Fig. 3. Detection of BrdU labeling in transverse sections of the mandibular arch of E10.5 wild-type (A,C) and Prx1-/-Prx2-/- mutant (G,I) embryos. (B,D,F,H) False color representations of A,C,G,I (respectively) to aid in interpretation (see Materials and Methods section). The strength of labeling is indicated by a color series ranging from yellow (weakest) to dark red (strongest), corresponding to ranges of arbitrary units as indicated. Boxed areas in the false color figures indicate areas in which the mutant shows reduced labeling compared with the wild type. White horizontal line in left lower corner of D indicates 48 pixels. (E,J) Nearby sections from wild-type (E) and Prx1-/-Prx2-/- (J) embryos showing expression of Shh in red. Dorsal is upwards.
