Fig. 4. Defects in pharynx morphogenesis in cdl-1 mutant embryos. (A) Movement of the pharynx primordium toward the anterior of the head. Each picture was taken from a 4D recording of the same embryo. (a-d) Wild type and (e-h) cdl-1(e2501). Arrowheads indicate the anterior tips of the pharyngeal basement membrane. The buccal capsule is indicated in d and h (arrows). Time from first cleavage: (a) 390 minutes, (b) 435 minutes, (c) 480 minutes, (d) 610 minutes, (e) 390 minutes, (f) 480 minutes, (g) 600 minutes, and (h) 1140 minutes. (B, C) Merged images of immunostaining with a pharynx-specific antibody, 3NB12 (red), and Nomarski microscopy. A wild-type N2 L1 larva (B) and a cdl-1(e2501) embryo (C) that has elongated over 3-fold are shown. The buccal capsule (arrow) and the anterior tip of the pharynx (arrowhead) are indicated.
