Fig. 4. CNS phenotypes in Ptp52F and double mutants. Dissected late stage 16 embryos stained with mAb 1D4. (A) wild-type. (B) Ptp52F^18.3. (C) Ptp52F^18.3/Df(2R)JP4. The bundles are wavy and disorganized in B,C, and the outer bundle is sometimes missing (bracket). (B,C,E) Abnormal fasciculation of the middle and outer bundles (arrowheads). (D) Dlar^5.5Ptp52F^18.3. Bundle morphology in this double mutant reverts to wild type (compare with A-C). (E) Ptp10D¹,Ptp52F^18.3. (F) Ptp52F^18.3, Ptp69D¹/Df(3L)8ex25. 1D4-positive bundles in these two double mutants are more disorganized than in B,C, and the middle bundle is strongly affected (asterisks). Arrow, complete connective break.

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