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Fig. 5. The lin-48 promoter elements share similarity with Pax-binding sites. (A) Some representative binding sites for mammalian PAX5, and a consensus sequence (Czerny et al, 1993). (B,C) Sequence of the two elements in the lin-48 promoter, and the mutant elements used to test the function of each site in vivo. Sequences that correspond to the consensus are underlined. Nucleic acids changed in the mutant promoters are in italics.





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