Fig. 6. Expression of pax2.2, pax5 and pax8 is absent from the MHB region of spgm793 mutant embryos. Expression of pax2.2 (A-D), pax5 (E-H) and pax8 (I-L) at the five-somite stage (A,B,E,F), the nine-somite stage (I,J) and at 26 hpf (C,D,G,H,K,L) is shown. pax8 expression is first detected in wild-type embryos at the nine-somite stage (Pfeffer et al., 1998). Embryonic genotypes are indicated at top. Embryos are shown in lateral view, anterior towards the left and dorsal upwards. hb, hindbrain; os, optic stalk; ov, otic vesicle; s, somite (stage). Arrows indicate position of MHB.
