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Fig. 7. Abnormal patterning of forebrain and midbrain territory in Otx2{lambda}/Otx2{lambda} and Otx2{lambda}/- mutant embryos. (A-O) Whole-mount in situ hybridisation of 8.5 d.p.c. wild-type (A,D,G,J,M), Otx2{lambda}/Otx2{lambda} (B,E,H,K,N) and Otx2{lambda}/- (C,F,I,L,O) embryos with probes for Otx2 (A-C), Fgf8 (D-F), Gbx2 (G-I), Wnt1 (J-L) and BF1 (M-O).





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