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Fig. 4. Wild-type function of A1113hd in the male reproductive tract. (A) Sperm were present in the lumens of wild-type and A1113hd/13hd D11+/+ seminiferous tubules (arrows), but not in A11-/- D11+/+ testis. (B) The A1113hd/13hd D11+/+ ductus deferens showed a wild-type morphology, while A11-/- D11+/+ mutants showed a coiled configuration resulting from an anteriorization towards epidydimis (arrows). E, epididymis; T, testis; V, vas deferens.





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