Fig. 7. Localization of Na⁺ channel clusters in the initial axonal segment of cortical neurons. Comparable brain sections from wild-type (A) and treated MBP-TK (B) 1-20d mice were immunolabeled with anti-Na⁺ channel (PAN) antibodies. Nuclei of cortical neurons are visualized with DAPI staining. In both wild-type and treated MBP-TK animals, we observed a high concentration of Na⁺ channels (A,B) in the initial axonal segment of the cortical pyramidal neurons (arrowheads). Scale bar: 30 µm.

Return to article