Fig. 1. Homeotic transformations in a Su(z)12 mutant pharate adult male. Homeotic transformations are evident in several body segments. Sex combs, a structure normally only present on the first leg, are present on the first tarsal segments of all meso- and metathoracic legs (arrowheads); the antennae are partially transformed into legs (asterisk) and wings are much smaller and partially transformed into haltere-like structures (arrows). These homeotic transformations are consistent with inappropriate activation of several ANTC and BXC genes in the imaginal disc primordia of these structures (see text). The genotype of the animal shown is Su(z)125/Su(z)123 but similar homeotic phenotypes are observed in Su(z)125/Su(z)124 pharate adults; these mutant combinations die as pharate adults and never eclose from the pupal case.
