Fig. 7. Proposed model of the roles of LIN-11 in AWA and ASG specification. The forkhead domain transcription factor UNC-130 may function in the AWA/ASG precursors to asymmetrically allocate the unidentified determinants X and Y to the AWA and ASG neurons respectively. LIN-11 is expressed early in AWA, where it may act with X to initiate ODR-7 expression. ODR-7 then autoregulates as LIN-11 expression decreases. LIN-11 is expressed throughout adulthood in ASG, where it may act with Y to establish an ASG fate.
