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Fig. 7. The AP patterning system regulates the anterior domain of lower nuclear densities through transcription. (A) Wild-type embryo with anterior lower nuclear density. (B) Embryo from bcd nos tsl female with uniform nuclear density. (C) Embryo from female carrying six copies of bicoid showing expanded domain of lower nuclear densities. Arrowheads in A,C indicate the approximate border of the anterior domain. (D) Control wild-type embryo injected with water exhibiting an anterior domain. (E,F) Wild-type embryos injected with {alpha}-amanitin demonstrating uniform nuclear densities. The images are a focal plane through nuclei (green, as marked by DNA stain), and stained against Eve (blue in A-C). Note the uniform Eve in embryo from bcd nos tsl female (B) and the posterior shift in the Eve stripes in embryo from female carrying six copies of bicoid (C).





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