Fig. 8. Effects of injection of dnHrFGFR mRNA on expression of HrCA1, assessed by whole-mount in situ hybridization. (A) Expression of HrCA1 in a control tailbud embryo. Strong signals are evident in mesenchyme cells (mch) and in several neuronal cells (nu) in the anterior and dorsal trunk, while weak signal is evident in notochord cells (N, dotted line) and muscle cells (mu). (B) Embryo injected with HrFGFR mRNA. (C-E) Three examples of embryos injected with dnHrFGFR mRNA. The expression of HrCA1 was downregulated or suppressed. Scale bar is 100 µm for all panels.
