spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online August 25, 2008
doi: 10.1242/10.1242/dev.019901

Development 135, 2995-2999 (2008)
Published by The Company of Biologists 2008
This Article
Right arrow Summary Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bronner-Fraser, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bronner-Fraser, M.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

On the trail of the `new head' in Les Treilles

Marianne Bronner-Fraser

Division of Biology 139-74, California Institute of Technology, Pasadena, CA 91125, USA.


Figure 1
View larger version (33K):
[in this window]
[in a new window]

  		Fig. 1. Elements of cranial organization at the core of the `New Head Hypothesis'. The New Head Hypothesis (NHH) of Carl Gans and Glenn Nothcutt (Gans and Northcutt, 1983Go), as schematized in mouse (A-D) and human (E) embryos. (A-D) Schematics of embryonic day 9.5 (E9.5) mouse embryos, highlighting specific major tissue components of the NHH. The NHH posits that vertebrates exhibit unique characteristics, such as (A) an expanded alar plate of the forebrain; (B) formation of neurogenic sensory placodes from the surface cephalic ectoderm; (C) a migratory mesenchymal population of cranial neural crest cells that invade the branchial arches (BA) and surround the expanded forebrain and rostral primary sensory placodes; and (D) an expanded skeletal system to support the new rostrally expanded forebrain, rostral sensory capsules and BAs. (E) The hypothesized shift from a passive suction feeding protovertebrate to a predatory vertebrate with jaws made from modified BA elements necessitated a high degree of craniogenic developmental and functional integration. Abbreviations: BA, branchial arches; di, diencephalon; hb, hindbrain; mb, midbrain; olf, olfactory; op, optic; ot, otic; tel, telencephalon. (A-D) Modified, with permission, from Depew and Olsson (Depew and Olsson, 2008Go).

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?



© The Company of Biologists Ltd 2008