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Fig. 8. Head abnormalities in Otx2{lambda}/Otx2{lambda} and Otx2{lambda}/- embryos at 10.5 d.p.c. (A-L) Sagittal sections of 10.5 d.p.c. wild-type (A,D,G,J), Otx2{lambda}/Otx2{lambda} (B,E,H,K) and Otx2{lambda}/- (C,F,I,L) embryos hybridised with probes for Otx2 (A-C), Fgf8 (D-F), Gbx2 (G-I) and BF1 (J-L). The arrows point to the corresponding position of the Otx2 posterior border of expression. Fb, forebrain; Hb, hindbrain; Mb, midbrain.





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