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Fig. 3. (A) Predicted amino-acid sequence of Minc protein showing four C2H2 zinc finger motifs (boxes). The shaded, underlined box indicates the position of the amino acid change associated with the minc[A388] mutation. In addition a conservative change of F to I at amino acid 140 was also present in the mutant. (B) Northern blot prepared from samples of embryonic (E), larval (L) and adult (A) poly(A)+ RNA hybridised to DNA probe LD 47926. A single transcript 3 kb long is revealed uniquely in RNA from embryos.





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