Fig. 3. Electron microscopy of: (A) storage lysosomes (arrows) in hepatocyte in the vicinity of a bile canaliculus of a 6-month-old LAP/Acp5 deficient mouse (H, hepatocyte; bc, bile canaliculus); and (B) Kupffer cell (K) with storage lysosomes (I, Ito cell). (C) Higher magnification of storage lysosomes in a LAP/Acp5-deficient Kupffer cell. (D) LAP/Acp5-deficient spleen macrophage filled with storage lysosomes. (E) Sinus endothelial cell of a LAP/Acp5-deficient spleen with storage vacuoles (F) LAP/Acp5-deficient kidney fibroblast filled with storage vacuoles. Scale bars: 1.4 µm in A; 3.5 µm in B; 0.8 µm in C; 2.4 µm in D; 3.0 µm in E; 4.5 µm in F.
