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First published online September 15, 2003
doi: 10.1242/10.1242/dev.00771


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From disease to development to cell biology and back

Marcos González-Gaitán

Max-Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany



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Fig. 1. Localisation of DNA label-retaining cells in three whole-mount preparations of a mouse tail epidermis. In this procedure, 10-day old mice receive four injections of BrdU over 48 hours to label mitotic cells. After a 70-day chase period, a whole-mount preparation of tail epidermis is immunolabelled for keratin 14 (red) and BrdU (green; to detect label-retaining cells, LRCs). HF, hair follicle; IFE, interfollicular epidermis; SG, sebaceous gland.

 

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© The Company of Biologists Ltd 2003