthiaume,
Emi J. Hill,
and
Keiko U. Torii*
* Author for correspondence (e-mail: ktorii{at}u.washington.edu)
Growth of plant organs relies on coordinated cell proliferation followed by cell growth, but the nature of the cell-cell signal that specifies organ size remains elusive. The Arabidopsis receptor-like kinase (RLK) ERECTA regulates inflorescence architecture. Our previous study using a dominant-negative fragment of ERECTA revealed the presence of redundancy in the ERECTA-mediated signal transduction pathway. Here, we report that Arabidopsis ERL1 and ERL2, two functional paralogs of ERECTA, play redundant but unique roles in a part of the ERECTA signaling pathway, and that synergistic interaction of three ERECTA-family RLKs define aerial organ size. Although erl1 and erl2 mutations conferred no detectable phenotype, they enhanced erecta defects in a unique manner. Overlapping but distinct roles of ERL1 and ERL2 can be ascribed largely to their intricate expression patterns rather than their functions as receptor kinases. Loss of the entire ERECTA family genes led to striking dwarfism, reduced lateral organ size and abnormal flower development, including defects in petal polar expansion, carpel elongation, and anther and ovule differentiation. These defects are due to severely reduced cell proliferation. Our findings place ERECTA-family RLKs as redundant receptors that link cell proliferation to organ growth and patterning.
This article has been cited by other articles:
|
|
|
|
 
S. Tisne, M. Reymond, D. Vile, J. Fabre, M. Dauzat, M. Koornneef, and C. Granier
Combined Genetic and Modeling Approaches Reveal That Epidermal Cell Area and Number in Leaves Are Controlled by Leaf and Plant Developmental Processes in Arabidopsis
Plant Physiology,
October 1, 2008;
148(2):
1117 - 1127.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Gomez-Mena and R. Sablowski
ARABIDOPSIS THALIANA HOMEOBOX GENE1 Establishes the Basal Boundaries of Shoot Organs and Controls Stem Growth
PLANT CELL,
August 1, 2008;
20(8):
2059 - 2072.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. L.H. Hord, Y.-J. Sun, L. J. Pillitteri, K. U. Torii, H. Wang, S. Zhang, and H. Ma
Regulation of Arabidopsis Early Anther Development by the Mitogen-Activated Protein Kinases, MPK3 and MPK6, and the ERECTA and Related Receptor-Like Kinases
Mol Plant,
July 1, 2008;
1(4):
645 - 658.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
Y. Trusov, W. Zhang, S. M. Assmann, and J. R. Botella
G{gamma}1 + G{gamma}2 != G{beta}: Heterotrimeric G Protein G{gamma}-Deficient Mutants Do Not Recapitulate All Phenotypes of G{beta}-Deficient Mutants
Plant Physiology,
June 1, 2008;
147(2):
636 - 649.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Wang, Y. Liu, K. Bruffett, J. Lee, G. Hause, J. C. Walker, and S. Zhang
Haplo-Insufficiency of MPK3 in MPK6 Mutant Background Uncovers a Novel Function of These Two MAPKs in Arabidopsis Ovule Development
PLANT CELL,
March 1, 2008;
20(3):
602 - 613.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. George, S. M. Romanowsky, J. F. Harper, and R. A. Sharrock
The ACA10 Ca2+-ATPase Regulates Adult Vegetative Development and Inflorescence Architecture in Arabidopsis
Plant Physiology,
February 1, 2008;
146(2):
716 - 728.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. J. Pillitteri, S. M. Bemis, E. D. Shpak, and K. U. Torii
Haploinsufficiency after successive loss of signaling reveals a role for ERECTA-family genes in Arabidopsis ovule development
Development,
September 1, 2007;
134(17):
3099 - 3109.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. Hara, R. Kajita, K. U. Torii, D. C. Bergmann, and T. Kakimoto
The secretory peptide gene EPF1 enforces the stomatal one-cell-spacing rule
Genes & Dev.,
July 15, 2007;
21(14):
1720 - 1725.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
I. Roxrud, S. E. Lid, J. C. Fletcher, E. D. L. Schmidt, and H.-G. Opsahl-Sorteberg
GASA4, One of the 14-Member Arabidopsis GASA Family of Small Polypeptides, Regulates Flowering and Seed Development
Plant Cell Physiol.,
March 1, 2007;
48(3):
471 - 483.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Dardick, J. Chen, T. Richter, S. Ouyang, and P. Ronald
The Rice Kinase Database. A Phylogenomic Database for the Rice Kinome
Plant Physiology,
February 1, 2007;
143(2):
579 - 586.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
H. Wang, N. Ngwenyama, Y. Liu, J. C. Walker, and S. Zhang
Stomatal Development and Patterning Are Regulated by Environmentally Responsive Mitogen-Activated Protein Kinases in Arabidopsis
PLANT CELL,
January 1, 2007;
19(1):
63 - 73.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S.-K. Song, M. M. Lee, and S. E. Clark
POL and PLL1 phosphatases are CLAVATA1 signaling intermediates required for Arabidopsis shoot and floral stem cells
Development,
December 1, 2006;
133(23):
4691 - 4698.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. W. R. White
PEAPOD regulates lamina size and curvature in Arabidopsis
PNAS,
August 29, 2006;
103(35):
13238 - 13243.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. A. Birchler, H. Yao, and S. Chudalayandi
Unraveling the genetic basis of hybrid vigor
PNAS,
August 29, 2006;
103(35):
12957 - 12958.
[Full Text]
[PDF]
|
|
|
|
|
|
|
T. J. Strabala, P. J. O'Donnell, A.-M. Smit, C. Ampomah-Dwamena, E. J. Martin, N. Netzler, N. J. Nieuwenhuizen, B. D. Quinn, H. C.C. Foote, and K. R. Hudson
Gain-of-Function Phenotypes of Many CLAVATA3/ESR Genes, Including Four New Family Members, Correlate with Tandem Variations in the Conserved CLAVATA3/ESR Domain
Plant Physiology,
April 1, 2006;
140(4):
1331 - 1344.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. Colcombet, A. Boisson-Dernier, R. Ros-Palau, C. E. Vera, and J. I. Schroeder
Arabidopsis SOMATIC EMBRYOGENESIS RECEPTOR KINASES1 and 2 Are Essential for Tapetum Development and Microspore Maturation
PLANT CELL,
December 1, 2005;
17(12):
3350 - 3361.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Woodward, S. M. Bemis, E. J. Hill, S. Sawa, T. Koshiba, and K. U. Torii
Interaction of Auxin and ERECTA in Elaborating Arabidopsis Inflorescence Architecture Revealed by the Activation Tagging of a New Member of the YUCCA Family Putative Flavin Monooxygenases
Plant Physiology,
September 1, 2005;
139(1):
192 - 203.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
E. D. Shpak, J. M. McAbee, L. J. Pillitteri, and K. U. Torii
Stomatal Patterning and Differentiation by Synergistic Interactions of Receptor Kinases
Science,
July 8, 2005;
309(5732):
290 - 293.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Chevalier, M. Batoux, L. Fulton, K. Pfister, R. K. Yadav, M. Schellenberg, and K. Schneitz
STRUBBELIG defines a receptor kinase-mediated signaling pathway regulating organ development in Arabidopsis
PNAS,
June 21, 2005;
102(25):
9074 - 9079.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Nakhamchik, Z. Zhao, N. J. Provart, S.-H. Shiu, S. K. Keatley, R. K. Cameron, and D. R. Goring
A Comprehensive Expression Analysis of the Arabidopsis Proline-rich Extensin-like Receptor Kinase Gene Family using Bioinformatic and Experimental Approaches
Plant Cell Physiol.,
December 15, 2004;
45(12):
1875 - 1881.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Cano-Delgado, Y. Yin, C. Yu, D. Vafeados, S. Mora-Garcia, J.-C. Cheng, K. H. Nam, J. Li, and J. Chory
BRL1 and BRL3 are novel brassinosteroid receptors that function in vascular differentiation in Arabidopsis
Development,
November 1, 2004;
131(21):
5341 - 5351.
[Abstract]
[Full Text]
[PDF]
|
|
|
© The Company of Biologists Ltd 2004
