Fig. 1. Proteins of the Nephrin subfamily from Drosophila (Hibris and Sticks-and-Stones (Sns)), and worm, human, mouse and rat aligned with Clustal V. For Hbs, single lines lie over regions between conserved cysteines of Ig domains, the broken line is above the FN type-III like domain, the double line is over the putative transmembrane region and asterisks are over potential asparagine-linked glycosylation sites. The black indicates amino acid identity with respect to Hbs, while the gray indicates identity with respect to human Nephrin.
