Fig. 3. Gli1 is expressed in the Gli2 domains from the knock-in allele. (A,C,E,G) Whole embryos and (B,D,F,H) high-power images of the limbs of the same embryos. (A,B) Wild-type E10.5 embryo stained with a Gli1 probe. (C,D) Wild-type embryo stained with a Gli2 probe. (E,F) Gli2^1ki/+ embryo stained with a Gli1 probe. (G,H) Gli2^1ki/1ki embryo stained with a Gli1 probe. Gli1 is expressed in the Gli1 (white arrows in F,H) and Gli2 (between red arrowheads in F,H) expression domains. Note the elevated Gli1 expression in H compared with F.

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