Fig. 3. Increased OP cell migration on TN-C-null astroglial ECM
substrate. Measurements of rat OP migration from the edge of an
agarose drop show that after 1 and 2 days, the distance moved by the
cells is greater on the TN-C-null astroglial substrate than on the
wild-type astroglial substrate (Student’s t test:
**P<0.01,
***P<0.001). Note that the addition to the
substrate of purified TN-C at 40 µg/ml before the assay does not
reduce OP cell migration on the TN-C-null substrate. Results shown
represent mean±s.e.m. from three to six independent experiments
(WT, wild type; -/-, null).
