Fig. 2. Increased OP migration in the optic nerve of homozygous
TN-C-deficient mice when compared with heterozygous littermates. OP
migration analysis was performed as shown for Fig. 1. Data were obtained from experiments
at both P0 and P2, with three heterozygous and four homozygous null
animals with a C57Bl6J/CBA background and from an experiment at P2
with three heterozygous and three homozygous null animals with a 129
background. At both P0 or P2, more PDGF
R mRNA-positive cells were
found in each segments of the optic nerves of homozygous
TN-C-deficient mice when compared with heterozygous littermates
(Student’s t test: *P<0.05,
**P<0.01, ***P<0.001).
