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First published online 11 April 2007
doi: 10.1242/dev.004416


Development 134, 1819-1822 (2007)
Published by The Company of Biologists 2007


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Wiring the nervous system: from form to function

Fumio Matsuzaki1 and Karuna Sampath2

1 RIKEN Centre for Developmental Biology, Kobe 650-0047, Japan.
2 Temasek Life Sciences Laboratory, National University of Singapore, 117604 Singapore.


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Fig. 1. Olfactory neuron projection in Drosophila and mouse. (A)In Drosophila, the Notch on-off code (red, Notch off; green, Notch on) is involved in coupling antennal neuron axonal projections with their odorant receptor expression. (B) In the mouse, the odorant receptor code is transformed into gene expression patterns that regulate axonal fasciculation via neuronal activity (red and green indicate different adhesion molecules). The X and Y labels next to the cell bodies indicate odorant receptor types. The diamonds indicate homophilic adhesions.

 

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© The Company of Biologists Ltd 2007