Fig. 4. Kidney phenotypes in Sall1-deficient mice. (A) Kidneys of
wild-type newborn. Urinary bladder is filled with urine. (B) Kidneys of
Sall1-deficient newborn. Note kidneys are completely absent and the
urinary bladder is not inflated with urine. Other organs, such as adrenal
glands and testis, are normal. (C) Kidneys of another Sall1-deficient
newborn with severe bilateral kidney hypoplasia. Urine is absent from the
bladder. (D,E) Histological examination of kidney in wild-type mice. (F,G)
Histological examination of hypoplastic kidney in Sall1-deficient
mice. a, adrenal gland; bl, urinary bladder; k, kidney; t, testis. Scale bars:
100 µm
