Fig. 2. Histology and cell proliferation in the proximal tibial epiphyseal growth plate at postnatal day 10. (A-C) Hematoxylin and Eosin stained sections of wild-type mice (A), ColII-FGFR31^ach transgenic mice (B) and ColII-FGFR31^ach transgenic mice (C). (D-F) Immunohistochemical detection of BrdU-labeled growth plate chondrocytes of wild-type (D), ColII-FGFR31^ach transgenic mice (E) and ColII-FGFR3^ach transgenic mice (F). (G) Quantification of the percentage of BrdU-positive cells in the epiphyseal growth plate of the proximal tibia (n=4-5).

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