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Fig. 5. Western blots of lens cortical homogenates (C) and lens nuclear homogenates (N) from wild-type, {alpha}3 homozygous knockout (–/–), and {alpha}8 homozygous knockout (–/–) mice. The left panel shows the results obtained using an anti-{alpha}8 connexin antibody. The upper arrow indicates the intact {alpha}8 connexin protein band, while the lower arrow points to the cleaved bands of {alpha}8 connexin. The right panel shows the results obtained using an anti-{alpha}3 connexin antibody. The arrow indicates the cleaved forms of {alpha}3 connexin. The molecular markers (in kDa) are listed on the right-hand side.





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