Fig. 5. msh restores dorsal identity in the absence of Apterous. (A) apGal4/apUGO35 wing. (B) apGal4/apUGO35 uas-msh wing. The arrow indicates wing margin bristles of dorsal identity shown at higher magnification on the right. (C) apGal4/apUGO35 EP-fng wing. The anterior wing margin (AWM) differentiated ventral-type bristles in both dorsal and ventral surfaces (middle, illustrated below). (D) apGal4/apUGO35 EP-fng/uas-msh wing. Bristles in the dorsal AWM had dorsal identity. AWM bristles were more densely packed than in wild type. Note also the reduced size of the dorsal compartment and the ectopic bristles in the wing blade. (E) apGal4/+; uas-msh wing. The reduced size of the dorsal compartment, the ectopic bristles in the wing blade and increased bristle density in the AWM were similar to those in D. This is presumably caused by strong overexpression of msh under apGal4 control. Weaker overexpression using c765-gal4 did not produce these defects (see Fig. 3). Ectopic bristles in the A compartment are mechanosensory bristles; those located in the P compartment are thin bristles. The DV identity of the posterior bristles could not be determined.
