Fig. 7. Model for Beat Ia-mediated regulation of membrane-anchored Beat adhesion complexes. In this model, a subset of axons expresses a membrane-anchored Beat (white diamonds) that forms heterophilic adhesion complexes with an unknown Beat receptor in trans. Beat Ia (black diamonds) is secreted by a different subset of growth cones at defasciculation choice points and binds to the Beat receptor, displacing the adhesion complexes and locally reducing axonal adhesivity.

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